Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia
Yıl: 2021 Cilt: 7 Sayı: 1 Sayfa Aralığı: 89 - 95 Metin Dili: İngilizce DOI: 10.17954/amj.2021.2520 İndeks Tarihi: 07-06-2021
Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia
Öz: Objective: The aim of this study was to investigate the role of 25-hydroxyvitamin D (25OHD)concentrations on symptoms in the Fibromyalgia Syndrome (FMS).Material and Methods: 80 female patients diagnosed with FMS were divided into 2 groupsaccording to serum 25OHD concentration: 25OHD <20 ng/ml and 25OHD ≥20 ng/ml. Weevaluated all patients with the Visual Analogue Scale (VAS), Fibromyalgia Impact Questionnaire(FIQ), Short Form-36 (SF-36), Beck Depression Inventory (BDI), Pittsburgh Sleep Quality Index(PSQI), Epworth Sleepiness Scale (ESS), and Arizona Sexual Experience Scale (ASES).Results: The VAS, FIQ, PSQI, ESS, and physical role components of the SF-36 scores weresignificantly higher in patients with 25OHD <20 ng/ml than those with 25OHD ≥20 ng/ml (p value0.01; 0.037; 0.016; 0.031, respectively). No significant difference was found between the groups forthe BDI and ASES scores (p>0.05). Spearman correlation analysis showed a significant negativecorrelation between the serum 25OHD concentration and the VAS, FIQ, PSQI and ESS scores (pvalues 0.01, 0.02, 0.02, 0.03, respectively).Conclusion: Vitamin D deficiency may be a factor associated with symptom severity, sleep andwakefulness problems, and physical function in FMS. Therefore, serum 25OHD status should beevaluated in patients with FMS and its importance in treatment management should not be ignored.
Anahtar Kelime: Fibromiyaljili Hastalarda Vitamin Dʼnin Ağrı Şiddeti, Yaşam Kalitesi, Depresyon ve Uyku Üzerine Etkileri
Öz: Amaç: Bu çalışmanın amacı, serum 25 hidroksivitamin D konsantrasyonlarının Fibromiyalji Sendromuʼndaki (FMS) semptomlar üzerindeki rolünü araştırmaktır. Gereç ve Yöntemler: FMS tanısı almış 80 kadın hasta serum 25-hidroksivitamin D (25OHD) konsantrasyonuna göre 2 gruba ayrıldı: 25OHD <20 ng/ml ve 25OHD≥20 ng/ml. Tüm hastalar Görsel Analog Skala (VAS), Fibromiyalji Etki Anketi (FIQ), Kısa Form-36 (SF-36), Beck Depresyon Envanteri (BDI), Pittsburgh Uyku Kalitesi İndeksi (PSQI), Epworth Uykululuk Skalası (ESS) ve Arizona Cinsel Deneyim Ölçeği (ASES) ile değerlendirildi. Bulgular: VAS, FIQ, PSQI, ESS ve SF-36’nın fiziksel rol komponenti skorları 25OHD <20 ng/ ml olan hastalarda 25OHD ≥20 ng/ml olan hastalara göre anlamlı olarak daha yüksekti (p değeri, sırasıyla 0.01; 0.037; 0.016; 0.031). BDI ve ASES skorlarında gruplar arasında anlamlı farklılık saptanmadı (p>0.05). Spearman korelasyon analizinde serum 25OHD düzeyleri ve VAS, FIQ, PSQI and ESS skorları arasında anlamlı negatif korelasyon saptandı (p değeri, sırasıyla 0.01, 0.02, 0.02, 0.03). Sonuç: Vitamin D eksikliği FMS’de semptom şiddeti, uyku ve uyanıklık problemleri ve fiziksel fonksiyon ile ilişkili bir faktör olabilir. Bu nedenle FMS’li hastalarda serum 25OHD düzeyleri değerlendirilmeli ve bunun tedavi yönetimindeki önemi göz ardı edilmemelidir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Yalcin U, Badıl Güloğlu S (2021). Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia. , 89 - 95. 10.17954/amj.2021.2520 |
| Chicago | Yalcin Umit,Badıl Güloğlu Sevtap Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia. (2021): 89 - 95. 10.17954/amj.2021.2520 |
| MLA | Yalcin Umit,Badıl Güloğlu Sevtap Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia. , 2021, ss.89 - 95. 10.17954/amj.2021.2520 |
| AMA | Yalcin U,Badıl Güloğlu S Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia. . 2021; 89 - 95. 10.17954/amj.2021.2520 |
| Vancouver | Yalcin U,Badıl Güloğlu S Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia. . 2021; 89 - 95. 10.17954/amj.2021.2520 |
| IEEE | Yalcin U,Badıl Güloğlu S "Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia." , ss.89 - 95, 2021. 10.17954/amj.2021.2520 |
| ISNAD | Yalcin, Umit - Badıl Güloğlu, Sevtap. "Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia". (2021), 89-95. https://doi.org/10.17954/amj.2021.2520 |
| APA | Yalcin U, Badıl Güloğlu S (2021). Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia. Akdeniz Tıp Dergisi, 7(1), 89 - 95. 10.17954/amj.2021.2520 |
| Chicago | Yalcin Umit,Badıl Güloğlu Sevtap Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia. Akdeniz Tıp Dergisi 7, no.1 (2021): 89 - 95. 10.17954/amj.2021.2520 |
| MLA | Yalcin Umit,Badıl Güloğlu Sevtap Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia. Akdeniz Tıp Dergisi, vol.7, no.1, 2021, ss.89 - 95. 10.17954/amj.2021.2520 |
| AMA | Yalcin U,Badıl Güloğlu S Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia. Akdeniz Tıp Dergisi. 2021; 7(1): 89 - 95. 10.17954/amj.2021.2520 |
| Vancouver | Yalcin U,Badıl Güloğlu S Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia. Akdeniz Tıp Dergisi. 2021; 7(1): 89 - 95. 10.17954/amj.2021.2520 |
| IEEE | Yalcin U,Badıl Güloğlu S "Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia." Akdeniz Tıp Dergisi, 7, ss.89 - 95, 2021. 10.17954/amj.2021.2520 |
| ISNAD | Yalcin, Umit - Badıl Güloğlu, Sevtap. "Effects of Vitamin D on Pain Severity, Quality of Life, Depression and Sleep in Patients with Fibromyalgia". Akdeniz Tıp Dergisi 7/1 (2021), 89-95. https://doi.org/10.17954/amj.2021.2520 |
