Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children
Yıl: 2021 Cilt: 26 Sayı: 1 Sayfa Aralığı: 183 - 188 Metin Dili: İngilizce DOI: 10.5578/flora.20219919 İndeks Tarihi: 21-05-2021
Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children
Öz: Introduction: Extended-spectrum β-lactamase-producing Escherichia coli or Klebsiella pneumoniae infections in the pediatric age group are mostly nosocomial infections. This study aimed to investigate the clinical pattern of extended-spectrum β-lactamase positive urinary tract infection and its seasonal distribution.Materials and Methods: We retrospectively reviewed the medical records of pediatric patients with extended-spectrum β-lactamases-positive UTI, who were followed-up in our clinic between June 2015 and June 2020.Results: One hundred-and-ten patients with ESBL-positive UTI and 231 with non-ESBL UTI were enrolled in this study. The rate of male sex in the ESBL group was significantly lower than that in the non-ESBL group (10.9% vs 27.2%, p= 0.001). The patients with ESBL were older than those in the non-ESBL group (81.3 ± 49.0 months vs 56.0 ± 47.2 months, p= 0.001). E. coli was the most iso-lated bacteria in both groups (68% and 70.5%, respectively). The rate of Klebsiella isolation in urine culture was significantly greater in the ESBL group than in the non-ESBL group (p= 0.04). The seasonal distribution of ESBL-positive patients was as follows: spring (18/16.4%), summer (25/22.7%), autumn (25/22.7%), and winter (42/38.2%).Conclusion: There is a substantially high rate of antibiotic resistance among patients with urinary tract infection in developing countries like Turkey. Moreover, we should be aware of the risk of ESBL-positive UTIs, especially in winter.
Anahtar Kelime: Çocuklarda Genişlemiş Spektrumlu Beta-laktamaz Üreten Bakterilerin Neden Olduğu İdrar Yolu İnfeksiyonlarının Klinik Paterni ve Mevsimsel Dağılımı
Öz: Giriş: Çocukluk yaş grubunda, genişlemiş spektrumlu β-laktamaz (GSBL) üreten Escherichia coli veya Klebsiella pneumoniae kaynaklı infeksiyonlar genelde hastane kaynaklıdır. Bu çalışmada GSBL (+) bakterilerle gelişen idrar yolu infeksiyonların klinik paterni ve mev-simsel dağılımını araştırmayı amaçladık.Materyal ve Metod: Haziran 2015 - Haziran 2020 tarihleri arasında kliniğimizde izlenen genişlemiş spektrumlu β-laktamaz pozitif bakterilerle gelişen idrar yolu infeksiyonu tanılı pediatrik hastaların tıbbi kayıtlarını geriye dönük olarak inceledik.Bulgular: Bu çalışmaya, GSBL (+) bakterilerle gelişen idrar yolu infeksiyonu olan 110 hasta ve GSBL negatif bakterilerle gelişen idrar yolu infeksiyonu olan 231 hasta dahil oldu. GSBL (+) grubundaki erkek cinsiyet oranı, GSBL (-) grupla karşılaştırıldığında anlamlı olarak daha düşüktü (%10.9’a karşı %27.2, p= 0.001). GSBL (+) hastalar, GSBL (-) olanlara göre daha yaşlıydı (81.3 ± 49.0 ay vs 560 ± 47.2 ay, p= 0.001). E. coli her iki grupta da en çok izole edilen bakteriydi (GSBL (+): %68, GSBL (-): %70.5). İdrar kültüründe Klebsiella izolasyon oranı GSBL (+) grubunda, GSBL (-) grubuna göre anlamlı olarak daha yüksekti (p= 0.04). GSBL (+) infeksiyonların, mevsimsel dağılımı şu şekildeydi: ilkbahar (18/%16.4), yaz (25/%22.7), sonbahar (25/%22.7) ve kış (42/%38.2).Sonuç: Türkiye gibi gelişmekte olan ülkelerde, idrar yolu infeksiyonu olan hastalar arasında oldukça yüksek oranda antibiyotik direnci vardır. Özellikle antibiyotik kullanımın arttığı kış aylarında GSBL (+) idrar yolu infeksiyonların farkında olunmalıdır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | TURSUN S, arslan z, alpcan a, GÜL S, Kandur Y (2021). Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children. , 183 - 188. 10.5578/flora.20219919 |
| Chicago | TURSUN SERKAN,arslan zeynep,alpcan aysegul,GÜL SERDAR,Kandur Yasar Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children. (2021): 183 - 188. 10.5578/flora.20219919 |
| MLA | TURSUN SERKAN,arslan zeynep,alpcan aysegul,GÜL SERDAR,Kandur Yasar Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children. , 2021, ss.183 - 188. 10.5578/flora.20219919 |
| AMA | TURSUN S,arslan z,alpcan a,GÜL S,Kandur Y Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children. . 2021; 183 - 188. 10.5578/flora.20219919 |
| Vancouver | TURSUN S,arslan z,alpcan a,GÜL S,Kandur Y Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children. . 2021; 183 - 188. 10.5578/flora.20219919 |
| IEEE | TURSUN S,arslan z,alpcan a,GÜL S,Kandur Y "Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children." , ss.183 - 188, 2021. 10.5578/flora.20219919 |
| ISNAD | TURSUN, SERKAN vd. "Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children". (2021), 183-188. https://doi.org/10.5578/flora.20219919 |
| APA | TURSUN S, arslan z, alpcan a, GÜL S, Kandur Y (2021). Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, 26(1), 183 - 188. 10.5578/flora.20219919 |
| Chicago | TURSUN SERKAN,arslan zeynep,alpcan aysegul,GÜL SERDAR,Kandur Yasar Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi 26, no.1 (2021): 183 - 188. 10.5578/flora.20219919 |
| MLA | TURSUN SERKAN,arslan zeynep,alpcan aysegul,GÜL SERDAR,Kandur Yasar Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, vol.26, no.1, 2021, ss.183 - 188. 10.5578/flora.20219919 |
| AMA | TURSUN S,arslan z,alpcan a,GÜL S,Kandur Y Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi. 2021; 26(1): 183 - 188. 10.5578/flora.20219919 |
| Vancouver | TURSUN S,arslan z,alpcan a,GÜL S,Kandur Y Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children. Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi. 2021; 26(1): 183 - 188. 10.5578/flora.20219919 |
| IEEE | TURSUN S,arslan z,alpcan a,GÜL S,Kandur Y "Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children." Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, 26, ss.183 - 188, 2021. 10.5578/flora.20219919 |
| ISNAD | TURSUN, SERKAN vd. "Clinical Patterns and Seasonal Distribution of Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Bacteria in Children". Flora İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi 26/1 (2021), 183-188. https://doi.org/10.5578/flora.20219919 |
