Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?

Ayşegül Uğural, (Hacettepe Üniversitesi, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü, ANKARA, Türkiye)
Aylin Ayaz (Hacettepe Üniversitesi, Sağlık Bilimleri Fakültesi, Beslenme ve Diyetetik Bölümü, ANKARA, Türkiye)
Sakarya Tıp Dergisi
12 2
Yıl: 2020 Cilt: 10 Sayı: 1 Sayfa Aralığı: 162 - 170 Metin Dili: Türkçe DOI: 10.31832/smj.583473 İndeks Tarihi: 23-05-2021

Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?

Öz:
K vitamini yağda çözünen bir vitamin olup doğada filokinon (K1) ve menakinon (K2) formlarında bulunmaktadır. Menadion (K3) formu ise sentetik analog olarakkullanılmaktadır. K vitamini, metabolizmada K vitaminine bağımlı proteinlerin karboksilasyonundan sorumludur. Genellikle koagülasyon üzerine rolü olduğu bilinen Kvitamininin günümüzde kardiyovasküler hastalıklar, osteoporoz, vasküler kalsifikasyon, kanser, diyabet ve glisemik kontrol ile de ilişkisi olduğu gösterilmiştir. Son yıllardaise beyinde miyelinizasyonun yoğun olduğu bölgelerde Menakinon-4 (MK-4) formunda bulunduğu saptanmış ve eksikliğinin bilişsel performans ile bazı nörodejeneratifhastalıkların patogenezinde rol alabileceği belirtilmiştir. Bu etkisini Gas-6 ve protein S gibi moleküller aracılığıyla veya nöronları oksidatif stres hasarına karşı koruyarakgösterdiği düşünülmektedir. Atriyal fibrilasyon (AF) hastalarının sıklıkla kullandığı antikoagülanların ve K vitamini antagonisti olmayan antikoagülanların bilişselperformans ve demans üzerine etkisi ise tartışmalıdır. Bu derlemede K vitamini ve antikoagülanların bilişsel performans üzerine etkileri ele alınmıştır.
Anahtar Kelime:

Does Vitamin K Intake with Diet Affect Cognitive Performance?

Öz:
Vitamin K is a fat-soluble vitamin and is found in nature in the form of phylokinone (K1) and menakinone (K2). Menadione (K3) form is used as an synthetic analogue. Vitamin K is responsible for the carboxylation of vitamin K-dependent proteins in metabolism. Vitamin K, which is generally known to play a role in blood coagulation, has been shown to be associated with cardiovascular diseases, osteoporosis, vascular calcification, cancer, diabetes and glycemic control. In recent years, it has been found that menakinon-4 (MK-4) form is present in the regions where the myelinization is intense in the brain and its deficiency may be involved in the pathogenesis of cognitive performance and some neurodegenerative diseases. This effect is thought to be mediated by proteins such as Gas-6 and protein S or by protecting neurons from oxidative stress damage. The effect of anticoagulants frequently used by atrial fibrillation (AF) patients and non-vitamin K antagonist anticoagulants on cognitive performance and dementia is controversial. In this review article, the effects of vitamin K and anticoagulants on cognitive performance are discussed.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
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APA ugural a, Ayaz A (2020). Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?. , 162 - 170. 10.31832/smj.583473
Chicago ugural aysegul,Ayaz Aylin Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?. (2020): 162 - 170. 10.31832/smj.583473
MLA ugural aysegul,Ayaz Aylin Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?. , 2020, ss.162 - 170. 10.31832/smj.583473
AMA ugural a,Ayaz A Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?. . 2020; 162 - 170. 10.31832/smj.583473
Vancouver ugural a,Ayaz A Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?. . 2020; 162 - 170. 10.31832/smj.583473
IEEE ugural a,Ayaz A "Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?." , ss.162 - 170, 2020. 10.31832/smj.583473
ISNAD ugural, aysegul - Ayaz, Aylin. "Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?". (2020), 162-170. https://doi.org/10.31832/smj.583473
APA ugural a, Ayaz A (2020). Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?. Sakarya Tıp Dergisi, 10(1), 162 - 170. 10.31832/smj.583473
Chicago ugural aysegul,Ayaz Aylin Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?. Sakarya Tıp Dergisi 10, no.1 (2020): 162 - 170. 10.31832/smj.583473
MLA ugural aysegul,Ayaz Aylin Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?. Sakarya Tıp Dergisi, vol.10, no.1, 2020, ss.162 - 170. 10.31832/smj.583473
AMA ugural a,Ayaz A Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?. Sakarya Tıp Dergisi. 2020; 10(1): 162 - 170. 10.31832/smj.583473
Vancouver ugural a,Ayaz A Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?. Sakarya Tıp Dergisi. 2020; 10(1): 162 - 170. 10.31832/smj.583473
IEEE ugural a,Ayaz A "Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?." Sakarya Tıp Dergisi, 10, ss.162 - 170, 2020. 10.31832/smj.583473
ISNAD ugural, aysegul - Ayaz, Aylin. "Diyetle K vitamini Alımı Bilişsel Performansı Etkiler mi?". Sakarya Tıp Dergisi 10/1 (2020), 162-170. https://doi.org/10.31832/smj.583473
Sayfa Oluşturulma Tarihi
17-04-2024 19:38

İLETİŞİM

TÜBİTAK ULAKBİM TR Dizin

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Muhsin Yazıcıoğlu Caddesi No:51/C

06530 Çankaya / ANKARA +90 (312) 298 92 00

trdizin@tubitak.gov.tr

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