The Milesian School has been the subject of various specific studies in the history of philosophy as the starting position for the history of western philosophy. These studies are not limited to the history of philosophy and they also constitute a specific subject area for the studies of various fields that focus on explaining humanity’s evolution of thought. In particular, those elements that are defined as the conditions for the emergence of philosophy are not only affected by the perspectives that interpret the history of thought, but also, by the approaches concerning the progress of civilizations and are becoming a criterion based upon the point of view. Although there is no single definition agreed upon on the philosophy, there is a single perception of philosophy that emerged, and the properties of the Milesian philosophers are placed at the center of this perception. Does the philosophy, which we see as the effort to look at life and the universe as a whole, carry the properties identified with the Milesians? Within this scope, one of the goals of this study has been to determine whether the ways of interpreting the significance of Milesian School bring along various approaches or attitudes. Another goal is to examine whether the definitions made on the subject of the Milesian School comply with the condition of philosophy and cultures today. In parallel with these goals, the sources on the history of philosophy from various traditions, as well as other related sources, have been examined, and the attempt has been made to evaluate the similarities and differences, in addition to their points of view and the evaluations made concerning the beginning of philosophy and the Milesian School.