Chromhidrosisis a rare condition with a characteristic presentation of the secretion of colored sweat by apocrine or eccrine sweat glands. Eccrine chromhidrosis may occur by some water-soluble dyes in the systemic circulation, as a result of drug metabolism such as quinine, bisacodyl, clofazimine etc. or due to contamination of micro-organisms and rarely hyperbilirubinemia. The first and most important step for diagnosis of eccrine chromhidrosis is clinical evaluation. In the treatment of chromhidrosis, the suspected dye or drug should be eliminated from the body. This case report describes a patient who was diagnosed with eccrine chromhidrosis as a result of drug metabolism. The patient presented to the outpatient family medicine clinic of Ibn-i Sina Hospital with a complaint of blue sweating.