The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life
Yıl: 2020 Cilt: 30 Sayı: 3 Sayfa Aralığı: 184 - 190 Metin Dili: İngilizce DOI: 10.4274/tjcd.galenos.2020.2020-4-1 İndeks Tarihi: 31-05-2021
The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life
Öz: Aim: Post-haemorrhoidectomy pain adversely affects the patients’ comfort, length of hospitalisation and return to work/school and social life. Weinvestigated the effect of liposomal bupivacaine (LB) and aloe vera 2% cream (AVC) on post-haemorrhoidectomy pain and wound healing.Method: We established four treatment groups: G1, G2, G3 and G4. Then, we applied perianal submucosal 300 mg LB to 20 patients in G1intraoperatively; perianal 300 mg LB + local AVC to 20 patients in G2, 3 times a day, postoperatively; perianal AVC to 20 patients in G3 3 times a day,postoperatively and perianal placebo cream to 32 patients in G4 3 times a day, postoperatively. Patients’ pain at rest at the 12th, 24th and 36th hours andthe during defaecation at the 36th hour were scored using the visual analogue scale, “0” indicating “no pain” and “10” indicating “unbearable pain”.We recorded their needs for narcotic analgesics within postoperative 12 and 24 hours and for NSAID within 36 hours, as well as their return to sociallife and work and full recovery periods.Results: The difference was significant between the following groups: G1-G4 (p=0.042) & G2-G4 (p=0.002) in the need for narcotic analgesicswithin the first 24 hours, G2-G4 (p=0.002) in pain score at the 12th hour, G2-G4 (p<0.001) in pain score at the 24th hour, G2-G4 (p<0.001) & G3-G4(p=0.001) in pain score at the 36th hour, G2-G4 (p<0.001) in pain score during defaecation at the 36th hour and G2-G4 (p<0.001) in the return towork and social life.Conclusion: We recommend the combined use of LB and AVC after haemorrhoidectomy.
Anahtar Kelime: Hemoroidektomi Sonrası Lipozom Bupivacain ve Aleo Vera Krem Kullanımının Postoperatif Ağrıya, Analjezik İhtiyacına, Hospitalizasyon Süresine, İş ve Sosyal Yaşama Dönüşe Etkisi
Öz: Amaç: Hemoroidektomi sonrası ağrı, hastanın konforunu, hastanede kalış süresini, işe, okula ve sosyal hayata dönüşünü belirleyen en önemli etkendir. Lipozom bupivacain (LB) ve aleo vera %2 kremin (AVC) hemoroidektomi sonrası ağrı ve yara iyileşmesindeki etkinliğini araştırdık. Yöntem: G1, G2, G3 ve G4 adı altında dört farklı tedavi grubu oluşturuldu. Ligasure cihazı ile hemoroidektomi yapılan hastalardan G1’deki 20 hastaya intraoperatif perianal submukozal 300 mg LB, G2’deki 20 hastaya 300 mg LB (+) anal bölgeye postoperatif günde üç kez lokal AVC, G3’teki 20 hastaya postoperatif anal bölgeye günde üç kez AVC, G4’teki 32 hastaya postoperatif günde üç kez anal bölgeye plasebo krem uygulandı. Hastaların 12, 24 ve 36. saatteki istirahat ve de 36. saatteki defekasyon esnasındaki ağrıları visuel analog skalaya göre ağrısı yoksa “0”, dayanılmaz ağrısı var ise “10” puan olacak şekilde skorlandı. Postoperatif 12 ve 24 saat içerisindeki narkotik analjezik ihtiyaçları, 36 saat içerisindeki NSAİD ihtiyaçları, sosyal hayata ve işe geri dönüş süreleri ile tam iyileşme zamanları kaydedildi. Bulgular: İlk 24 saatteki narkotik analjezik ihtiyacı açısından G1-G4 (p=0,042), G2-G4 (p=0,002), 12. saatteki ağrı skoru açısından G2-G4 (p=0,002), 24. Saatteki ağrı skoru açısından G2-G4 (p<0,001), 36. saat istirahat ağrı skoru açısından G2-G4 (p<0,001) ve G3-G4 (p=0,001), 36. saat defekasyon esnası ağrı skoru açısından G2-G4 (p<0,001), iş ve sosyal hayata dönüş açısından G2-G4 (p<0,001) arasındaki farklar anlamlıydı. Sonuç: Hemoroidektomi sonrasında LB ve AVC’nin birlikte kullanılmasını öneriyoruz.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Kanlioz M, EKİCİ U (2020). The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life. , 184 - 190. 10.4274/tjcd.galenos.2020.2020-4-1 |
| Chicago | Kanlioz Murat,EKİCİ Uğur The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life. (2020): 184 - 190. 10.4274/tjcd.galenos.2020.2020-4-1 |
| MLA | Kanlioz Murat,EKİCİ Uğur The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life. , 2020, ss.184 - 190. 10.4274/tjcd.galenos.2020.2020-4-1 |
| AMA | Kanlioz M,EKİCİ U The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life. . 2020; 184 - 190. 10.4274/tjcd.galenos.2020.2020-4-1 |
| Vancouver | Kanlioz M,EKİCİ U The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life. . 2020; 184 - 190. 10.4274/tjcd.galenos.2020.2020-4-1 |
| IEEE | Kanlioz M,EKİCİ U "The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life." , ss.184 - 190, 2020. 10.4274/tjcd.galenos.2020.2020-4-1 |
| ISNAD | Kanlioz, Murat - EKİCİ, Uğur. "The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life". (2020), 184-190. https://doi.org/10.4274/tjcd.galenos.2020.2020-4-1 |
| APA | Kanlioz M, EKİCİ U (2020). The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life. Türk Kolon ve Rektum Hastalıkları Dergisi, 30(3), 184 - 190. 10.4274/tjcd.galenos.2020.2020-4-1 |
| Chicago | Kanlioz Murat,EKİCİ Uğur The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life. Türk Kolon ve Rektum Hastalıkları Dergisi 30, no.3 (2020): 184 - 190. 10.4274/tjcd.galenos.2020.2020-4-1 |
| MLA | Kanlioz Murat,EKİCİ Uğur The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life. Türk Kolon ve Rektum Hastalıkları Dergisi, vol.30, no.3, 2020, ss.184 - 190. 10.4274/tjcd.galenos.2020.2020-4-1 |
| AMA | Kanlioz M,EKİCİ U The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life. Türk Kolon ve Rektum Hastalıkları Dergisi. 2020; 30(3): 184 - 190. 10.4274/tjcd.galenos.2020.2020-4-1 |
| Vancouver | Kanlioz M,EKİCİ U The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life. Türk Kolon ve Rektum Hastalıkları Dergisi. 2020; 30(3): 184 - 190. 10.4274/tjcd.galenos.2020.2020-4-1 |
| IEEE | Kanlioz M,EKİCİ U "The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life." Türk Kolon ve Rektum Hastalıkları Dergisi, 30, ss.184 - 190, 2020. 10.4274/tjcd.galenos.2020.2020-4-1 |
| ISNAD | Kanlioz, Murat - EKİCİ, Uğur. "The Effects of Using Liposomal Bupivacaine and Aloe Vera Cream after Haemorrhoidectomy on Postoperative Pain, Need for Analgesics, Hospitalisation Period and Return to Work and Social Life". Türk Kolon ve Rektum Hastalıkları Dergisi 30/3 (2020), 184-190. https://doi.org/10.4274/tjcd.galenos.2020.2020-4-1 |
