Yıl: 2021 Cilt: 22 Sayı: 3 Sayfa Aralığı: 247 - 250 Metin Dili: İngilizce DOI: 10.5152/TurkThoracJ.2021.20284 İndeks Tarihi: 01-10-2021

Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study

Öz:
To evaluate the clinical features and outcomes of patients who were admitted with a diagnosis of coronavirus disease 2019(COVID-19) but who were not confirmed with polymerase chain reaction (PCR) positivity.MATERIAL AND METHODS: This is a retrospective analysis of all patients admitted to two tertiary care centers between March 15 andMay 15, 2020, with a diagnosis of COVID-19. From a common database prepared for COVID-19, we retrieved the relevant data andcompared the clinical findings and outcomes of PCR-positive patients with those of PCR-negative cases who had been diagnosed on thebasis of typical clinical and radiographic findings.RESULTS: A total of 349 patients were included in the analysis, of which 126 (36.1%) were PCR-negative. PCR-negative patients wereyounger (54.6 ± 20.8 vs. 60.8 ± 18.9 years, P = .009) but were similar to PCR-positive patients in terms of demographics, comorbidities,and presenting symptoms. They had higher lymphocyte counts (1519 ± 868 vs. 1331 ± 737/mm3, P = .02) and less frequently presentedwith bilateral radiographic findings (68.3% vs. 79.4%, P = .046) than PCR-positive patients. Besides, they had less severe disease andbetter clinical outcomes regarding admission to the intensive care unit (9.6% vs. 20.6%, P = .023), oxygen therapy (21.4% vs. 43.5%, P< .001), ventilatory support (3.2% vs. 11.2%, P = .03) and length of hospital stay (5.0 ± 5.0 vs. 9.7 ± 5.9 days, P < .001).CONCLUSION: This study confirms that about one-third of the COVID-19 patients are PCR-negative and diagnosed based on clinicaland radiographic findings. These patients have a more favorable clinical course, shorter hospital stays, and are less frequently admittedto the intensive care unit.
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Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA Sayiner A, Tasbakan M, ergan b, KILINC O, SAYINER A, Sertöz R, OZUYGUR S, ERCAN S, SAVRAN Y, Korkmaz P, Basoglu O, Ozhan M (2021). Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study. , 247 - 250. 10.5152/TurkThoracJ.2021.20284
Chicago Sayiner Abdullah,Tasbakan Mehmet Sezai,ergan begum,KILINC OGUZ,SAYINER AYCA ARZU,Sertöz Rüçhan,OZUYGUR Selin,ERCAN SELİN,SAVRAN YUSUF,Korkmaz Pervin,Basoglu Ozen K,Ozhan Mustafa Hikmet Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study. (2021): 247 - 250. 10.5152/TurkThoracJ.2021.20284
MLA Sayiner Abdullah,Tasbakan Mehmet Sezai,ergan begum,KILINC OGUZ,SAYINER AYCA ARZU,Sertöz Rüçhan,OZUYGUR Selin,ERCAN SELİN,SAVRAN YUSUF,Korkmaz Pervin,Basoglu Ozen K,Ozhan Mustafa Hikmet Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study. , 2021, ss.247 - 250. 10.5152/TurkThoracJ.2021.20284
AMA Sayiner A,Tasbakan M,ergan b,KILINC O,SAYINER A,Sertöz R,OZUYGUR S,ERCAN S,SAVRAN Y,Korkmaz P,Basoglu O,Ozhan M Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study. . 2021; 247 - 250. 10.5152/TurkThoracJ.2021.20284
Vancouver Sayiner A,Tasbakan M,ergan b,KILINC O,SAYINER A,Sertöz R,OZUYGUR S,ERCAN S,SAVRAN Y,Korkmaz P,Basoglu O,Ozhan M Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study. . 2021; 247 - 250. 10.5152/TurkThoracJ.2021.20284
IEEE Sayiner A,Tasbakan M,ergan b,KILINC O,SAYINER A,Sertöz R,OZUYGUR S,ERCAN S,SAVRAN Y,Korkmaz P,Basoglu O,Ozhan M "Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study." , ss.247 - 250, 2021. 10.5152/TurkThoracJ.2021.20284
ISNAD Sayiner, Abdullah vd. "Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study". (2021), 247-250. https://doi.org/10.5152/TurkThoracJ.2021.20284
APA Sayiner A, Tasbakan M, ergan b, KILINC O, SAYINER A, Sertöz R, OZUYGUR S, ERCAN S, SAVRAN Y, Korkmaz P, Basoglu O, Ozhan M (2021). Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study. Turkish Thoracic Journal, 22(3), 247 - 250. 10.5152/TurkThoracJ.2021.20284
Chicago Sayiner Abdullah,Tasbakan Mehmet Sezai,ergan begum,KILINC OGUZ,SAYINER AYCA ARZU,Sertöz Rüçhan,OZUYGUR Selin,ERCAN SELİN,SAVRAN YUSUF,Korkmaz Pervin,Basoglu Ozen K,Ozhan Mustafa Hikmet Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study. Turkish Thoracic Journal 22, no.3 (2021): 247 - 250. 10.5152/TurkThoracJ.2021.20284
MLA Sayiner Abdullah,Tasbakan Mehmet Sezai,ergan begum,KILINC OGUZ,SAYINER AYCA ARZU,Sertöz Rüçhan,OZUYGUR Selin,ERCAN SELİN,SAVRAN YUSUF,Korkmaz Pervin,Basoglu Ozen K,Ozhan Mustafa Hikmet Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study. Turkish Thoracic Journal, vol.22, no.3, 2021, ss.247 - 250. 10.5152/TurkThoracJ.2021.20284
AMA Sayiner A,Tasbakan M,ergan b,KILINC O,SAYINER A,Sertöz R,OZUYGUR S,ERCAN S,SAVRAN Y,Korkmaz P,Basoglu O,Ozhan M Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study. Turkish Thoracic Journal. 2021; 22(3): 247 - 250. 10.5152/TurkThoracJ.2021.20284
Vancouver Sayiner A,Tasbakan M,ergan b,KILINC O,SAYINER A,Sertöz R,OZUYGUR S,ERCAN S,SAVRAN Y,Korkmaz P,Basoglu O,Ozhan M Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study. Turkish Thoracic Journal. 2021; 22(3): 247 - 250. 10.5152/TurkThoracJ.2021.20284
IEEE Sayiner A,Tasbakan M,ergan b,KILINC O,SAYINER A,Sertöz R,OZUYGUR S,ERCAN S,SAVRAN Y,Korkmaz P,Basoglu O,Ozhan M "Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study." Turkish Thoracic Journal, 22, ss.247 - 250, 2021. 10.5152/TurkThoracJ.2021.20284
ISNAD Sayiner, Abdullah vd. "Clinical Outcome of PCR-Negative COVID-19 Patients: A Retrospective Study". Turkish Thoracic Journal 22/3 (2021), 247-250. https://doi.org/10.5152/TurkThoracJ.2021.20284