Yıl: 2021 Cilt: 28 Sayı: 2 Sayfa Aralığı: 336 - 342 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2020.09.999 İndeks Tarihi: 28-06-2021

The value of laboratory markers in the differential diagnosis of acute vestibular syndrome

Öz:
Aim: Stroke is one of the leading and most challenging problems in distinguishing between central and peripheral causes of acute vestibular syndrome. This study aims to evaluate the potential utility of neutrophil to lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and gamma-glutamyl transferase (GGT) levels in the differential diagnosis of acute vestibular syndrome. Materials and Methods: This retrospective study included 152 patients diagnosed with vestibular neuritis (VN) and posterior circulation ischemic stroke (PCIS) within the scope of the isolated acute vestibular syndrome (AVS: vertigo, nystagmus, nausea-vomiting, postural instability, and intolerance of head movements). Of all these patients, we listed the ones having normal MRI findings and diagnosed with VN in the department of otorhinolaryngology. The diagnosis of stroke was made through neuroimaging methods (CT and MRI). NLR and GGT levels were compared among the patients diagnosed with VN and PCIS. Results: GGT, NLR, PLR levels were significantly higher in the patients with the PCIS group (p<0.05). The AUC (area under the curve) and optimal cutoff values for NLR, PLR, and GGT were analyzed by ROC analysis. According to these results, the diagnostic value of NLR was higher in predicting stroke (AUC: 0.741; 95%CI: 0.652-0.829, p<0.001)Conclusion: As a result, NLR, GGT, and PLR can be useful biomarkers for deciding in favor of stroke in the differential diagnosis of VN.
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APA Gökçen E, Demir B, Savrun Ş (2021). The value of laboratory markers in the differential diagnosis of acute vestibular syndrome. , 336 - 342. 10.5455/annalsmedres.2020.09.999
Chicago Gökçen Emre,Demir Bilgehan,Savrun Şeyda Tuba The value of laboratory markers in the differential diagnosis of acute vestibular syndrome. (2021): 336 - 342. 10.5455/annalsmedres.2020.09.999
MLA Gökçen Emre,Demir Bilgehan,Savrun Şeyda Tuba The value of laboratory markers in the differential diagnosis of acute vestibular syndrome. , 2021, ss.336 - 342. 10.5455/annalsmedres.2020.09.999
AMA Gökçen E,Demir B,Savrun Ş The value of laboratory markers in the differential diagnosis of acute vestibular syndrome. . 2021; 336 - 342. 10.5455/annalsmedres.2020.09.999
Vancouver Gökçen E,Demir B,Savrun Ş The value of laboratory markers in the differential diagnosis of acute vestibular syndrome. . 2021; 336 - 342. 10.5455/annalsmedres.2020.09.999
IEEE Gökçen E,Demir B,Savrun Ş "The value of laboratory markers in the differential diagnosis of acute vestibular syndrome." , ss.336 - 342, 2021. 10.5455/annalsmedres.2020.09.999
ISNAD Gökçen, Emre vd. "The value of laboratory markers in the differential diagnosis of acute vestibular syndrome". (2021), 336-342. https://doi.org/10.5455/annalsmedres.2020.09.999
APA Gökçen E, Demir B, Savrun Ş (2021). The value of laboratory markers in the differential diagnosis of acute vestibular syndrome. Annals of Medical Research, 28(2), 336 - 342. 10.5455/annalsmedres.2020.09.999
Chicago Gökçen Emre,Demir Bilgehan,Savrun Şeyda Tuba The value of laboratory markers in the differential diagnosis of acute vestibular syndrome. Annals of Medical Research 28, no.2 (2021): 336 - 342. 10.5455/annalsmedres.2020.09.999
MLA Gökçen Emre,Demir Bilgehan,Savrun Şeyda Tuba The value of laboratory markers in the differential diagnosis of acute vestibular syndrome. Annals of Medical Research, vol.28, no.2, 2021, ss.336 - 342. 10.5455/annalsmedres.2020.09.999
AMA Gökçen E,Demir B,Savrun Ş The value of laboratory markers in the differential diagnosis of acute vestibular syndrome. Annals of Medical Research. 2021; 28(2): 336 - 342. 10.5455/annalsmedres.2020.09.999
Vancouver Gökçen E,Demir B,Savrun Ş The value of laboratory markers in the differential diagnosis of acute vestibular syndrome. Annals of Medical Research. 2021; 28(2): 336 - 342. 10.5455/annalsmedres.2020.09.999
IEEE Gökçen E,Demir B,Savrun Ş "The value of laboratory markers in the differential diagnosis of acute vestibular syndrome." Annals of Medical Research, 28, ss.336 - 342, 2021. 10.5455/annalsmedres.2020.09.999
ISNAD Gökçen, Emre vd. "The value of laboratory markers in the differential diagnosis of acute vestibular syndrome". Annals of Medical Research 28/2 (2021), 336-342. https://doi.org/10.5455/annalsmedres.2020.09.999