Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy
Yıl: 2020 Cilt: 29 Sayı: 3 Sayfa Aralığı: 112 - 117 Metin Dili: İngilizce DOI: 10.4274/mirt.galenos.2020.88261 İndeks Tarihi: 30-06-2021
Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy
Öz: Objectives: Several studies demonstrate the relationship between coronary artery disease and inflammatory parameters. Nevertheless, there ispaucity of data regarding the role of high sensitivity (hs)-C-reactive protein (CRP) to albumin ratio (CAR) in patients with ischemia on gated singlephoton emission tomography (SPECT) myocardial perfusion imaging (MPI). This study was aimed at demonstrating the relationship between CARand the occurrence of ischemia on gated SPECT MPI.Methods: We retrospectively evaluated 2.048 referred patients for gated SPECT MPI from a cardiology outpatient clinic between October 2017and June 2019. After applying exclusion criteria and measuring serum CRP and albumin levels, we included 126 patients in the study. We thenclassified subjects into different groups according to the absence or presence of ischemia on gated SPECT MPI.Results: According to laboratory findings, hs-CRP and CAR were significantly higher in the ischemia group, while the serum albumin was significantlylower in ischemia group (p<0.05 for each). The independent predictors of presence of ischemia in multivariate analysis were hypertension andCAR (CAR; odds ratio: 5.720, 95% confidence interval: 2.697-12.133, p<0.001). The optimal value of CAR for presence of ischemia was 0.96 with76% sensitivity and 71% specificity.Conclusion: We found CAR values as a predictor for ischemia before MPI
Anahtar Kelime: C-reaktif Protein/Albümin Oranının Miyokardiyal Perfüzyon Sintigrafisinde İskemi Öngörmedeki Rolü
Öz: Amaç: Birçok çalışmada, koroner arter hastalığı ile enflamatuvar parametreler arasında ilişki bulunduğu gösterilmiştir. Bununla birlikte, tek foton emisyon tomografisi (SPECT) miyokard perfüzyon görüntülemesinde (MPI) iskemi bulunan hastalardaki C-reaktif proteinin (CRP)/albümin oranının (CAR) rolü ile ilgili yeterli veri bulunmamaktadır. Bu çalışmada, SPECT MPI’da CAR ve iskemi varlığı arasındaki ilişkiyi araştırmayı amaçladık. Yöntem: Ekim 2017 ve Haziran 2019 tarihleri arasında kardiyoloji polikliniğinden yönlendirilerek SPECT MPI yapılan 2,048 hasta retrospektif olarak değerlendirildi. Tarama popülasyonu değerlendirildiğinde serum CRP ve albümin düzeyleri ölçülen ve dışlama ölçütlerini karşılamayan 126 hasta çalışma grubunu oluşturdu. SPECT MPI’da iskemi varlığı ve yokluğuna göre hastalar iki gruba ayrılarak veriler değerlendirildi. Bulgular: Laboratuvar bulguları açısından değerlendirildiğinde iskemi bulunan grupta CRP ve CAR anlamlı olarak daha yüksek iken, bu grupta serum albümini anlamlı olarak daha düşük bulundu (her biri için p<0,05). Çok değişkenli analizde, iskemi varlığının bağımsız prediktörleri hipertansiyon ve CAR idi (CAR; göreceli olasılıklar oranı: 5,720,%95 CI: 2,697-12,133, p<0,001). İskemi varlığı için en uygun CAR değeri %76 hassasiyet ve %71 özgüllük ile 0,96 olarak bulunmuştur. Sonuç: Çalışmamız miyokard iskemisi ve CAR değerleri arasındaki ilişkiyi araştıran ilk çalışma olarak değerlidir. Miyokard perfüzyon sintigrafisi öncesi bakılan CAR değerleri iskemi için prediktör olarak bulundu.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | efe s, Candan O, GÜNDOĞAN C, OZ A, yuksel y, Ayca B, Cermik T (2020). Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy. , 112 - 117. 10.4274/mirt.galenos.2020.88261 |
| Chicago | efe suleyman,Candan Ozlem Ozdemir,GÜNDOĞAN Cihan,OZ AHMET,yuksel yasin,Ayca Burak,Cermik Tevfik Fikret Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy. (2020): 112 - 117. 10.4274/mirt.galenos.2020.88261 |
| MLA | efe suleyman,Candan Ozlem Ozdemir,GÜNDOĞAN Cihan,OZ AHMET,yuksel yasin,Ayca Burak,Cermik Tevfik Fikret Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy. , 2020, ss.112 - 117. 10.4274/mirt.galenos.2020.88261 |
| AMA | efe s,Candan O,GÜNDOĞAN C,OZ A,yuksel y,Ayca B,Cermik T Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy. . 2020; 112 - 117. 10.4274/mirt.galenos.2020.88261 |
| Vancouver | efe s,Candan O,GÜNDOĞAN C,OZ A,yuksel y,Ayca B,Cermik T Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy. . 2020; 112 - 117. 10.4274/mirt.galenos.2020.88261 |
| IEEE | efe s,Candan O,GÜNDOĞAN C,OZ A,yuksel y,Ayca B,Cermik T "Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy." , ss.112 - 117, 2020. 10.4274/mirt.galenos.2020.88261 |
| ISNAD | efe, suleyman vd. "Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy". (2020), 112-117. https://doi.org/10.4274/mirt.galenos.2020.88261 |
| APA | efe s, Candan O, GÜNDOĞAN C, OZ A, yuksel y, Ayca B, Cermik T (2020). Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy. Molecular Imaging and Radionuclide Therapy, 29(3), 112 - 117. 10.4274/mirt.galenos.2020.88261 |
| Chicago | efe suleyman,Candan Ozlem Ozdemir,GÜNDOĞAN Cihan,OZ AHMET,yuksel yasin,Ayca Burak,Cermik Tevfik Fikret Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy. Molecular Imaging and Radionuclide Therapy 29, no.3 (2020): 112 - 117. 10.4274/mirt.galenos.2020.88261 |
| MLA | efe suleyman,Candan Ozlem Ozdemir,GÜNDOĞAN Cihan,OZ AHMET,yuksel yasin,Ayca Burak,Cermik Tevfik Fikret Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy. Molecular Imaging and Radionuclide Therapy, vol.29, no.3, 2020, ss.112 - 117. 10.4274/mirt.galenos.2020.88261 |
| AMA | efe s,Candan O,GÜNDOĞAN C,OZ A,yuksel y,Ayca B,Cermik T Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy. Molecular Imaging and Radionuclide Therapy. 2020; 29(3): 112 - 117. 10.4274/mirt.galenos.2020.88261 |
| Vancouver | efe s,Candan O,GÜNDOĞAN C,OZ A,yuksel y,Ayca B,Cermik T Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy. Molecular Imaging and Radionuclide Therapy. 2020; 29(3): 112 - 117. 10.4274/mirt.galenos.2020.88261 |
| IEEE | efe s,Candan O,GÜNDOĞAN C,OZ A,yuksel y,Ayca B,Cermik T "Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy." Molecular Imaging and Radionuclide Therapy, 29, ss.112 - 117, 2020. 10.4274/mirt.galenos.2020.88261 |
| ISNAD | efe, suleyman vd. "Value of C-reactive Protein/Albumin Ratio for Predicting Ischemia in Myocardial Perfusion Scintigraphy". Molecular Imaging and Radionuclide Therapy 29/3 (2020), 112-117. https://doi.org/10.4274/mirt.galenos.2020.88261 |
