Yıl: 2020 Cilt: 28 Sayı: 1 Sayfa Aralığı: 9 - 12 Metin Dili: İngilizce İndeks Tarihi: 10-05-2021

Bilateral Optic Neuropathy in a Patient with Imatinib Usage

Öz:
A 59-year-old woman presented with a painless vision loss in her left eye for five days. The nasal side of the right optic nerve head was mildly oedematous and hyperaemic, and the left optic nerve head was oedematous and hyperaemic. She was diagnosed as bilateral optic neuropathy. Imatinib was stopped, intravenous metilprednisolone was given for a week. The vision and fundus findings recovered in a few days. After 2 months imatinib was restarted, there was no ocular side effects until now. Imatinib is an important drug in the treatment ofchronic myeloid leukemia, but bilateral optic neuropathy, which is a serious ocular side effect, may be seen related to imatinib mesylate usage.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
  • 1. Druker BJ, sawyers CL, Kantarjian H, Resta DJ, Reese sF, Ford JM, et al. activity of a specific inhibitor of the BCR-aBL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with philadelphia chromosome. N engl J Med. 2001;344(14):1038-42. [Crossref] [pubMed]
  • 2. Ho WL, Wong H, Yau t. the ophthalmological complications of targeted agents in cancer therapy: what do we need to know as ophthalmologists? acta ophthalmologica. 2012;91(7):604-9. [Crossref] [pubMed]
  • 3. Fraunfelder FW, solomon J, Druker BJ, esmaeli B, Kuyl J. ocular side effects associated with imatinib mesylate (Gleevec). J ocul pharmacol ther. 2003;19(4):371-5. [Crossref] [pubMed]
  • 4. Kwon sI, Lee DH, Kim YJ. optic disc edema as a possible complication of imatinib mesylate (Gleevec). Jpn J ophthalmol. 2008;52(4): 331-3. [Crossref] [pubMed]
  • 5. Kusumi e, arakawa a, Kami M, Kato D, Yuji K, Murashige N, et al. Visual disturbance due to retinal edema as a complication of imatinib. Leukemia. 2004;18(6):1138-9. [Crossref] [pubMed]
  • 6. DeLuca C, shenouda-awad N, Haskes C, Wrzesinski s. Imatinib mesylate (Gleevec) induced unilateral optic disc edema. optom Vis sci. 2012;89(10):e16-22. [Crossref] [pubMed]
  • 7. Govind Babu K, attili Vs, Bapsy pp, anupama G. Imatinib induced optic neuritis in a patient of chronic myeloid leukemia. Int ophthalmol. 2007;27(1):43-4. [Crossref] [pubMed]
  • 8. Napolitano M, santoro M, Mancuso s, Carlisi M, Raso s, tarantino G, et al. Late onset of unilateral optic disc edema secondary to treatment with imatinib mesylate. Clin Case Rep. 2017;5(10)1573-5. [Crossref] [pubMed] [pMC]
APA Dönmez Gün R, KOÇKAR A, Altunrende B, sengul e (2020). Bilateral Optic Neuropathy in a Patient with Imatinib Usage. , 9 - 12.
Chicago Dönmez Gün Raziye,KOÇKAR ALEV,Altunrende Burcu,sengul elvan alper Bilateral Optic Neuropathy in a Patient with Imatinib Usage. (2020): 9 - 12.
MLA Dönmez Gün Raziye,KOÇKAR ALEV,Altunrende Burcu,sengul elvan alper Bilateral Optic Neuropathy in a Patient with Imatinib Usage. , 2020, ss.9 - 12.
AMA Dönmez Gün R,KOÇKAR A,Altunrende B,sengul e Bilateral Optic Neuropathy in a Patient with Imatinib Usage. . 2020; 9 - 12.
Vancouver Dönmez Gün R,KOÇKAR A,Altunrende B,sengul e Bilateral Optic Neuropathy in a Patient with Imatinib Usage. . 2020; 9 - 12.
IEEE Dönmez Gün R,KOÇKAR A,Altunrende B,sengul e "Bilateral Optic Neuropathy in a Patient with Imatinib Usage." , ss.9 - 12, 2020.
ISNAD Dönmez Gün, Raziye vd. "Bilateral Optic Neuropathy in a Patient with Imatinib Usage". (2020), 9-12.
APA Dönmez Gün R, KOÇKAR A, Altunrende B, sengul e (2020). Bilateral Optic Neuropathy in a Patient with Imatinib Usage. Türkiye Klinikleri Journal of Case Reports, 28(1), 9 - 12.
Chicago Dönmez Gün Raziye,KOÇKAR ALEV,Altunrende Burcu,sengul elvan alper Bilateral Optic Neuropathy in a Patient with Imatinib Usage. Türkiye Klinikleri Journal of Case Reports 28, no.1 (2020): 9 - 12.
MLA Dönmez Gün Raziye,KOÇKAR ALEV,Altunrende Burcu,sengul elvan alper Bilateral Optic Neuropathy in a Patient with Imatinib Usage. Türkiye Klinikleri Journal of Case Reports, vol.28, no.1, 2020, ss.9 - 12.
AMA Dönmez Gün R,KOÇKAR A,Altunrende B,sengul e Bilateral Optic Neuropathy in a Patient with Imatinib Usage. Türkiye Klinikleri Journal of Case Reports. 2020; 28(1): 9 - 12.
Vancouver Dönmez Gün R,KOÇKAR A,Altunrende B,sengul e Bilateral Optic Neuropathy in a Patient with Imatinib Usage. Türkiye Klinikleri Journal of Case Reports. 2020; 28(1): 9 - 12.
IEEE Dönmez Gün R,KOÇKAR A,Altunrende B,sengul e "Bilateral Optic Neuropathy in a Patient with Imatinib Usage." Türkiye Klinikleri Journal of Case Reports, 28, ss.9 - 12, 2020.
ISNAD Dönmez Gün, Raziye vd. "Bilateral Optic Neuropathy in a Patient with Imatinib Usage". Türkiye Klinikleri Journal of Case Reports 28/1 (2020), 9-12.