Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey

Hüseyin SERVİ, (İstanbul Yeni Yüzyıl Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, İstanbul, Türkiye)
Ali ŞEN, (Marmara Üniversitesi, Eczacılık Fakültesi, Farmakognozi Anabilim Dalı, İstanbul, Türkiye)
Esra YILDIRIM SERVİ, (İstanbul Sabahattin Zaim Üniversitesi, Helal Gıda ve Ar-Ge Merkezi, İstanbul, Türkiye)
Ahmet DOĞAN (Marmara Üniversitesi, Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, İstanbul, Türkiye)
Journal of research in pharmacy (online)
10 0
Yıl: 2021 Cilt: 25 Sayı: 2 Sayfa Aralığı: 142 - 152 Metin Dili: İngilizce DOI: 10.29228/jrp.5 İndeks Tarihi: 31-05-2021

Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey

Öz:
Thechemical composition ofessential oils of aerial parts of Daucuscarota(DEO) and Foeniculum vulgare(FEO) was specifiedby GC/MS. Antidiabetic, anti-inflammatory, antioxidant,and antibacterial activities of oils were tested by -glucosidase inhibitory, 5-lipoxygenase inhibitory, DPPH/ABTS radical scavenging,and broth microdilution methods, respectively. Thirty components were identified in DEO (87.7%). Carotol (27.7%), elemicin (18.1%), and limonene (16.0%) were determined as the main compounds in DEO.Seventeen constituents were identified in FEO (100.0%). Estragole (34.0%), limonene (27.1%), and -pinene (19.5%) were found as major components in FEO. Both oils displayed weak antibacterial activity against Gram-negative bacteria. However, the oils were not effective on Gram-positive bacteria. DEO with IC50values of 1359 and 1579 μg/mL and FEO with IC50values of 3106 and 1654 μg/mL showed weak antioxidant activities against DPPH and ABTS radicals, respectively. DEO and FEO exhibited good anti-lipoxygenase activities with IC50values of 87.24 and 58.35 μg/mL,respectively. DEO presented significantly -glucosidase inhibitory activity with an IC50value of 44.78 μg/mL while FEO displayed poor activity with an IC50value of 1967 μg/mL. This study is the first report on the5-lipoxygenase and -glucosidase inhibitory activities of aerial parts of DEOas well as on the -glucosidase inhibitory activity of aerial parts ofFEO. These results indicated that DEO, which has a good antidiabetic and anti-inflammatory activity, is rich in oxygenated sesquiterpene and monoterpene. Also, it showed that FEO, which has a significant anti-inflammatory activity, is rich in monoterpene and phenylpropanoid.
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APA SERVI H, Sen A, YILDIRIM SERVİ E, doğan a (2021). Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey. , 142 - 152. 10.29228/jrp.5
Chicago SERVI HÜSEYIN,Sen Ali,YILDIRIM SERVİ ESRA,doğan ahmet Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey. (2021): 142 - 152. 10.29228/jrp.5
MLA SERVI HÜSEYIN,Sen Ali,YILDIRIM SERVİ ESRA,doğan ahmet Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey. , 2021, ss.142 - 152. 10.29228/jrp.5
AMA SERVI H,Sen A,YILDIRIM SERVİ E,doğan a Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey. . 2021; 142 - 152. 10.29228/jrp.5
Vancouver SERVI H,Sen A,YILDIRIM SERVİ E,doğan a Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey. . 2021; 142 - 152. 10.29228/jrp.5
IEEE SERVI H,Sen A,YILDIRIM SERVİ E,doğan a "Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey." , ss.142 - 152, 2021. 10.29228/jrp.5
ISNAD SERVI, HÜSEYIN vd. "Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey". (2021), 142-152. https://doi.org/10.29228/jrp.5
APA SERVI H, Sen A, YILDIRIM SERVİ E, doğan a (2021). Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey. Journal of research in pharmacy (online), 25(2), 142 - 152. 10.29228/jrp.5
Chicago SERVI HÜSEYIN,Sen Ali,YILDIRIM SERVİ ESRA,doğan ahmet Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey. Journal of research in pharmacy (online) 25, no.2 (2021): 142 - 152. 10.29228/jrp.5
MLA SERVI HÜSEYIN,Sen Ali,YILDIRIM SERVİ ESRA,doğan ahmet Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey. Journal of research in pharmacy (online), vol.25, no.2, 2021, ss.142 - 152. 10.29228/jrp.5
AMA SERVI H,Sen A,YILDIRIM SERVİ E,doğan a Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey. Journal of research in pharmacy (online). 2021; 25(2): 142 - 152. 10.29228/jrp.5
Vancouver SERVI H,Sen A,YILDIRIM SERVİ E,doğan a Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey. Journal of research in pharmacy (online). 2021; 25(2): 142 - 152. 10.29228/jrp.5
IEEE SERVI H,Sen A,YILDIRIM SERVİ E,doğan a "Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey." Journal of research in pharmacy (online), 25, ss.142 - 152, 2021. 10.29228/jrp.5
ISNAD SERVI, HÜSEYIN vd. "Chemical composition and biological activities of essential oils of Foeniculum vulgare Mill. and Daucus carota L. growing wild in Turkey". Journal of research in pharmacy (online) 25/2 (2021), 142-152. https://doi.org/10.29228/jrp.5
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23-04-2024 17:58

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