Yıl: 2021 Cilt: 28 Sayı: 1 Sayfa Aralığı: 90 - 94 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2020.10 İndeks Tarihi: 28-06-2021

Evaluation of growth after liver transplantation in a group of Turkish pediatric patients

Öz:
Aim: Growth failure is considered as an important predictor of negative outcomes after liver transplantation (LT). In our study we aimed to evaluate the growth of liver transplanted children both at the time of LT and on follow-up and to determine factors which are effective on growth. Materials and Methods: Seventy nine children were included in the study. Evaluation of growth just before the LT and post-LT 6th month,1st,2nd and 3rd years was done by using weight for age Z (WAZ) and height for age Z scores (HAZ). Results: Sixteen (20.3%) patients had HAZ score<-2 SD (standard deviation) and 13 (16.5%) had WAZ score <-2 SD. Stunting was detected in 17.8% and 23.5% of children with acute liver failure and chronic liver disease, underweight was present in 8.9% and26.5%of them, respectively (p=0.52 and p=0.037, respectively). Both HAZ and WAZ scores increased after LT, especially in the first year. Not mean pre-LT WAZ but mean HAZ score was lower in children who died on follow-up (p=0.023).Conclusion: Malnutrition before LT is a common problem in children. As stunting is a factor that reduces the chance of survival after LT, prevention and correction is very important.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Barshes NR, Chang IF, Karpen SJ, et al. Impact of pretransplant growth retardation in pediatric liver transplantation. J Pediatr Gastroenterol Nutr 2006: 43:89-94.
  • 2. Goulet OJ, De Ville De Goyet J, Otte JB, et al. Preoperative nutritional evaluation and support for liver transplantation in children. Transplant Proc 1987:19:3249-255.
  • 3. Baran M, Cakir M, Unal F, et al. Evaluation of growth after liver transplantation in Turkish children. Dig Dis Sci 2011:56:3343-349.
  • 4. Pawlowska J, Socha P, Jankowska I. Factors affecting catch-up growth after liver transplantation in children with cholestatic liver diseases. Ann Transplant 2010:15:72-76.
  • 5. Cabré E, Gassull MA. Nutritional aspects of liver disease and transplantation. Curr Opin Clin Nutr Metab Care 2001:4:581-589.
  • 6. Ramaccioni V, Soriano HE, Arumugam R, et al.. Nutritional aspects of chronic liver disease and liver transplantation in children. J Pediatr Gastroenterol Nutr 2000:30:361-7.
  • 7. Yuksekkaya HA, Cakir M, Tumgor G, et al. Nutritional status of infants with neonatal cholestasis. Dig Dis Sci 2008:53:803-8.
  • 8. Evans IV, Belle SH, Wei Y, et al. National Institute of Diabetes and Digestive and Kidney Diseases Liver Transplantation Database Team. Posttransplantation growth among pediatric recipients of liver transplantation. Pediatr Transplant 2005:9:480- 5.
  • 9. Orii T, Ohkohchi N, Koyamada N, et al. Growth of pediatric patients with biliary atresia after liver transplantation: influence of age at transplantation and steroid administration. Transplant Proc 2000:32:2210-2.
  • 10. De Palo EF, Bassanello M, Lancerin F, et al. GH/IGF system, cirrhosis and liver transplantation. Clin Chim Acta 2001:310:31-7.
  • 11. Baruch Y. The liver: a large endocrine gland. J Hepatol 2000:32:505-7.
  • 12. Neyzi O, Bundak R, Gökçay G, et al. Reference Values for Weight, Height, Head Circumference, and Body Mass Index in Turkish Children. J Clin Res Pediatr Endocrinol. 2015;7:280-93.
  • 13. Alonso G, Duca P, Pasqualini T, et al. Evaluation of catch-up growth after liver transplantation in children with biliary atresia. Pediatr Transplant 2004:8:255-9.
  • 14. Bartosh SM, Thomas SE, Sutton MM, et al. Whitington PF. Linear growth after pediatric liver transplantation. J Pediatr 1999:135:624-31.
  • 15. Codoner-Franch P, Bernard O, Alvarez F. Long-term follow-up of growth in height after successful liver transplantation. J Pediatr 1994:124:368-73.
  • 16. Mc Diarmid S, Gornbein J, Desilva P. Factors affecting growth after pediatric liver transplantation. Transplantation 1999:67:400-411.
  • 17. http://www.hips.hacettepe.edu.tr/tnsa2013/rapor/ TDHS_2013_main.report.pdf last accessed: February 4th, 2016.
