Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs
Yıl: 2021 Cilt: 68 Sayı: 1 Sayfa Aralığı: 27 - 32 Metin Dili: İngilizce DOI: 10.33988/auvfd.680443 İndeks Tarihi: 28-06-2021
Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs
Öz: The aim of this study was to compare the postoperative analgesic effects of epidural bupivacaine, bupivacaine-butorphanoland bupivacaine-morphine in hind limb and pelvic orthopedic operations in dogs. Three groups each containing 10 dogs were formed. Through the lumbosacral space, group B was administered bupivacaine, 1 mg kg-1; group BB was administered bupivacaine, 1 mg kg-1and butorphanol, 0.25 mg kg-1; and group BM was administered bupivacaine, 1 mg kg-1and morphine, 0.1 mg kg-1. Anaesthesia was induced with diazepam (0.2 mg kg-1) and propofol (5 mg kg-1) and maintenance with isoflurane in oxygen.Pain assessment was performed with the University of Melbourne Pain Scale (UMPS) by a blinded observer. Plasma cortisol levels were measured preoperatively and postoperatively. Postoperative pain scores were significantly lower at 2 hours in the group BM,and at 8 and 12 hoursin the groups BB and BM compared to the group B (P=0.007). Group BM had a lower plasma cortisol level than the group B at 2 hours (P=0.002). Bupivacaine-butorphanol and bupivacaine-morphine use were shown to provide longer analgesia in the postoperative period; and the epidural administration of bupivacaine-butorphanol and bupivacaine-morphine was considered to be potentially useful in clinical practice.
Anahtar Kelime: Köpeklerde arka ekstremite ve pelvisin ortopedik operasyonlarında epidural bupivakain, bupivakain-butorfanol ve bupivakain-morfin uygulamasının postoperatif analjezi üzerine etkisi
Öz: Bu çalışmanın amacı, köpeklerde arka ekstremite ve pelvisin ortopedik operasyonlarında epidural bupivakain, bupivakain-butorfanol ve bupivakain-morfin uygulamasının postoperatifanaljezik etkilerinin karşılaştırılmasıdır. Her grupta 10 köpek olacak şekilde 3 farklı çalışma grubu oluşturuldu. Lumbosakral aralıktan grup B’ye bupivakain 1 mg kg-1; grup BB’ye bupivakain 1 mg kg-1ve butorfanol 0,25 mg kg-1; grup BM’ye ise bupivakain 1 mg kg-1ve morfin 0,1 mg kg-1uygulaması yapıldı. Anestezi indüksiyonu diazepam (0,2 mg kg-1)ve propofol (5 mg kg-1) ile yapıldıktan sonra idame izofloran ile sağlandı. Ağrının değerlendirilmesi kör gözlemci tarafından Melbourne Üniversitesi ağrı skalası (UMPS) kullanılarak yapılmıştır. Preoperatif ve postoperatif plazma kortizol seviyeleri ölçüldü. BM grubunun postoperatif 2. saatte plazma kortizol seviyesi B grubuna göre daha azolarak tespit edildi (P=0,002). Postoperatif ağrı skorları 2. saatte BM grubunda,8. ve 12. saatte BB ve BM grubunda B grubuna göre daha az olarak tespit edildi (P=0,007). Çalışma sonucunda bupivakain-butorfanol ve bupivakain-morfin kullanımının postoperatif dönemde sadece bupivakain kullanımına göre daha uzun süreli analjezi sağladığı ve bupivakain-morfine göre daha düşük yan etkiye sahip olan bupivakain-butorfanolun epidural uygulamasının pratikte kullanılmasının faydalı olabileceği düşünülmüştür.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | KARSLI B, Pekcan Z, KUMANDAS A, KÜRÜM B, Cinar M (2021). Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs. , 27 - 32. 10.33988/auvfd.680443 |
| Chicago | KARSLI BIRKAN,Pekcan Zeynep,KUMANDAS ALI,KÜRÜM BARIS,Cinar Miyase Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs. (2021): 27 - 32. 10.33988/auvfd.680443 |
| MLA | KARSLI BIRKAN,Pekcan Zeynep,KUMANDAS ALI,KÜRÜM BARIS,Cinar Miyase Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs. , 2021, ss.27 - 32. 10.33988/auvfd.680443 |
| AMA | KARSLI B,Pekcan Z,KUMANDAS A,KÜRÜM B,Cinar M Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs. . 2021; 27 - 32. 10.33988/auvfd.680443 |
| Vancouver | KARSLI B,Pekcan Z,KUMANDAS A,KÜRÜM B,Cinar M Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs. . 2021; 27 - 32. 10.33988/auvfd.680443 |
| IEEE | KARSLI B,Pekcan Z,KUMANDAS A,KÜRÜM B,Cinar M "Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs." , ss.27 - 32, 2021. 10.33988/auvfd.680443 |
| ISNAD | KARSLI, BIRKAN vd. "Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs". (2021), 27-32. https://doi.org/10.33988/auvfd.680443 |
| APA | KARSLI B, Pekcan Z, KUMANDAS A, KÜRÜM B, Cinar M (2021). Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs. Ankara Üniversitesi Veteriner Fakültesi Dergisi, 68(1), 27 - 32. 10.33988/auvfd.680443 |
| Chicago | KARSLI BIRKAN,Pekcan Zeynep,KUMANDAS ALI,KÜRÜM BARIS,Cinar Miyase Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs. Ankara Üniversitesi Veteriner Fakültesi Dergisi 68, no.1 (2021): 27 - 32. 10.33988/auvfd.680443 |
| MLA | KARSLI BIRKAN,Pekcan Zeynep,KUMANDAS ALI,KÜRÜM BARIS,Cinar Miyase Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs. Ankara Üniversitesi Veteriner Fakültesi Dergisi, vol.68, no.1, 2021, ss.27 - 32. 10.33988/auvfd.680443 |
| AMA | KARSLI B,Pekcan Z,KUMANDAS A,KÜRÜM B,Cinar M Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs. Ankara Üniversitesi Veteriner Fakültesi Dergisi. 2021; 68(1): 27 - 32. 10.33988/auvfd.680443 |
| Vancouver | KARSLI B,Pekcan Z,KUMANDAS A,KÜRÜM B,Cinar M Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs. Ankara Üniversitesi Veteriner Fakültesi Dergisi. 2021; 68(1): 27 - 32. 10.33988/auvfd.680443 |
| IEEE | KARSLI B,Pekcan Z,KUMANDAS A,KÜRÜM B,Cinar M "Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs." Ankara Üniversitesi Veteriner Fakültesi Dergisi, 68, ss.27 - 32, 2021. 10.33988/auvfd.680443 |
| ISNAD | KARSLI, BIRKAN vd. "Effects of epidural bupivacaine, bupivacaine-butorphanol and bupivacaine-morphine on postoperative analgesia for hind limb and pelvic orthopedic operations in dogs". Ankara Üniversitesi Veteriner Fakültesi Dergisi 68/1 (2021), 27-32. https://doi.org/10.33988/auvfd.680443 |
