Objective: Acute gastroenteritis is one of the major cause of mortality and morbidity in childhood. Differantiating the pathogen is important for infection control and choosing appropriate treatment in children who present to emergency department with acute gastroenteritis. Beside the pathogen and clinical status of child and social status of the family is also important for the treatment and follow-up plan in pediatric Emergency department, especially during the increased periods of acute gastroenteritis epidemies. In this study beside the pathogens of gastroenteritis patients’ sociodemographic and clinical status and their relationship with C Reactive Protein CRP were investigated. Material and Methods: A total of 400 patients between the ages of 2 months and 14 years who had applied to pediatric emergency department with the complaint of acute gastroenteritis were admitted to the study. CRP was quantitatively determined by nephelometric method in patients’ serums; Values above 1 mg / dl and above were considered positive. In addition, whole blood count and serum electrolyte levels, direct microscopic examination of leukocytes and parasites of stool were investigated, fast antigen test method of Rotavirus Adenovirus antigen and also stool culture was done. Results: 46% of the patients had low socioeconomic status, 29% had a crowded family, 23% had a simultaneous gastroenteritis in the family, and 16% of them were attending nursery or school. CRP positiveness was significantly higher in the groups of crowded family (p = 0.043) and in the nursery / school (p = 0.006). CRP levels were found to be high in patients with nausea, vomiting, fever and bloody stool. (all p = 0.001) No pathogenic microorganism was detected in gaita cultures, CRP positivity was significantly high in patients with fever and blood stool and leukocytosis. In addition, CRP positiveness was significantly higher in Rotavirus, Adenovirus, and both positive cases (p = 0.02, p = 0.003, p = 0.0001, respectively). The rate of Rotavirus and Adenovirus positivity was high in hospitalized patients rather than not hospitalized. Conclusion: In conclusion, although CRP is frequently used as a bacterial marker, in addition to bacterial infections it may increase also in viral infections like patients who presented to the pediatric emergency department with gastroenteritis symptoms.