  • 18. Park SJ, Rim SH, Kim KM, et al. Long-term growth of pediatric patients following living-donor liver transplantation. J Korean Med Sci 2005:20:835-40.
  • 19. Scheenstra R, Gerver WJ, Odink RJ, et al. Growth and final height after liver transplantation during childhood. J Pediatr Gastroenterol Nutr 2008:47:165- 71.
  • 20. Viner RM, Forton JT, Cole TJ, et al. Growth of longterm survivors of liver transplantation. Arch Dis Child 1999:80:235-40.
  • 21. Renz JF, De Roos M, Rosenthal P, et al. Posttransplantation growth in pediatric liver recipients. Liver Transpl 2001:7:1040-55.
  • 22. Bucuvalas JC, Ryckman FC, Atherton H, et al. Predictors of cost of liver transplantation in children: a single center study. J Pediatr 2001:139:66-74.
  • 23. Bucuvalas JC, Zeng L, Anand R; Studies of Pediatric Liver Transplantation Research Group. Predictors of length of stay for pediatric liver
APA VAROL F, Selimoglu M, Güngör Ş, Yilmaz S (2021). Evaluation of growth after liver transplantation in a group of Turkish pediatric patients. , 90 - 94. 10.5455/annalsmedres.2020.10
Chicago VAROL FATMA,Selimoglu Mukadder Ayse,Güngör Şükrü,Yilmaz Sezai Evaluation of growth after liver transplantation in a group of Turkish pediatric patients. (2021): 90 - 94. 10.5455/annalsmedres.2020.10
MLA VAROL FATMA,Selimoglu Mukadder Ayse,Güngör Şükrü,Yilmaz Sezai Evaluation of growth after liver transplantation in a group of Turkish pediatric patients. , 2021, ss.90 - 94. 10.5455/annalsmedres.2020.10
AMA VAROL F,Selimoglu M,Güngör Ş,Yilmaz S Evaluation of growth after liver transplantation in a group of Turkish pediatric patients. . 2021; 90 - 94. 10.5455/annalsmedres.2020.10
Vancouver VAROL F,Selimoglu M,Güngör Ş,Yilmaz S Evaluation of growth after liver transplantation in a group of Turkish pediatric patients. . 2021; 90 - 94. 10.5455/annalsmedres.2020.10
IEEE VAROL F,Selimoglu M,Güngör Ş,Yilmaz S "Evaluation of growth after liver transplantation in a group of Turkish pediatric patients." , ss.90 - 94, 2021. 10.5455/annalsmedres.2020.10
ISNAD VAROL, FATMA vd. "Evaluation of growth after liver transplantation in a group of Turkish pediatric patients". (2021), 90-94. https://doi.org/10.5455/annalsmedres.2020.10
APA VAROL F, Selimoglu M, Güngör Ş, Yilmaz S (2021). Evaluation of growth after liver transplantation in a group of Turkish pediatric patients. Annals of Medical Research, 28(1), 90 - 94. 10.5455/annalsmedres.2020.10
Chicago VAROL FATMA,Selimoglu Mukadder Ayse,Güngör Şükrü,Yilmaz Sezai Evaluation of growth after liver transplantation in a group of Turkish pediatric patients. Annals of Medical Research 28, no.1 (2021): 90 - 94. 10.5455/annalsmedres.2020.10
MLA VAROL FATMA,Selimoglu Mukadder Ayse,Güngör Şükrü,Yilmaz Sezai Evaluation of growth after liver transplantation in a group of Turkish pediatric patients. Annals of Medical Research, vol.28, no.1, 2021, ss.90 - 94. 10.5455/annalsmedres.2020.10
AMA VAROL F,Selimoglu M,Güngör Ş,Yilmaz S Evaluation of growth after liver transplantation in a group of Turkish pediatric patients. Annals of Medical Research. 2021; 28(1): 90 - 94. 10.5455/annalsmedres.2020.10
Vancouver VAROL F,Selimoglu M,Güngör Ş,Yilmaz S Evaluation of growth after liver transplantation in a group of Turkish pediatric patients. Annals of Medical Research. 2021; 28(1): 90 - 94. 10.5455/annalsmedres.2020.10
IEEE VAROL F,Selimoglu M,Güngör Ş,Yilmaz S "Evaluation of growth after liver transplantation in a group of Turkish pediatric patients." Annals of Medical Research, 28, ss.90 - 94, 2021. 10.5455/annalsmedres.2020.10
ISNAD VAROL, FATMA vd. "Evaluation of growth after liver transplantation in a group of Turkish pediatric patients". Annals of Medical Research 28/1 (2021), 90-94. https://doi.org/10.5455/annalsmedres.2020.10