Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era
Yıl: 2020 Cilt: 44 Sayı: 2 Sayfa Aralığı: 86 - 92 Metin Dili: İngilizce DOI: 10.5152/cjm.2020.20009 İndeks Tarihi: 16-05-2021
Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era
Öz: Objective: Focal cortical dysplasia (FCD) is the most common cause of focal epilepsy in children and adults. The long-term seizure outcome has been reported in children, but very limited data are available for adults. The aim of this retrospective study is to provide long-term seizure outcome in adults with isolated FCD.Methods: A total of 23 adult patients operated on type I and II FCD were included. Medical history, seizure semiology, and radiological features were reviewed from the patients’ charts. Long-term seizure outcome was obtained with telephone interviews and last follow-up data available in archive.Results: At the last follow-up, 16 patients (69.6%) were totally seizure free even without aura and 7 patients (30.4%) continued to have seizure. Both type I (75%) and type II FCD (63.7%) showed higher seizure-free rate, and no significant difference was found (p=0.6).Conclusion: Surgery is safe and results in high seizure-free rate in adult patients with isolated FCD, but it is not enough because we cannot still explain why some patients continue to have seizure after complete removal of the dysplastic area.
Anahtar Kelime: Modern Çağda Yetişkin Fokal Kortikal Displazi Hastalarının Nöbet Sonlanımı
Öz: Amaç: Fokal kortikal displazi (FKD) yetişkin ve çocuklardaki en sık görülen fokal epilepsi sebebidir. Uzun dönem nöbet akıbetleri çocuklarda raporlanmıştır ancak erişkin hastalar için etkin veriler oldukça sınırlıdır. Bu retrospektif çalışmadaki amaç erişkin izole FKD hastalarında uzun dönem nöbet sonuçlarının ortaya koyulmasıdır. Yöntem: Toplamda 23 tip-1 ve tip-2 FKD hastası opere edilmiştir. Hastaların tıbbi öyküsü, nöbet semiyolojisi ve radyolojik özellikleri incelendi. Uzun dönem nöbet durumları hakkında bilgiler, hastalarla yapılan telefon görüşmeleri ve güncel arşiv bilgilerinden edinildi. Bulgular: On altı hasta aurasız olarak tamamen nöbetsiz izlenmiştir, 7 hastanın nöbetleri devam etmektedir. Hem tip-1 hem de tip-2 FKD’de nöbetsizlik oranı daha yüksektir ve her ikisi arasında sonuçlarda anlamı fark bulunmamıştır. Sonuç: İzole FKD hastalarında cerrahi güvenlidir ve yüksek nöbetsizlik oranı ile sonuçlanmıştır; ancak bazı hastalarda displastik alanın tamamen çıkarılması sonrasında hastaların hala neden nöbet geçirdiklerini açıklayamamamız nedeniyle cerrahi tamamen yeterli değilir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | TAHMAZOGLU B, Kartum T, Kemerdere R, SAYYAHMELLI S, Yeni S, Tanriverdi T (2020). Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era. , 86 - 92. 10.5152/cjm.2020.20009 |
| Chicago | TAHMAZOGLU BURAK,Kartum Tufan Agah,Kemerdere Rahsan,SAYYAHMELLI Sima,Yeni Seher Naz,Tanriverdi Taner Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era. (2020): 86 - 92. 10.5152/cjm.2020.20009 |
| MLA | TAHMAZOGLU BURAK,Kartum Tufan Agah,Kemerdere Rahsan,SAYYAHMELLI Sima,Yeni Seher Naz,Tanriverdi Taner Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era. , 2020, ss.86 - 92. 10.5152/cjm.2020.20009 |
| AMA | TAHMAZOGLU B,Kartum T,Kemerdere R,SAYYAHMELLI S,Yeni S,Tanriverdi T Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era. . 2020; 86 - 92. 10.5152/cjm.2020.20009 |
| Vancouver | TAHMAZOGLU B,Kartum T,Kemerdere R,SAYYAHMELLI S,Yeni S,Tanriverdi T Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era. . 2020; 86 - 92. 10.5152/cjm.2020.20009 |
| IEEE | TAHMAZOGLU B,Kartum T,Kemerdere R,SAYYAHMELLI S,Yeni S,Tanriverdi T "Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era." , ss.86 - 92, 2020. 10.5152/cjm.2020.20009 |
| ISNAD | TAHMAZOGLU, BURAK vd. "Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era". (2020), 86-92. https://doi.org/10.5152/cjm.2020.20009 |
| APA | TAHMAZOGLU B, Kartum T, Kemerdere R, SAYYAHMELLI S, Yeni S, Tanriverdi T (2020). Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era. Cerrahpaşa Medical Journal, 44(2), 86 - 92. 10.5152/cjm.2020.20009 |
| Chicago | TAHMAZOGLU BURAK,Kartum Tufan Agah,Kemerdere Rahsan,SAYYAHMELLI Sima,Yeni Seher Naz,Tanriverdi Taner Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era. Cerrahpaşa Medical Journal 44, no.2 (2020): 86 - 92. 10.5152/cjm.2020.20009 |
| MLA | TAHMAZOGLU BURAK,Kartum Tufan Agah,Kemerdere Rahsan,SAYYAHMELLI Sima,Yeni Seher Naz,Tanriverdi Taner Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era. Cerrahpaşa Medical Journal, vol.44, no.2, 2020, ss.86 - 92. 10.5152/cjm.2020.20009 |
| AMA | TAHMAZOGLU B,Kartum T,Kemerdere R,SAYYAHMELLI S,Yeni S,Tanriverdi T Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era. Cerrahpaşa Medical Journal. 2020; 44(2): 86 - 92. 10.5152/cjm.2020.20009 |
| Vancouver | TAHMAZOGLU B,Kartum T,Kemerdere R,SAYYAHMELLI S,Yeni S,Tanriverdi T Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era. Cerrahpaşa Medical Journal. 2020; 44(2): 86 - 92. 10.5152/cjm.2020.20009 |
| IEEE | TAHMAZOGLU B,Kartum T,Kemerdere R,SAYYAHMELLI S,Yeni S,Tanriverdi T "Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era." Cerrahpaşa Medical Journal, 44, ss.86 - 92, 2020. 10.5152/cjm.2020.20009 |
| ISNAD | TAHMAZOGLU, BURAK vd. "Seizure Outcome in Adult Patients with Isolated Focal Cortical Dysplasia in Modern Era". Cerrahpaşa Medical Journal 44/2 (2020), 86-92. https://doi.org/10.5152/cjm.2020.20009 |
