Mehmet KILIÇ
(Fırat Üniversitesi, Tıp Fakültesi, Pediatri Anabilim Dalı, Alerji ve İmmünoloji Anabilim Dalı, Elazığ, Türkiye)
Erdal TAŞKIN
(Fırat Üniversitesi, Tıp Fakültesi, Pediatri Anabilim Dalı, Neonatoloji Anabilim Dalı, Elazığ, Türkiye)
Mahir TAN
(Fırat Üniversitesi, Tıp Fakültesi, Pediatri Anabilim Dalı, Elazığ, Türkiye)
Alp GÖZÜTOK
(Fırat Üniversitesi, Tıp Fakültesi, Pediatri Anabilim Dalı, Elazığ, Türkiye)
Yıl: 2020Cilt: 18Sayı: 2ISSN: 1308-9234Sayfa Aralığı: 105 - 109İngilizce

37 0
Association of Cold Urticaria with Aquagenic Urticaria in an Adolescent Girl: A Case Report
Physical urticaria is a heterogeneous group of inducible conditions in which symptoms are induced by exogenous physical triggers suchas cold, water, heat, and mechanical stimuli, acting on the skin. Our case involves a sixteen-year-old female patient who presented witherythema, small wheals and pruritus on her skin after contact with water and cold. After conducting water and ice cube provocation testsin addition to her medical history and physical examination, the patient was diagnosed with aquagenic urticaria (AU) and cold urticaria(CU). Her complaints had started 20 days before presentation. Regardless of the temperature and the source of water, her symptomsincreased after contact with water, and the physical examination disclosed thoracic scoliosis. Symptoms were significantly relievedafter one month of antihistamine and liquid petrolatum treatment. However, the patient developed complaints of urticaria, itching andangioedema in the contact areas of the body after contact with cold air, cold water, and cold objects in the winter season. She was testedwith ice cubes and the result was positive. We started treatment with omalizumab, and her symptoms improved at the eighth week of thistreatment. Here we present an adolescent female patient diagnosed with CU and AU.
Dergititle.paper.fact_presentationErişime Açık
  • 1. Magerl M, Altrichter S, Borzova E, Giménez-Arnau A, Grattan CEH, Lawlor F, et al. The definition, diagnostic testing, and management of chronic inducible urticarias the EAACI/GA(2) LEN/EDF/UNEV consensus recommendations 2016 update and revision. Allergy 2016;71:780-802.
  • 2. Rothbaum R, McGee JS. Aquagenic urticaria: Diagnostic and management challenges. J Asthma Allergy 2016;9:209-13.
  • 3. Luong KV, Nguyen LT. Aquagenic urticaria: Report of a case and review of the literature. Ann Allergy Asthma Immunol 1998;80:483-5.
  • 4. Treudler R, Tebbe B, Steinhoff M, Orfanos CE. Familial aquagenic urticaria associated with familial lactose intolerance. J Am Acad Dermatol 2002;47:611-3.
  • 5. Seize MB, Ianhez M, de Souza PK, Rotta O, Cestari SCP: Familial aquagenic urticaria: report of two cases and literature review. An Bras Dermatol 2009;84:530-3.
  • 6. Arıkan-Ayyıldız Z, Işık S, Cağlayan-Sözmen S, Karaman O, Uzuner N. Cold, cholinergic and aquagenic urticaria in children: Presentation of three cases and review of the literature. Turk J Pediatr 2013;55:94-8.
  • 7. Yavuz ST, Sahiner UM, Tuncer A, Sackesen C. Aquagenic urticaria in 2 adolescents. J Investig Allergol Clin Immunol 2010;20:624-5.
  • 8. Kai AC, Flohr C. Aquagenic urticaria in twins. World Allergy Organ J 2013; 6:2.
  • 9. Ozkaya E, Elinç-Aslan MS, Yazici S. Aquagenic urticaria and syncope associated with occult papillary thyroid carcinoma and improvement after total thyroidectomy. Arch Dermatol 2011;147:1461-2.
  • 10. Dice JP. Physical urticaria. Immunol Allergy Clin North Am 2004;24:225-46.
  • 11. Seol JE, Kim DH, Park SH, Kang JN, Sung HS, Kim H. Aquagenic Urticaria Diagnosed by the Water Provocation Test and the Results of Histopathologic Examination. Ann Dermatol 2017;29:341-5.
  • 12. Frances AM, Fiorenza G, Frances RJ. Aquagenic urticarial: Report of a case. Allergy and Asthma Proc 2004;25:195-7.
  • 13. Park H, Kim HS, Yoo DS, Kim JW, Kim CW, Kim SS, et al. Aquagenic urticaria: A report of two cases. Ann Dermatol 2011;23:371-4.
  • 14. Czarnetzki BM, Breetholt KH, Traupe H. Evidence that water acts as a carrier for an epidermal antigen in aquagenic urticaria. J Am Acad Dermatol 1986;15:623-7.
  • 15. Kulthanan K, Tuchinda P, Chularojanamontri L, Kiratiwongwan R. Cold Urticaria: Clinical Features and Natural Course in a Tropical Country. Allergy Asthma Immunol Res 2019;11:538- 47.
  • 16. Deza G, Brasileiro A, Bertolín-Colilla M, Curto-Barredo L, Pujol RM, Giménez-Arnau AM. Acquired cold urticaria: Clinical features, particular phenotypes, and disease course in a tertiary care center cohort. J Am Acad Dermatol 2016;75:918-24.
  • 17. Mathelier-Fusade P, Aissaoui M, Chabane MH, Mounedji N, Leynadier F. Association of cold urticaria and aquagenic urticaria. Allergy 1997;52:678-9.
  • 18. Baptist AP, Baldwin JL. Aquagenic urticaria with extracutaneous manifestations. Allergy Asthma Proc 2005;26:217-20.
  • 19. Sibbald RG, Black AK, Eady RA, James M, Greaves MW. Aquagenic urticaria: Evidence of cholinergic and histaminergic basis. Br J Dermatol 1981;105:297-302.
  • 20. Tkach JR. Aquagenic urticaria. Cutis 1981;28:454-63.
  • 21. Gallo R, Campisi C, Agnoletti A, Parodi A. Aquagenic urticaria recurring after epilation and contact with sea water. Contact Dermatitis 2015;73:313-24.

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