Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?

Yıl: 2021 Cilt: 22 Sayı: 1 Sayfa Aralığı: 13 - 18 Metin Dili: İngilizce DOI: 10.4274/imj.galenos.2020.57767 İndeks Tarihi: 29-07-2022

Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?

Öz:
Introduction: On admission to the intensive care unit (ICU), functional and general health stata are important baseline characteristics of critically ill patients with chronic obstructivepulmonary disease (COPD). The measurement of total psoas muscle area (PMA) is under investigation to determine physical frailty and sarcopenia, especially encountered in the elderly, to predict adverse outcomes and mortality in patients requiring inhospital and ICU management. We aimed to assess the clinical value of total PMA for the prediction of mortality in COPD patients requiring ICU management of acute exacerbations. Methods: The clinical data of 62 patients whose abdominal computed tomography (CT) scans were available in the hospital Picture Archiving Communication System were collected. Themean duration of stay in the ICU was 7.7±8.8 and 9.4±12.3 days in survivors and non-survivors. The main causes of mortality in non-survivors were respiratory failure and cardiac arrest. For measurements from CT scans, images of the caudal end of the third lumbar vertebra were used. Right and left PMAs were measured to obtain the total PMA and density. Results: Of 62 patients, 20 (32.2%) were non-survivors (male: 13, female: 7), and 42 were survivors (male: 32, female: 10). There was no significant difference between non-survivors and survivors regarding total PMA and density values (p>0.05). In non-survivors and survivors, females had lower total PMA (p<0.05). There was no significant association between clinical and PMA data (p>0.05).
Anahtar Kelime:

Yoğun Bakım Ünitesinde Tedavi Edilen Kronik Obstrüktif Akciğer Hastalarında Sarkopeni Mortalite ile İlişkili midir?

Öz:
Amaç: Yoğun bakım ünitesine (YBÜ) kabul aşamasında, ileri derecede kronik obstrüktif akciğer hastalığı (KOAH) olan hastaların fonksiyonel ve genel sağlık durumları önem arz eder. Toplam psoas kas alanının (PKA) ölçümü, hastane ve YBÜ tedavisi gerektiren, özellikle yaşlı hastalarda, olumsuz sonuçları ve mortaliteyi tahmin etmek için, fiziksel kırılganlık ve sarkopeninin araştırılmasında kullanılan bir yöntemdir. Bu çalışmada, KOAH akut alevlenme nedeniyle YBÜ tedavisi gereken hastalarda, mortalitenin tahmini için total PKA’nın klinik değerini araştırmayı amaçladık. Yöntemler: Bu kesitsel çalışmaya akut KOAH atağı ile YBÜ’de tedavi edilen hastalar alındı. Abdominal bilgisayarlı tomografisi (BT) olan 62 hastanın verileri toplandı. Yoğun bakımda kalış süresi yaşayan hastalar ve ölenlerde ortalama 7,7±8,8 ve 9,4±12,3 gün idi. Mortalite gelişen hastlarda en sık sebepler solunum yetmezliği ve kardiyak arrestti. BT ölçümlerinde 3. lumbal vertebranın kadual ucunun görüntüsü kullanıldı. Total PKA’nın hesaplanması için, sağ ve sol PKA dansite değerleri ile birlikte ölçüldü. Bulgular: Çalışmaya dahil edilen 62 hastanın 20’si ölmüşken (erkek: 13, kadın: 7), 42’si sağ kalmıştır (erkek: 32, kadın: 10). Ölenler ile yaşayanlar arasında total PKA ve dansite değerleri açısından anlamlı bir fark bulunmadı (p>0,05). Kadın hastaların total PKA değeri ölenlerde yaşayanlara göre anlamlı derecede düşük bulunmuştur (p<0,05). Hastaların klinik verileri ile PKA değeri arasında anlamlı bir ilişki bulunmadı (p>0,05).
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA toptaş m, Yurt S, haliloglu m, Tuna L, KARAPINAR K, AKKOÇ İ, Kirkil G, Çınarka H (2021). Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?. , 13 - 18. 10.4274/imj.galenos.2020.57767
Chicago toptaş mehmet,Yurt Sibel,haliloglu murat,Tuna Lale,KARAPINAR KEMAL,AKKOÇ İbrahim,Kirkil Gamze,Çınarka Halit Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?. (2021): 13 - 18. 10.4274/imj.galenos.2020.57767
MLA toptaş mehmet,Yurt Sibel,haliloglu murat,Tuna Lale,KARAPINAR KEMAL,AKKOÇ İbrahim,Kirkil Gamze,Çınarka Halit Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?. , 2021, ss.13 - 18. 10.4274/imj.galenos.2020.57767
AMA toptaş m,Yurt S,haliloglu m,Tuna L,KARAPINAR K,AKKOÇ İ,Kirkil G,Çınarka H Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?. . 2021; 13 - 18. 10.4274/imj.galenos.2020.57767
Vancouver toptaş m,Yurt S,haliloglu m,Tuna L,KARAPINAR K,AKKOÇ İ,Kirkil G,Çınarka H Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?. . 2021; 13 - 18. 10.4274/imj.galenos.2020.57767
IEEE toptaş m,Yurt S,haliloglu m,Tuna L,KARAPINAR K,AKKOÇ İ,Kirkil G,Çınarka H "Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?." , ss.13 - 18, 2021. 10.4274/imj.galenos.2020.57767
ISNAD toptaş, mehmet vd. "Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?". (2021), 13-18. https://doi.org/10.4274/imj.galenos.2020.57767
APA toptaş m, Yurt S, haliloglu m, Tuna L, KARAPINAR K, AKKOÇ İ, Kirkil G, Çınarka H (2021). Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?. İstanbul Medical Journal, 22(1), 13 - 18. 10.4274/imj.galenos.2020.57767
Chicago toptaş mehmet,Yurt Sibel,haliloglu murat,Tuna Lale,KARAPINAR KEMAL,AKKOÇ İbrahim,Kirkil Gamze,Çınarka Halit Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?. İstanbul Medical Journal 22, no.1 (2021): 13 - 18. 10.4274/imj.galenos.2020.57767
MLA toptaş mehmet,Yurt Sibel,haliloglu murat,Tuna Lale,KARAPINAR KEMAL,AKKOÇ İbrahim,Kirkil Gamze,Çınarka Halit Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?. İstanbul Medical Journal, vol.22, no.1, 2021, ss.13 - 18. 10.4274/imj.galenos.2020.57767
AMA toptaş m,Yurt S,haliloglu m,Tuna L,KARAPINAR K,AKKOÇ İ,Kirkil G,Çınarka H Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?. İstanbul Medical Journal. 2021; 22(1): 13 - 18. 10.4274/imj.galenos.2020.57767
Vancouver toptaş m,Yurt S,haliloglu m,Tuna L,KARAPINAR K,AKKOÇ İ,Kirkil G,Çınarka H Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?. İstanbul Medical Journal. 2021; 22(1): 13 - 18. 10.4274/imj.galenos.2020.57767
IEEE toptaş m,Yurt S,haliloglu m,Tuna L,KARAPINAR K,AKKOÇ İ,Kirkil G,Çınarka H "Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?." İstanbul Medical Journal, 22, ss.13 - 18, 2021. 10.4274/imj.galenos.2020.57767
ISNAD toptaş, mehmet vd. "Is Sarcopenia Related to Mortality in Patients with Chronic Obstructive Pulmonary Disease in the Intensive Care Unit?". İstanbul Medical Journal 22/1 (2021), 13-18. https://doi.org/10.4274/imj.galenos.2020.57767