Yıl: 2021 Cilt: 4 Sayı: 2 Sayfa Aralığı: 148 - 153 Metin Dili: İngilizce DOI: 10.30714/j-ebr.2021267978 İndeks Tarihi: 19-06-2021

Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules

Öz:
Aim: Differentiation of thyroid nodules, either as benign or malignant, is a real diagnostic challenge.Inflammation has an important role in development of the malignancy. Therefore, inflammatory markers areassociated with malignant thyroid nodules. Platelet /lymphocyte ratio (PLR) is also one of the novelinflammatory indices derived from hemogram tests. We hypothesized whether PLR was associated withmalignant thyroid nodules. For this purpose, we compared PLR levels of the patients with benign thyroidnodules to the PLR of the subjects with malignant nodules.Methods: The subjects who visited outpatient internal medicine clinics of our institution with a diagnosis ofthyroid nodule were enrolled to the present retrospective study. According to the examination of the fine needleaspiration cytology (FNAC) specimen of the nodules, patients grouped into benign or malignant nodule groups.PLR of groups were compared.Results: Median PLR values of the benign and malignant thyroid nodule groups were 106 (48-432) % and 119(48-365) %, respectively (p=0.001). PLR value higher than 106% has 69% sensitivity and 51% specificity indetecting malignant nodules (AUC: 0.59, p=0.001, 95% CI: 0.54-0.65). PLR was positively correlated withTSH level (r=0.10, p=0.34).Conclusion: We suggest that elevated PLR could be an additional tool to differentiate malignant thyroidnodules from benign ones in supportive of sonography, scintigraphy and cytology.
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APA Bilgin S, kahveci g, Atak B, Kurtkulagi O, kosekli m (2021). Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules. , 148 - 153. 10.30714/j-ebr.2021267978
Chicago Bilgin Satılmış,kahveci gizem,Atak Burcin Meryem,Kurtkulagi Ozge,kosekli mehmet ali Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules. (2021): 148 - 153. 10.30714/j-ebr.2021267978
MLA Bilgin Satılmış,kahveci gizem,Atak Burcin Meryem,Kurtkulagi Ozge,kosekli mehmet ali Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules. , 2021, ss.148 - 153. 10.30714/j-ebr.2021267978
AMA Bilgin S,kahveci g,Atak B,Kurtkulagi O,kosekli m Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules. . 2021; 148 - 153. 10.30714/j-ebr.2021267978
Vancouver Bilgin S,kahveci g,Atak B,Kurtkulagi O,kosekli m Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules. . 2021; 148 - 153. 10.30714/j-ebr.2021267978
IEEE Bilgin S,kahveci g,Atak B,Kurtkulagi O,kosekli m "Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules." , ss.148 - 153, 2021. 10.30714/j-ebr.2021267978
ISNAD Bilgin, Satılmış vd. "Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules". (2021), 148-153. https://doi.org/10.30714/j-ebr.2021267978
APA Bilgin S, kahveci g, Atak B, Kurtkulagi O, kosekli m (2021). Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules. Experimental Biomedical Research, 4(2), 148 - 153. 10.30714/j-ebr.2021267978
Chicago Bilgin Satılmış,kahveci gizem,Atak Burcin Meryem,Kurtkulagi Ozge,kosekli mehmet ali Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules. Experimental Biomedical Research 4, no.2 (2021): 148 - 153. 10.30714/j-ebr.2021267978
MLA Bilgin Satılmış,kahveci gizem,Atak Burcin Meryem,Kurtkulagi Ozge,kosekli mehmet ali Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules. Experimental Biomedical Research, vol.4, no.2, 2021, ss.148 - 153. 10.30714/j-ebr.2021267978
AMA Bilgin S,kahveci g,Atak B,Kurtkulagi O,kosekli m Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules. Experimental Biomedical Research. 2021; 4(2): 148 - 153. 10.30714/j-ebr.2021267978
Vancouver Bilgin S,kahveci g,Atak B,Kurtkulagi O,kosekli m Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules. Experimental Biomedical Research. 2021; 4(2): 148 - 153. 10.30714/j-ebr.2021267978
IEEE Bilgin S,kahveci g,Atak B,Kurtkulagi O,kosekli m "Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules." Experimental Biomedical Research, 4, ss.148 - 153, 2021. 10.30714/j-ebr.2021267978
ISNAD Bilgin, Satılmış vd. "Platelet to lymphocyte ratio in differentiation of benign and malignant thyroid nodules". Experimental Biomedical Research 4/2 (2021), 148-153. https://doi.org/10.30714/j-ebr.2021267978