Introduction: Suicide attempts by overdose drug intake areimportant public health problems in adolescents. The aim of thisstudy was to evaluate the demographic and clinical characteristics ofthe patients with suicide attempts. Methods: Adolescents, who were admitted to our pediatricemergency department with suicide attempt between January 1,2014 and December 31, 2018, were evaluated retrospectively. Results: The median age of 784 patients included in the studywas 190 months and 662 (84.4%) of them were female. It wasdetermined that 429 (54.7%) of the cases were taking multipledrugs. Analgesic drug intake (non-steroidal anti-inflammatory andparacetamol) was the most common (47.1%), antidepressant(22.6%) and common cold drugs (18.0%) were second and thirdrespectively. One hundred-three (13.1%) of the cases were in earlyadolescence (9-13 years), 533 (68.0%) were in middle adolescence(14-16 years), 148 of them were in late adolescence (17-19 years).Of our patients, 201 (25.6%) had pediatric psychiatry follow-up and154 (19.6%) were taking regular medication. It was determined that185 (23.6%) of the cases had two or more suicides attempts. Themost common symptoms were detected as gastrointestinal (60.3%)and neurological (42.6%) symptoms. Seven hundred-forty two(94.6%) of the cases were hospitalized [380 (51.2%) in emergencyobservation, 188 (25.3%) in intensive care unit, 174 (23.5%)in pediatric ward]. It was found that 3 (0.4%) patients who diedwere female and it was their first suicide attempts and they weretaking single drug (amphetamine, antidepressant and angiotensin-IIantagonist). Conclusion: Suicidal drug intoxications are more common in middleadolescence and girls. Multiple drugs and especially accessible non prescription drugs are poisoning agents. Multidisciplinary follow-upis important for the risk of recurrence of suicide attempts.