İlknur KÜLHAŞ ÇELİK
(Sağlık Bilimleri Üniversitesi, Ankara Çocuk Sağlığı ve Hastalıkları Hematoloji Onkoloji Eğitim ve Araştırma Hastanesi, Anabilim Dalı Pediatrik Alerji ve İmmünoloji, Ankara, Türkiye)
ERSOY CİVELEK
(Sağlık Bilimleri Üniversitesi, Ankara Çocuk Sağlığı ve Hastalıkları Hematoloji Onkoloji Eğitim ve Araştırma Hastanesi, Anabilim Dalı Pediatrik Alerji ve İmmünoloji, Ankara, Türkiye)
Ayşe Betül BÜYÜKTİRYAKİ
(Sağlık Bilimleri Üniversitesi, Ankara Çocuk Sağlığı ve Hastalıkları Hematoloji Onkoloji Eğitim ve Araştırma Hastanesi, Anabilim Dalı Pediatrik Alerji ve İmmünoloji, Ankara, Türkiye)
Emine Sena ALABOYUN
(Sağlık Bilimleri Üniversitesi, Ankara Çocuk Sağlığı ve Hastalıkları Hematoloji Onkoloji Eğitim ve Araştırma Hastanesi, Anabilim Dalı Pediatri, Ankara, Türkiye)
Tayfur GİNİŞ
(Sağlık Bilimleri Üniversitesi, Ankara Çocuk Sağlığı ve Hastalıkları Hematoloji Onkoloji Eğitim ve Araştırma Hastanesi, Anabilim Dalı Pediatrik Alerji ve İmmünoloji, Ankara, Türkiye)
Emine DİBEK MISIRLIOĞLU
(Sağlık Bilimleri Üniversitesi, Ankara Çocuk Sağlığı ve Hastalıkları Hematoloji Onkoloji Eğitim ve Araştırma Hastanesi, Anabilim Dalı Pediatrik Alerji ve İmmünoloji, Ankara, Türkiye)
Müge TOYRAN
(Sağlık Bilimleri Üniversitesi, Ankara Çocuk Sağlığı ve Hastalıkları Hematoloji Onkoloji Eğitim ve Araştırma Hastanesi, Anabilim Dalı Pediatrik Alerji ve İmmünoloji, Ankara, Türkiye)
Can Naci KOCABAŞ
(Muğla Sıtkı Koçman Üniversitesi, Tıp Fakültesi, Çocuk Alerji ve İmmünoloji Anabilim Dalı Çocuk Sağlığı ve Hastalıkları Anabilim Dalı Muğla, Türkiye)
Yıl: 2020Cilt: 14Sayı: 5ISSN: 1307-4490 / 2148-3566Sayfa Aralığı: 396 - 401İngilizce

56 0
Food Sensitization Patterns of Infants with Food-Triggered Atopic Dermatitis
Objective: Food allergen sensitization patterns vary among patients with atopic dermatitis in different countries. Theaim of this study was to determine the food sensitization patterns of infants with food-triggered atopic dermatitis.Material and Methods: The study was a retrospective evaluation of atopic dermatitis patients who were followed atthe Pediatric Allergy and Immunology Clinic of our hospital. Among these patients, those who had both positive skinprick test and positive serum specific IgE to a food were included in the study. The diagnosis of food sensitization wasconfirmed upon improvement with an elimination dietResults: A total of 204(74.5% boys) atopic dermatitis patients less than 1 year of age were found to have food-trigerredatopic dermatitis. Median age at diagnosis was 3 months(interquartile range: 1-5.8). When skin prick test and serumspecific IgE results were analyzed, we found sensitivity to egg in 85.8%, milk in 35.5%, wheat in 3.9%, walnut in 1.5%,peanut in 2.5%, and fish in 2% of the patients. None of the patients showed sensitivity to soybean.Conclusion: Our findings indicated that a large portion of our patients were male, egg was the most common foodsensitivity, the prevalence of peanut sensitivity was less than other countries and none of the patients had soy sensitivity
DergiAraştırma MakalesiErişime Açık
  • 1. Eichenfield LF, Ahluwalia J, Waldman A, Borok J, Jeremy Udkoff J, Boguniewicz M. Current guidelines for the evaluation and management of atopic dermatitis: A comparison of the Joint Task Force Practice Parameter and American Academy of Dermatology guidelines. J Allergy Clin Immunol 2017;139:49-S57.
  • 2. Beasley R. The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee. Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. Lancet 1998;351:1225-32.
