Posterior Segment Effects of Prostaglandin Analogues

SINIM ,Neslihan; KARAKÜÇÜK ,Sarper

doi:10.37845/ret.vit.2020.29.6

Neslihan SINIM

(Acıbadem Hastanesi, Göz Hastalıkları Bölümü, Kayseri, Türkiye)

Sarper KARAKÜÇÜK

(Anadolu Sağlık Merkezi, Göz Hastalıkları Anabilim Dalı, Kocaeli, Türkiye)

Retina-Vitreus

Yıl: 2020Cilt: 29Sayı: 1ISSN: 1300-1256 / 2717-7149Sayfa Aralığı: 30 - 34Metin Dili: İngilizce

DOI: https://doi.org/10.37845/ret.vit.2020.29.6

64 0

İngilizce

Posterior Segment Effects of Prostaglandin Analogues

Abstract: Purpose: Prostaglandin (PG) analogues are commonly used in the treatment of glaucoma. In this study, we aimed to investigate the posteriorsegment effects of the drug with long-term use of topical PG analogue monotherapy in patients with the diagnosis of primary open angle glaucoma(POAG).Materials and Methods: Patients diagnosed with POAG and treated for 1 to 3 years were included in the study. A total of 25 patients treatedwith latanoprost monotherapy formed the 1st group, 25 patients who received dorzolamide timolol combination monotherapy constitutedthe 2nd group, 25 patients with brimonidine monotherapy formed the 3rd group and 31 healthy volunteers made up the 4th group. Routineophthalmological examination, intraocular pressure (IOP) measurement and fundus examinations were performed thoroughly. Central macularand choroidal thicknesses were measured by optical coherence tomography (OCT).Results: There was no signifi cant difference in the mean macular thickness between the groups. The mean choroidal thickness was signifi cantlyhigher in patients using PG analogue than the other groups. None of the patients had intraocular infl ammation or cystoid macular edema (CME).Conclusion: The choroidal thickness was signifi cantly higher in the group receiving topical latanoprost monotherapy than the other groups.None of the patients had CME or infl ammation. PG analogue monotherapy can be used safely in POAG cases. PG analogue therapy should bekept in mind in clinical conditions where choroidal thickness is signifi cant.

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Belge Türü: DergiMakale Türü: Araştırma MakalesiErişim Formatı: Erişime Kapalı

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