Yıl: 2021 Cilt: 37 Sayı: 1 Sayfa Aralığı: 20 - 26 Metin Dili: İngilizce DOI: 10.4274/eamr.galenos.2020.65002 İndeks Tarihi: 28-06-2021

Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels

Öz:
Objective: The aim of this study was to determine the effects of vitamin D supplementation on kidney function, blood concentrations of25-hydroxyvitamin D, and parathyroid hormone levels.Methods: The 25-hydroxyvitamin D levels of approximately 4,000 participants between the ages of 18 and 75 years were investigatedretrospectively. Inclusion criteria included screening 25-hydroxyvitamin D <10 ng/mL at the local clinical laboratory. This study required thecontrol of blood parameters at 2 and 6 weeks. Because of this, 120 patients were chosen and categorized according to treatment procedures.The first group of participants was prescribed a fixed dose of 300,000 IU oral vitamin D filled at local clinical pharmacies. The second group ofparticipants was prescribed a fixed dose of 300,000 IU parenteral vitamin D filled at local clinical pharmacies. The last group of participantswas prescribed a fixed dose of 50,000 IU once weekly oral vitamin D once weekly for six weeks filled at local clinical pharmacies. Vitamin Dvalues and biochemical laboratory parameters were recorded and were compared between groups using statistical methods.Results: The treatment regimens with 25-hydroxyvitamin D3 were divided equally among three patient groups (n1=40, n2=40, n3=40). Thefindings were that 25-hydroxyvitamin D levels changes in the first (p=0.001) and third groups (p=0.001) were greater than the second group(p<0.01).Conclusion: These effects occur with significant changes in oral vitamin D supplementation rather than when vitamin D is administeredparenterally.
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APA ATAR S, demirhan e, Hüner B, AYDIN T, Dikker O, Kuru O (2021). Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels. , 20 - 26. 10.4274/eamr.galenos.2020.65002
Chicago ATAR SEVGI,demirhan esma,Hüner Berrin,AYDIN Tuğba,Dikker Okan,Kuru Omer Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels. (2021): 20 - 26. 10.4274/eamr.galenos.2020.65002
MLA ATAR SEVGI,demirhan esma,Hüner Berrin,AYDIN Tuğba,Dikker Okan,Kuru Omer Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels. , 2021, ss.20 - 26. 10.4274/eamr.galenos.2020.65002
AMA ATAR S,demirhan e,Hüner B,AYDIN T,Dikker O,Kuru O Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels. . 2021; 20 - 26. 10.4274/eamr.galenos.2020.65002
Vancouver ATAR S,demirhan e,Hüner B,AYDIN T,Dikker O,Kuru O Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels. . 2021; 20 - 26. 10.4274/eamr.galenos.2020.65002
IEEE ATAR S,demirhan e,Hüner B,AYDIN T,Dikker O,Kuru O "Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels." , ss.20 - 26, 2021. 10.4274/eamr.galenos.2020.65002
ISNAD ATAR, SEVGI vd. "Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels". (2021), 20-26. https://doi.org/10.4274/eamr.galenos.2020.65002
APA ATAR S, demirhan e, Hüner B, AYDIN T, Dikker O, Kuru O (2021). Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels. European Archives of Medical Research, 37(1), 20 - 26. 10.4274/eamr.galenos.2020.65002
Chicago ATAR SEVGI,demirhan esma,Hüner Berrin,AYDIN Tuğba,Dikker Okan,Kuru Omer Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels. European Archives of Medical Research 37, no.1 (2021): 20 - 26. 10.4274/eamr.galenos.2020.65002
MLA ATAR SEVGI,demirhan esma,Hüner Berrin,AYDIN Tuğba,Dikker Okan,Kuru Omer Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels. European Archives of Medical Research, vol.37, no.1, 2021, ss.20 - 26. 10.4274/eamr.galenos.2020.65002
AMA ATAR S,demirhan e,Hüner B,AYDIN T,Dikker O,Kuru O Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels. European Archives of Medical Research. 2021; 37(1): 20 - 26. 10.4274/eamr.galenos.2020.65002
Vancouver ATAR S,demirhan e,Hüner B,AYDIN T,Dikker O,Kuru O Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels. European Archives of Medical Research. 2021; 37(1): 20 - 26. 10.4274/eamr.galenos.2020.65002
IEEE ATAR S,demirhan e,Hüner B,AYDIN T,Dikker O,Kuru O "Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels." European Archives of Medical Research, 37, ss.20 - 26, 2021. 10.4274/eamr.galenos.2020.65002
ISNAD ATAR, SEVGI vd. "Effects of Oral or Parenteral Vitamin D Supplementation on Kidney Function, Blood Concentrations of 25-Hydroxyvitamin D, and Parathyroid Hormone Levels". European Archives of Medical Research 37/1 (2021), 20-26. https://doi.org/10.4274/eamr.galenos.2020.65002