In the study, it was aimed to determine the effect of process parameters on the tensile strength of PLA samples produced by using 3D printer with the Fused Deposition Modeling (FDM) method. For this purpose, 2 different fill rates (20% and 100%), 3 different printing speeds (100, 150 and 200 mm/s), 3 different nozzle temperatures (180 °C, 205 °C and 220 °C) and 3 different pattern types (Cubic, Grid, Triangle) are selected. In the study, a higher tensile stress was obtained at a rate of 100%, compared to 20%. When the samples with 20% filling ratio are compared among themselves, the highest tensile stress value obtained was measured as 43.12 MPa in the Grid pattern type made at a nozzle temperature of 220 °C and at printing speed of 100 mm/s. The best result at 100% filling rate was 59.21MPa in the sample produced at 2200C, printing speed of 100 mm/s. In the study, statistical at analysis was done for samples with 20% fill rate. As a result of the variance analysis (ANOVA) method, the confidence level was achieved as 94.4%.