Yıl: 2020 Cilt: 29 Sayı: 1 Sayfa Aralığı: 53 - 58 Metin Dili: İngilizce DOI: 10.37845/ret.vit.2020.29.10 İndeks Tarihi: 20-05-2021

The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion

Öz:
Purpose: To determine whether the disorganization of retinal inner layers (DRIL) on spectral-domain (SD) OCT is associated with visualoutcomes in eyes with treatment-naive branch retinal vein occlusion (BRVO).Materials and Methods: Thirty-two eyes of 32 treatment-naive patients with macular edema (ME) due to BRVO receiving three initialconsecutive monthly intravitreal ranibizumab were enrolled in this study. SD-OCT images from baseline, 3rd-month, 6th-month visits wereobserved and the presence and extent of DRIL was examined in the central 1-mm-wide foveal area. The effi cacy of the ranibizumab treatment,assessed by best-corrected visual acuity (BCVA), was evaluated at baseline, 3-month and 6-month visits.Results: A total of 32 eyes were included and DRIL was present in 14 (43.7%) eyes at baseline and 9 eyes (28.1%) at 6th month (P:0.01).Baseline DRIL was found to be associated with lower baseline BCVA (0.46 LogMAR for without DRIL vs. 0.65 LogMAR for DRIL, P: 0.013)and higher central retinal thickness (405.7 vs. 442.8, P: 0.016). Decrease in DRIL intensity at 3-month follow-up was associated with increasedvisual acuity (VA) at 6 months (P:0.001) and baseline DRIL extent was a predictive parameter for 6 months improvement in VA (p:0.01). SixmonthDRIL change was related to 6-month VA improvement (Pearson’s correlation test, r=0.726, P<0.001).Conclusion: In the present study, it was observed that the improvement of BCVA was found to be related to the decrease of the DRIL intensity.Therefore, the presence of DRIL at baseline and extent of DRIL following treatment might serve as a potential SD-OCT biomarker for patientswith ME secondary to treatment-naive-BRVO.
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Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik
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APA ÖZSAYGILI C, Duru N (2020). The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion. , 53 - 58. 10.37845/ret.vit.2020.29.10
Chicago ÖZSAYGILI CEMAL,Duru Necati The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion. (2020): 53 - 58. 10.37845/ret.vit.2020.29.10
MLA ÖZSAYGILI CEMAL,Duru Necati The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion. , 2020, ss.53 - 58. 10.37845/ret.vit.2020.29.10
AMA ÖZSAYGILI C,Duru N The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion. . 2020; 53 - 58. 10.37845/ret.vit.2020.29.10
Vancouver ÖZSAYGILI C,Duru N The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion. . 2020; 53 - 58. 10.37845/ret.vit.2020.29.10
IEEE ÖZSAYGILI C,Duru N "The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion." , ss.53 - 58, 2020. 10.37845/ret.vit.2020.29.10
ISNAD ÖZSAYGILI, CEMAL - Duru, Necati. "The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion". (2020), 53-58. https://doi.org/10.37845/ret.vit.2020.29.10
APA ÖZSAYGILI C, Duru N (2020). The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion. Retina-Vitreus, 29(1), 53 - 58. 10.37845/ret.vit.2020.29.10
Chicago ÖZSAYGILI CEMAL,Duru Necati The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion. Retina-Vitreus 29, no.1 (2020): 53 - 58. 10.37845/ret.vit.2020.29.10
MLA ÖZSAYGILI CEMAL,Duru Necati The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion. Retina-Vitreus, vol.29, no.1, 2020, ss.53 - 58. 10.37845/ret.vit.2020.29.10
AMA ÖZSAYGILI C,Duru N The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion. Retina-Vitreus. 2020; 29(1): 53 - 58. 10.37845/ret.vit.2020.29.10
Vancouver ÖZSAYGILI C,Duru N The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion. Retina-Vitreus. 2020; 29(1): 53 - 58. 10.37845/ret.vit.2020.29.10
IEEE ÖZSAYGILI C,Duru N "The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion." Retina-Vitreus, 29, ss.53 - 58, 2020. 10.37845/ret.vit.2020.29.10
ISNAD ÖZSAYGILI, CEMAL - Duru, Necati. "The Relationship Between Disorganitazion of The Retinal Inner Layers and Anti-VEGF Response in Branch Retinal Vein Occlusion". Retina-Vitreus 29/1 (2020), 53-58. https://doi.org/10.37845/ret.vit.2020.29.10