Dilek HANÇERLİOĞULLARI
(Kırıkkale Üniversitesi, Diş Hekimliği Fakültesi, Endodonti A.D., Kırıkkale, Türkiye)
Ali ERDEMİR
(Kırıkkale Üniversitesi, Diş Hekimliği Fakültesi, Endodonti A.D., Kırıkkale, Türkiye)
Yıl: 2020Cilt: 22Sayı: 2ISSN: 2148-9645 / 2148-9645Sayfa Aralığı: 281 - 287Türkçe

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REJENERATİF ENDODONTİDE İSKELE BİYOMATERYALLERİ
Doku mühendisliğiyle; kanser, travma ya da hastalıklar nedeniyle kaybolan dokunun fizyolojik ve fonksiyonel restorasyonu hedeflenir. Rejenerasyon kavramı multidisipliner bir yaklaşımla; kök hücreler, iskele ve büyüme faktörlerini içermektedir. Tedavilerin daha başarılı olabilmesi için kök hücrelerinin organizasyonu ve vaskülarizasyonu sırasında doku oluşumunu destekleyen geçici ekstrasellüler matrikslere (iskeleler) ihtiyaç vardır. İskele tasarımı, doku mühendisliği için kritik öneme sahiptir. Doku mühendisliğiyle, diş hekimliği alanında da umut vaat edici sonuçlara ulaşılmıştır. Araştırma verileri; dişin tüm kronu yerine daha küçük boyutlarda diş dokusunun üretilebildiğini göstermiştir. Rejeneratif endodontik tedavilerde, doğal ve doğal olmayan (fabrikasyon) iskeleler kullanılır. Bu derlemenin amacı, rejeneratif tedavilerde kullanılan iskele çeşitlerinin tanımlanması ve güncel literatür çalışma sonuçlarının değerlendirilmesidir.
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