Yıl: 2021 Cilt: 53 Sayı: 1 Sayfa Aralığı: 22 - 27 Metin Dili: İngilizce DOI: 10.5152/eurasianjmed.2021.20035 İndeks Tarihi: 28-06-2021

Destructive Effects of Acidic Blood on the Intestines: Experimental Study

Öz:
Objective: This study aimed to investigate the destructive effects of acidic blood on the intestinal structures,which has been reported as the most hazardous biochemical result of vagosympathetic autonomic imbalances in intensive care unit patients with subarachnoid hemorrhage (SAH).Materials and Methods: In total, 27 hybrid rabbits were used; 5 rabbits were used as a control group, 7 asthe SHAM group into whom 1 cc saline was injected into the cisterna magna, and the remaining 15 wereused as the study group. These animals received 1 cc of autologous arterial blood injection into the cisternamagna to create the SAH group. Blood pH values were recorded before, during, and after the experimentalprocedures. Computed tomography was performed to examine the intestinal morphology. Normal and degenerated epithelial cell densities of the intestine were estimated by stereological methods. The relationshipbetween pH values and intestinal tissue changes was analyzed statistically using the Mann–Whitney U test.Results: The mean blood pH values were 7.364±0.042 in the control group, 7.326±0.059 in the SHAMgroup, and 7.23±0.021 in the study group. Intestinal epithelial cell injury, desquamation of villus, and cell losswere observed. It is observed that the number of degenerated epithelial cells, fragmented villi numbers, andvacuoles significantly increased in the study group (p<0.05).Conclusion: Acidotic intestinal injury secondary to blood pH changes following SAH may be considered as ageneralized and dangerous complication with their multiorgan insuficiency effect.
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APA çağlar ö, karadeniz e, fırıncı b, AYDIN M, Ceylan O, Aydin M, Kantarci M (2021). Destructive Effects of Acidic Blood on the Intestines: Experimental Study. , 22 - 27. 10.5152/eurasianjmed.2021.20035
Chicago çağlar özgür,karadeniz erdem,fırıncı binali,AYDIN Muhammed Enes,Ceylan Onur,Aydin Mehmet Dumlu,Kantarci Mecit Destructive Effects of Acidic Blood on the Intestines: Experimental Study. (2021): 22 - 27. 10.5152/eurasianjmed.2021.20035
MLA çağlar özgür,karadeniz erdem,fırıncı binali,AYDIN Muhammed Enes,Ceylan Onur,Aydin Mehmet Dumlu,Kantarci Mecit Destructive Effects of Acidic Blood on the Intestines: Experimental Study. , 2021, ss.22 - 27. 10.5152/eurasianjmed.2021.20035
AMA çağlar ö,karadeniz e,fırıncı b,AYDIN M,Ceylan O,Aydin M,Kantarci M Destructive Effects of Acidic Blood on the Intestines: Experimental Study. . 2021; 22 - 27. 10.5152/eurasianjmed.2021.20035
Vancouver çağlar ö,karadeniz e,fırıncı b,AYDIN M,Ceylan O,Aydin M,Kantarci M Destructive Effects of Acidic Blood on the Intestines: Experimental Study. . 2021; 22 - 27. 10.5152/eurasianjmed.2021.20035
IEEE çağlar ö,karadeniz e,fırıncı b,AYDIN M,Ceylan O,Aydin M,Kantarci M "Destructive Effects of Acidic Blood on the Intestines: Experimental Study." , ss.22 - 27, 2021. 10.5152/eurasianjmed.2021.20035
ISNAD çağlar, özgür vd. "Destructive Effects of Acidic Blood on the Intestines: Experimental Study". (2021), 22-27. https://doi.org/10.5152/eurasianjmed.2021.20035
APA çağlar ö, karadeniz e, fırıncı b, AYDIN M, Ceylan O, Aydin M, Kantarci M (2021). Destructive Effects of Acidic Blood on the Intestines: Experimental Study. Eurasian Journal of Medicine, 53(1), 22 - 27. 10.5152/eurasianjmed.2021.20035
Chicago çağlar özgür,karadeniz erdem,fırıncı binali,AYDIN Muhammed Enes,Ceylan Onur,Aydin Mehmet Dumlu,Kantarci Mecit Destructive Effects of Acidic Blood on the Intestines: Experimental Study. Eurasian Journal of Medicine 53, no.1 (2021): 22 - 27. 10.5152/eurasianjmed.2021.20035
MLA çağlar özgür,karadeniz erdem,fırıncı binali,AYDIN Muhammed Enes,Ceylan Onur,Aydin Mehmet Dumlu,Kantarci Mecit Destructive Effects of Acidic Blood on the Intestines: Experimental Study. Eurasian Journal of Medicine, vol.53, no.1, 2021, ss.22 - 27. 10.5152/eurasianjmed.2021.20035
AMA çağlar ö,karadeniz e,fırıncı b,AYDIN M,Ceylan O,Aydin M,Kantarci M Destructive Effects of Acidic Blood on the Intestines: Experimental Study. Eurasian Journal of Medicine. 2021; 53(1): 22 - 27. 10.5152/eurasianjmed.2021.20035
Vancouver çağlar ö,karadeniz e,fırıncı b,AYDIN M,Ceylan O,Aydin M,Kantarci M Destructive Effects of Acidic Blood on the Intestines: Experimental Study. Eurasian Journal of Medicine. 2021; 53(1): 22 - 27. 10.5152/eurasianjmed.2021.20035
IEEE çağlar ö,karadeniz e,fırıncı b,AYDIN M,Ceylan O,Aydin M,Kantarci M "Destructive Effects of Acidic Blood on the Intestines: Experimental Study." Eurasian Journal of Medicine, 53, ss.22 - 27, 2021. 10.5152/eurasianjmed.2021.20035
ISNAD çağlar, özgür vd. "Destructive Effects of Acidic Blood on the Intestines: Experimental Study". Eurasian Journal of Medicine 53/1 (2021), 22-27. https://doi.org/10.5152/eurasianjmed.2021.20035