  • 3. Roduit C, Frei R, Loss G, Buchele G, Weber J, Depner M, et al. Development of atopic dermatitis according to age of onset and association with early-life exposures. J Allergy Clin Immunol 2012;130:130-136.e5.
  • 4. Shaw TE, Currie GP, Koudelka CW, Simpson EL. Eczema prevalence in the United States: data from the 2003 National Survey of Children’s Health. J Invest Dermatol 2011;131:67-73.
  • 5. Kay J, Gawkrodger DJ, Mortimer MJ, Jaron AG. The prevalence of childhood atopic eczema in a general population. J Am Acad Dermatol 1994;30:35-9.
  • 6. Palmer CN, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP, et al. Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet 2006;38:441-6.
  • 7. Eigenmann P, Sicherer S, Borkowski T, Cohen B, Sampson H. Prevalence of IgE-mediated food allergy among children with atopic dermatitis. Pediatrics 1998;101:E8.
  • 8. Eigenmann PC, Calza AM. Diagnosis of IgE-mediated food allergy among Swiss children with atopic dermatitis. Pediatric Allergy Immunol 2000;11:95-100.
  • 9. Burks AW, James JM, Hiegel A, Wilson G, Wheeler JG, Jones SM, et al. Atopic dermatitis and food hypersensitivity reactions. J Pediatr 1998:132-6.
  • 10. Forbes LR, Saltzman RW, Spergel JM. Food allergies and atopic dermatitis: differentiating myth from reality. Pediatr Ann 2009;38:84- 90.
  • 11. Bergmann MM, Caubet JC, Boguniewicz M, Eigenmann PA . Evaluation of food allergy in patients with atopic dermatitis. J Allergy Clin Immunol Pract 2013;1:22-8.
  • 12. de Benedictis FM, Franceschini F, Hill D, Naspitz C, Simons FE, Wahn U, Warner JO, de Longueville M; EPAAC Study Group. The allergic sensitization in infants with atopic eczema from di erent countries. Allergy 2009;64:295-303.
  • 13. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Dermato-Venereologica 1980; 92:44-7.
  • 14. Atherton DJ, Sweel M, Soothill JF, Wells RS, Chilvers CE. A double-blind controlled crossover trial of an antigen-avoidance diet in atopic eczema. Lancet 1978;1:401-3.
  • 15. Bergmann MM, Caubet JC, Boguniewicz M, Eigenmann PA. Evaluation of food allergy in patients with atopic dermatitis. J Allergy Clin Immunol Pract 2013;1:22-8.
  • 16. du Toit G, Roberts G, Sayre PH, Bahnson HT, Radulovic S, Santos AF, et al. Randomized trial of peanut consumption in infants at risk for peanut allergy. N Engl J Med 2015;372:803-
  • 17. Perkin MR, Logan K, Tseng A, Raji B, Ayis S, Peacock J, et al. Randomized trial of introduction of allergenic foods in breastfed infants. N Engl J Med 2016;374:1733-43.
  • 18. Sisherer SH, Sampson HA. Food Hypersensitivity and atopic dermatitis: pathophysiology, epidemiology, diagnosis, and management. J Allergy Clin Immunol 1999 ;104:114-22.
  • 19. Chang A, Robison RA, Cai M, Singh AM. Natural History of Children with Food Triggered Atopic Dermatitis and Development of Immediate Reactions. J Allergy Clin Immunol 2015;2: 229-36.
  • 20. Knox SM, Erwin EA, Joy L. Mosser-Goldfarb, Rebecca Scherzer. Sensitization patterns among patients with atopic dermatitis evaluated in a large tertiary care pediatric center. Ann Allergy Asthma Immunol 2017; 629-47.
  • 21. Mahdavinia M, Rasmussen HE, Engen P, Van den Berg JP, Davis E, Engen K, et al. Ann Allergy Asthma Immunol 2017;118:742-3.
  • 22. Emeksiz ZS, Cavkaytar O, Aksoy I, Dallar Y, Soyer O. Food Hypersensitivity in Atopic Dermatitis During Infancy: skin Prick Testing for Whom? Asthma Allergy Immunol 2017;15:32-7.
  • 23. Lack G, Fox D, Northstone K, Golding J. Factors associated with the development of peanut allergy in childhood. N Engl J Med 2003;348:977-85.
  • 24. Fox AT, Sasieni P, du Toit G, Syed H, Lack G. Household peanut consumption as a risk factor for the development of peanut allergy. J Allergy Clin Immunol 2009;123:417-23.

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