The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study
Yıl: 2021 Cilt: 18 Sayı: 1 Sayfa Aralığı: 30 - 36 Metin Dili: İngilizce DOI: 10.4274/tjod.galenos.2021.03073 İndeks Tarihi: 20-06-2021
The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study
Öz: Objective: To investigate whether embryo transfer affects pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection (IVF-ICSI) treatment.Materials and Methods: A total of 2,257 patients who underwent IVF-ICSI treatment between 2012 and 2017 were included in this study. Subjects werecategorized according to the embryo transfer technique that was required: group 1 (n=1,657) underwent easy transfer with a soft catheter; group 2 (n=548)received external guidance transfers; and group 3 (n=52) experienced difficult transfers with a stylet. Basal parameters, clinical and laboratory IVF-ICSIoutcomes, and clinical pregnancy rates (CPR) were compared between the groups.Results: There were no differences between the groups in terms of age, body mass index, smoking status, duration and etiology of infertility, baseline folliclestimulating hormone, luteinizing hormone, estradiol (E2), thyroid-stimulating hormone, prolactin levels, antral follicle count, duration of stimulation,stimulation protocol, total gonadotropin dose required, peak E2 levels, progesterone levels, and endometrial thickness on human chorionic gonadotropinadministration and transfer days (p>0.05). The numbers of oocytes retrieved, MII and 2PN, fertilization rate, day of embryo transfer, and CPRs were alsocomparable between the groups (p>0.05).Conclusion: Our data suggest that embryo transfer has no impact on pregnancy rates in patients who undergo IVF-ICSI treatment. Further studies withmore participants are required to elucidate this situation.
Anahtar Kelime: İn vitro fertilizasyon intrasitoplazmik sperm enjeksiyon sikluslarında embriyo transfer tekniğinin gebelik sonuçlarına etkisi
Öz: Amaç: İn vitro fertilizasyon-intrasitoplazmik sperm enjeksiyonu (IVF-ICSI) tedavisinde embriyo transfer tekniğinin gebelik oranları üzerinde bir etkisi olup olmadığını araştırmak. Gereç ve Yöntemler: 2012-2017 yılları arasında IVF-ICSI tedavisi gören toplam 2.257 hasta çalışmaya dahil edildi. Denekler embriyo transfer tekniğine göre üç gruba kategorize edildi: grup 1 (n=1657) yumuşak kateterle kolay transfer edilenler, grup 2 (n=548) dış harici kateterle transferleri edilenler, ve grup 3 (n=52) zor transfer yapılanlar. Gruplar arasında bazal parametreler, klinik ve laboratuvar IVF-ICSI sonuçları ve klinik gebelik oranları (KGO) karşılaştırıldı. Bulgular: Gruplar arasında yaş, vücut kitle indeksi, sigara içme durumu, infertilite süresi ve etiyolojisi, folikül uyarıcı hormon, lüteinizan hormon, östradiol (E2 ), tiroid uyarıcı hormon, prolaktin düzeyleri, antral folikül sayısı, infertilite süresi, stimülasyon günü, stimülasyon protokolü, gerekli toplam gonadotropin dozu, tepe E2seviyeleri, progesteron düzeyleri ve endometriyal kalınlık (human kayronik gonadotropini uygulanan gün) açısından fark yoktu (p>0,05). Alınan oosit sayısı, MII ve 2PN, döllenme oranı, embriyo transferi günü ve KGO’da gruplar arasında benzerdi (p>0,05). Sonuç: Verilerimiz, embriyo transfer tekniğinin IVF-ICSI tedavisi gören hastalarda gebelik oranları üzerinde hiçbir etkisi olmadığını göstermektedir. Bu durumu açıklamak için daha fazla katılımcıyla daha fazla çalışma yapılması gerekmektedir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Inal Z, Inal H (2021). The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study. , 30 - 36. 10.4274/tjod.galenos.2021.03073 |
| Chicago | Inal Zeynep Ozturk,Inal Hasan Ali The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study. (2021): 30 - 36. 10.4274/tjod.galenos.2021.03073 |
| MLA | Inal Zeynep Ozturk,Inal Hasan Ali The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study. , 2021, ss.30 - 36. 10.4274/tjod.galenos.2021.03073 |
| AMA | Inal Z,Inal H The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study. . 2021; 30 - 36. 10.4274/tjod.galenos.2021.03073 |
| Vancouver | Inal Z,Inal H The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study. . 2021; 30 - 36. 10.4274/tjod.galenos.2021.03073 |
| IEEE | Inal Z,Inal H "The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study." , ss.30 - 36, 2021. 10.4274/tjod.galenos.2021.03073 |
| ISNAD | Inal, Zeynep Ozturk - Inal, Hasan Ali. "The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study". (2021), 30-36. https://doi.org/10.4274/tjod.galenos.2021.03073 |
| APA | Inal Z, Inal H (2021). The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study. Turkish Journal of Obstetrics and Gynecology, 18(1), 30 - 36. 10.4274/tjod.galenos.2021.03073 |
| Chicago | Inal Zeynep Ozturk,Inal Hasan Ali The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study. Turkish Journal of Obstetrics and Gynecology 18, no.1 (2021): 30 - 36. 10.4274/tjod.galenos.2021.03073 |
| MLA | Inal Zeynep Ozturk,Inal Hasan Ali The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study. Turkish Journal of Obstetrics and Gynecology, vol.18, no.1, 2021, ss.30 - 36. 10.4274/tjod.galenos.2021.03073 |
| AMA | Inal Z,Inal H The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study. Turkish Journal of Obstetrics and Gynecology. 2021; 18(1): 30 - 36. 10.4274/tjod.galenos.2021.03073 |
| Vancouver | Inal Z,Inal H The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study. Turkish Journal of Obstetrics and Gynecology. 2021; 18(1): 30 - 36. 10.4274/tjod.galenos.2021.03073 |
| IEEE | Inal Z,Inal H "The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study." Turkish Journal of Obstetrics and Gynecology, 18, ss.30 - 36, 2021. 10.4274/tjod.galenos.2021.03073 |
| ISNAD | Inal, Zeynep Ozturk - Inal, Hasan Ali. "The effect of embryo transfer technique on pregnancy rates in in vitro fertilization-intracytoplasmic sperm injection cycles: A prospective cohort study". Turkish Journal of Obstetrics and Gynecology 18/1 (2021), 30-36. https://doi.org/10.4274/tjod.galenos.2021.03073 |
