Yıl: 2021 Cilt: 7 Sayı: 1 Sayfa Aralığı: 31 - 38 Metin Dili: Türkçe DOI: 10.3153/FH21004 İndeks Tarihi: 02-06-2021

In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae)

Öz:
Padina pavonica (Linnaeus) Thivy 1960 is a brown algae that is antioxidant, antimicrobial, andanticancer effects and is generally used in soup, salad, and other dishes. However, no studies havebeen reported on safe consumption in humans to date. For this purpose, this study was conductedto determine the cytotoxic and genotoxic effects of P. pavonica on lymphocytes cultured fromhuman blood. The water extract of P. pavonica was added into culture tubes at various concentrations (0.5-1000 μg/mL). Cytotoxic effects were determined by MTT assay. Antioxidant/oxidantstatus was evaluated by total antioxidant capacity (TAC) and total oxidative status (TOS) assays.Genotoxic effects were investigated by sister chromatid exchanges and micronucleus assays. Ourresults showed that P. pavonica had no genotoxic effects, even at higher concentrations. 1000μg/mL concentration of P. pavonica caused an increase (P<0.05) TOS levels while significantlyreducing cell viability. However, low concentrations (50 and 100 μg/mL) significantly increased(P<0.05) TAC levels. In conclusion, P. pavonica can be safely consumed with its non-genotoxicand antioxidant properties in a manner dose-dependent.
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APA GÜNER A (2021). In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). , 31 - 38. 10.3153/FH21004
Chicago GÜNER ADEM In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). (2021): 31 - 38. 10.3153/FH21004
MLA GÜNER ADEM In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). , 2021, ss.31 - 38. 10.3153/FH21004
AMA GÜNER A In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). . 2021; 31 - 38. 10.3153/FH21004
Vancouver GÜNER A In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). . 2021; 31 - 38. 10.3153/FH21004
IEEE GÜNER A "In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae)." , ss.31 - 38, 2021. 10.3153/FH21004
ISNAD GÜNER, ADEM. "In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae)". (2021), 31-38. https://doi.org/10.3153/FH21004
APA GÜNER A (2021). In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). Food and Health, 7(1), 31 - 38. 10.3153/FH21004
Chicago GÜNER ADEM In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). Food and Health 7, no.1 (2021): 31 - 38. 10.3153/FH21004
MLA GÜNER ADEM In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). Food and Health, vol.7, no.1, 2021, ss.31 - 38. 10.3153/FH21004
AMA GÜNER A In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). Food and Health. 2021; 7(1): 31 - 38. 10.3153/FH21004
Vancouver GÜNER A In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae). Food and Health. 2021; 7(1): 31 - 38. 10.3153/FH21004
IEEE GÜNER A "In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae)." Food and Health, 7, ss.31 - 38, 2021. 10.3153/FH21004
ISNAD GÜNER, ADEM. "In vitro risk assessment of Padina pavonica (Linnaeus) (Brown algae)". Food and Health 7/1 (2021), 31-38. https://doi.org/10.3153/FH21004