Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential
Yıl: 2020 Cilt: 26 Sayı: 4 Sayfa Aralığı: 297 - 302 Metin Dili: İngilizce DOI: 10.4274/tnd.2020.28003 İndeks Tarihi: 12-06-2021
Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential
Öz: Objective: To decompose a part of the nerve action potential (NAP), mainly originating from large-myelinated sensory fibers, from mixed NAPs by using a stimulus with long duration during surface recordings.Materials and Methods: Median and ulnar mixed NAPs were elicited using submaximal stimulus intensities with 0.5 and 1.0-ms stimulus duration, which were adjusted to just below the threshold to activate motor fibers as detected visually through muscle twitch in hand muscles, by stimulating the median and ulnar nerves at the wrist and elbow and recording from the median and ulnar nerves at both the elbow and axilla, respectively. Healthy controls and patients with demyelinating neuropathy and/or motor conduction block were included in the study.Results: Mixed NAPs were recorded in 24 healthy subjects and three patients who had multifocal motor neuropathy (MMN), acute motor axonal neuropathy (AMAN), and ulnar entrapment neuropathy (UEN). Reference values were calculated in the healthy subjects. In patients with AMAN and MMN, mixed NAPs were normal, whereas in UEN, ulnar mixed NAPs had prolonged latencies.Conclusion: Mixed NAPs elicited by stimuli with long duration and low strength in the upper limbs can be used to detect sensory involvement at segments where motor conduction block exists and might help to classify demyelinating neuropathies.
Anahtar Kelime: Karma Sinir İletim İncelemesinde Uyarı Süresi: Duyusal Potansiyelinin Ayrıştırılması
Öz: Amaç: Bu çalışmada, yüzeyel sinir iletim incelemesinde uzun süreli uyarı kullanılarak, mikst sinir aksiyon potansiyeli (SAP) içerisinde ağırlıklı olarak kalın myelinli duyusal liflerden köken alan SAP parçasının ayrıştırılması amaçlanmıştır. Gereç ve Yöntem: Medyan ve ulnar mikst SAP yanıtları bilekte ve dirsekte medyan ve ulnar sinir üzerine 0,5 ve 1,0 ms uyarı süresi ve submaksimal uyarı şiddeti kullanılarak kaydedildi. Submaksimal uyarı şiddeti, medyan ve ulnar sinir innervasyonlu distal el kaslarında görsel olarak kas kasılması izlenmeyen en yüksek uyarı şiddeti olarak belirlendi. Yüzeyel kayıt elektrotları sırasıyla dirsek ve aksillada medyan ve ulnar sinir trasesi üzerine yerleştirildi. Sağlıklı kontroller ve demiyelinizan nöropatili ve/veya motor ileti bloklu hastalar çalışmaya dahil edildi. Bulgular: Mikst SAP’ler 24 sağlıklı kontrol ve multifokal motor nöropati (MMN), akut motor aksonal nöropati (AMAN) ve ulnar tuzak nöropatisi (UTN) olan 3 hastada kaydedildi. Referans değerleri sağlıklı kontrollerde hesaplandı. AMAN ve MMN tanılı hastalarda mikst SAP’ler normal olarak izlenirken, UTN olan hastada uzun latanslı olarak kaydedildi. Sonuç: Düşük uyarı şiddeti ve uzun süreli uyarı ile kaydedilen mikst SAP’ler motor ileti bloğunun bulunduğu segmentlerde duyusal tutuluşu göstermek amacıyla kullanılabilir. Bu ileti incelemeleri demiyelinizan nöropatilerin sınıflandırılmasında fayda sağlayabilir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Sirin N, Kocasoy Orhan E, Alpaydın Baslo S, Soysal A, Uluc K, Baslo M (2020). Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential. , 297 - 302. 10.4274/tnd.2020.28003 |
| Chicago | Sirin Nermin Gorkem,Kocasoy Orhan Elif,Alpaydın Baslo Sezin,Soysal Aysun,Uluc Kayihan,Baslo Mehmet Baris Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential. (2020): 297 - 302. 10.4274/tnd.2020.28003 |
| MLA | Sirin Nermin Gorkem,Kocasoy Orhan Elif,Alpaydın Baslo Sezin,Soysal Aysun,Uluc Kayihan,Baslo Mehmet Baris Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential. , 2020, ss.297 - 302. 10.4274/tnd.2020.28003 |
| AMA | Sirin N,Kocasoy Orhan E,Alpaydın Baslo S,Soysal A,Uluc K,Baslo M Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential. . 2020; 297 - 302. 10.4274/tnd.2020.28003 |
| Vancouver | Sirin N,Kocasoy Orhan E,Alpaydın Baslo S,Soysal A,Uluc K,Baslo M Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential. . 2020; 297 - 302. 10.4274/tnd.2020.28003 |
| IEEE | Sirin N,Kocasoy Orhan E,Alpaydın Baslo S,Soysal A,Uluc K,Baslo M "Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential." , ss.297 - 302, 2020. 10.4274/tnd.2020.28003 |
| ISNAD | Sirin, Nermin Gorkem vd. "Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential". (2020), 297-302. https://doi.org/10.4274/tnd.2020.28003 |
| APA | Sirin N, Kocasoy Orhan E, Alpaydın Baslo S, Soysal A, Uluc K, Baslo M (2020). Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential. Türk Nöroloji Dergisi, 26(4), 297 - 302. 10.4274/tnd.2020.28003 |
| Chicago | Sirin Nermin Gorkem,Kocasoy Orhan Elif,Alpaydın Baslo Sezin,Soysal Aysun,Uluc Kayihan,Baslo Mehmet Baris Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential. Türk Nöroloji Dergisi 26, no.4 (2020): 297 - 302. 10.4274/tnd.2020.28003 |
| MLA | Sirin Nermin Gorkem,Kocasoy Orhan Elif,Alpaydın Baslo Sezin,Soysal Aysun,Uluc Kayihan,Baslo Mehmet Baris Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential. Türk Nöroloji Dergisi, vol.26, no.4, 2020, ss.297 - 302. 10.4274/tnd.2020.28003 |
| AMA | Sirin N,Kocasoy Orhan E,Alpaydın Baslo S,Soysal A,Uluc K,Baslo M Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential. Türk Nöroloji Dergisi. 2020; 26(4): 297 - 302. 10.4274/tnd.2020.28003 |
| Vancouver | Sirin N,Kocasoy Orhan E,Alpaydın Baslo S,Soysal A,Uluc K,Baslo M Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential. Türk Nöroloji Dergisi. 2020; 26(4): 297 - 302. 10.4274/tnd.2020.28003 |
| IEEE | Sirin N,Kocasoy Orhan E,Alpaydın Baslo S,Soysal A,Uluc K,Baslo M "Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential." Türk Nöroloji Dergisi, 26, ss.297 - 302, 2020. 10.4274/tnd.2020.28003 |
| ISNAD | Sirin, Nermin Gorkem vd. "Stimulus Duration in a Mixed Nerve Conduction Study: Decomposing Sensory Potential". Türk Nöroloji Dergisi 26/4 (2020), 297-302. https://doi.org/10.4274/tnd.2020.28003 |
