Objective: This study aimed to investigate the presence of neuropathic pain (NP) in female patients after total knee arthroplasty (TKA) alongwith NP-associated factors.Materials and Methods: In total, 85 female patients who underwent TKA due to knee osteoarthritis were included in this study. Sociodemographic factors along with medical and psychological comorbidities were investigated. Pain levels were assessed using the visualanalogue scale (VAS) and Western Ontario and McMaster Universities Arthritis Index (WOMAC) pain scales. The functional status wasassessed using the WOMAC physical function scales. Importantly, the presence of NP was assessed using the PainDETECT questionnaire. Theemotional status of the patients was assessed using the hospital anxiety depression scale.Results: In total, 9 (10.6%) patients were classified as having likely NP and 14 (16.5%) as having possible NP. The PainDETECT scoreswere significantly correlated with the preoperative VAS scores (p=0.004), WOMAC pain (p=0.000) and physical function scores (p=0.007)and presence of depression (p=0.021) Furthermore, the PainDETECT scores were significantly negatively correlated with the period afterarthroplasty (p=0.033). No correlation was found between NP and socio-demographic factors and medical comorbidities.Conclusion: Patients with NP had a shorter period after arthroplasty, depression, an increased severity of pain and a decreased physicalfunction. The presence of NP in the patients who underwent TKA should be considered and associated factors should be evaluated.