The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum
Yıl: 2020 Cilt: 7 Sayı: 3 Sayfa Aralığı: 124 - 127 Metin Dili: İngilizce DOI: 10.47572/muskutd.677093 İndeks Tarihi: 15-06-2021
The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum
Öz: This study was aimed to investigate the diagnostic value of theneutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio(PLR), platelet distribution width (PDW), mean platelet volume(MPV), plateletcrit (PCT) and red cell distribution width (RDW)in patients with hyperemesis gravidarum (HG). We conducted thisretrospective study in a tertiary center between August andDecember 2019.A total of 72 pregnant patients with HG and 78pregnant women without nausea and vomiting were included in thestudy. Hemoglobin (Hb), white blood cell count (WBC), neutrophilcount, lymphocyte count, platelet count, RDW, PDW, MPV, PCT,and CRP values were all derived from patients' medical files. Thestudent's t-test was used to compare the normally distributed data.Mann-Whitney U test was used to compare the non-normallydistributed data. The median NLR value of the HG group was 3.4(1.1-7.2), and the control group was 1.98 (1.0-4.6). This differencewas statistically significant (p<0.05). The median PLR value of theHG group (152.6 [69.8-338.1]) was significantly higher (p<0.05)than the PLR value of the control group (88.1 [48.3-201.2]). Theresults of this study suggest that NLR and PLR can be used aseffective markers in the diagnosis of HG. The increased values ofNLR and PLR also indicate that inflammation may act a crucialrole in the pathogenesis of HG.
Anahtar Kelime: Sistemik İnflamatuar Belirteçlerin Hyperemezis Gravidarum Tanısındaki Rolü
Öz: Bu çalışmada hiperemezis gravidarumu olan hastalarda nötrofillenfosit oranı (NLO), trombosit-lenfosit oranı (TLO), trombosit dağılım genişliği (TDG), ortalama trombosit hacmi (OTH), plateletcrit (PKT) ve eritrosit dağılım genişliğinin (EDG) tanısal değeri araştırılmıştır. Bu retrospektif çalışmayı üçüncü basamak bir merkezde Ağustos ve Aralık 2019 tarihleri arasında gerçekleştirdik. Çalışmaya hiperemezis gravidarumu olan 72 hasta ve bulantı ve kusması olmayan 78 gebe dahil edildi. Hemoglobin (Hb), EDG, TDG, OTH, PKT ve C-reaktif protein (CRP) değerleri hastaların tıbbi dosyalarından elde edildi. Normal dağılım gösteren verileri karşılaştırmak için Student's t testi, normal dağılıma uymayan verileri karşılaştırmak için Mann-Whitney U testi kullanıldı. HG grubunun ortanca NLO değeri 3.4 (1.1-7.2), kontrol grubunun 1.98 (1.0-4.6) idi. Bu farklılık istatistiksel olarak anlamlıydı (p<0.05). HG grubunun ortanca PLO değeri (152.6 [69.8-338.1]), kontrol grubunun PLO değerinden (88.1 [48.3- 201.2]) anlamlı olarak daha yüksekti (p<0.05). Bu çalışmanın sonuçları NLO ve PLO’nun HG tanısında etkili belirteçler olarak kullanılabileceğini düşündürmektedir. Artan NLO ve PLO değerleri, inflamasyonun HG patogenezinde önemli bir rol oynuyor olabileceğini de göstermektedir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Oglak S, obut m (2020). The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum. , 124 - 127. 10.47572/muskutd.677093 |
| Chicago | Oglak Süleyman Cemil,obut mehmet The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum. (2020): 124 - 127. 10.47572/muskutd.677093 |
| MLA | Oglak Süleyman Cemil,obut mehmet The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum. , 2020, ss.124 - 127. 10.47572/muskutd.677093 |
| AMA | Oglak S,obut m The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum. . 2020; 124 - 127. 10.47572/muskutd.677093 |
| Vancouver | Oglak S,obut m The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum. . 2020; 124 - 127. 10.47572/muskutd.677093 |
| IEEE | Oglak S,obut m "The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum." , ss.124 - 127, 2020. 10.47572/muskutd.677093 |
| ISNAD | Oglak, Süleyman Cemil - obut, mehmet. "The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum". (2020), 124-127. https://doi.org/10.47572/muskutd.677093 |
| APA | Oglak S, obut m (2020). The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, 7(3), 124 - 127. 10.47572/muskutd.677093 |
| Chicago | Oglak Süleyman Cemil,obut mehmet The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 7, no.3 (2020): 124 - 127. 10.47572/muskutd.677093 |
| MLA | Oglak Süleyman Cemil,obut mehmet The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, vol.7, no.3, 2020, ss.124 - 127. 10.47572/muskutd.677093 |
| AMA | Oglak S,obut m The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi. 2020; 7(3): 124 - 127. 10.47572/muskutd.677093 |
| Vancouver | Oglak S,obut m The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi. 2020; 7(3): 124 - 127. 10.47572/muskutd.677093 |
| IEEE | Oglak S,obut m "The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum." Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, 7, ss.124 - 127, 2020. 10.47572/muskutd.677093 |
| ISNAD | Oglak, Süleyman Cemil - obut, mehmet. "The Role of Systemic Inflammatory Markers in the Diagnosis of Hyperemesis Gravidarum". Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 7/3 (2020), 124-127. https://doi.org/10.47572/muskutd.677093 |
