Yıl: 2021 Cilt: 8 Sayı: 2 Sayfa Aralığı: 297 - 304 Metin Dili: Türkçe DOI: 10.34087/cbusbed. 819759 İndeks Tarihi: 02-10-2021

İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki

Öz:
Giriş ve Amaç: Çalışmada iskemik inme hastalarında hemorajik transformasyon (HT) gelişimi ile kan lipidparametrelerinin ilişkisinin incelenmesi amaçlanmıştır.Gereç ve Yöntemler: Çalışma için 2015-2020 yılları arasında nöroloji kliniğinde yatarak tedavi alan akut iskemikinme hastaları retrospektif olarak değerlendirildi. Hastalar iskemik dokuda hemorajik transformasyon olan ve olmayanhastalar olarak 2 gruba ayrıldı. Hastaların lipid profili (trigliserid, total kolesterol, LDL kolesterol ve HDL kolesterol)12 saat açlık sonrası, saat 5:00-07:00 arası alınan kan örnekleri ile değerlendirildi.Bulgular: Çalışmada iskemik dokuda HT gelişen (40) ve HT gelişmeyen (60) 100 hasta dahil edildi. Gruplar arasındaDM (p: 0.229) ve hipertansiyon (p: 0.698) açısından farklılık yoktu. Gruplar arasında trigliserit (p: 0.266) ve HDL (p:0.718) açısından anlamlı fark yokken, HT gelişen hasta gurubunda total kolesterol (p: 0.017) ve LDL kolesterol (p:0.015) seviyeleri gelişmeyen hasta gurubuna göre yüksekti ve aradaki fark anlamlıydı.Sonuç: Çalışmamızda kan lipid parametreleri ve prognoz arasında bir ilişki gözlenmedi. Fakat hemorajiktransformasyon gelişen inme hastalarında LDL kolesterol ve total kolesterol düzeylerinin hemorajik transformasyongelişmeyen iskemik inme hastalarına göre anlamlı yüksek olduğunu bulduk. Ancak bunun klinik olarak önemli biretkiye yol açıp açmadığını belirlemek için bulgularımızın, örneklem büyüklüğünün genişletilerek doğrulanmasıgerekmektedir.
Anahtar Kelime:

The Relationship Between Blood Lipid Parameters and Development of Intracerebral Hemorrhage in Ischemic Stroke Patients

Öz:
Objective: The aim of this study was to investigate the relationship between the development of hemorrhagic transformation (HT) and blood lipid parameters in patients with ischemic stroke. Materials and Methods: For the study, patients with acute ischemic stroke who received inpatient treatment in the neurology clinic between 2015-2020 were evaluated retrospectively. The patients were divided into 2 groups as patients with and without hemorrhagic transformation in ischemic tissue. The lipid profile of the patients (triglyceride, total cholesterol, LDL cholesterol and HDL cholesterol) was evaluated with blood samples taken between 5:00 and 7:00 hours after 12 hours of fasting. Results: In the study, 100 patients who developed HT in ischemic tissue (40) and did not develop HT (60) were included. There was no difference between the groups in terms of DM (p: 0.229) and hypertension (p: 0.698). While there was no significant difference between the groups in terms of triglycerides (p: 0.266) and HDL (p: 0.718), the levels of total cholesterol (p: 0.017) and LDL cholesterol (p: 0.015) were higher in the patient group who developed HT compared to the non-developed patient group, and the difference was significant. Conclusion In our study, no relationship was observed between blood lipid parameters and prognosis. However, we found that LDL cholesterol and total cholesterol levels were significantly higher in stroke patients with hemorrhagic298 transformation compared to ischemic stroke patients without hemorrhagic transformation. However, to determine whether this has had a clinically significant effect, our findings need to be confirmed by expanding the sample size.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA yücel k, EREN F (2021). İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki. , 297 - 304. 10.34087/cbusbed. 819759
Chicago yücel kamile,EREN Fettah İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki. (2021): 297 - 304. 10.34087/cbusbed. 819759
MLA yücel kamile,EREN Fettah İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki. , 2021, ss.297 - 304. 10.34087/cbusbed. 819759
AMA yücel k,EREN F İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki. . 2021; 297 - 304. 10.34087/cbusbed. 819759
Vancouver yücel k,EREN F İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki. . 2021; 297 - 304. 10.34087/cbusbed. 819759
IEEE yücel k,EREN F "İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki." , ss.297 - 304, 2021. 10.34087/cbusbed. 819759
ISNAD yücel, kamile - EREN, Fettah. "İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki". (2021), 297-304. https://doi.org/10.34087/cbusbed. 819759
APA yücel k, EREN F (2021). İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 8(2), 297 - 304. 10.34087/cbusbed. 819759
Chicago yücel kamile,EREN Fettah İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 8, no.2 (2021): 297 - 304. 10.34087/cbusbed. 819759
MLA yücel kamile,EREN Fettah İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, vol.8, no.2, 2021, ss.297 - 304. 10.34087/cbusbed. 819759
AMA yücel k,EREN F İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. 2021; 8(2): 297 - 304. 10.34087/cbusbed. 819759
Vancouver yücel k,EREN F İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. 2021; 8(2): 297 - 304. 10.34087/cbusbed. 819759
IEEE yücel k,EREN F "İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki." Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 8, ss.297 - 304, 2021. 10.34087/cbusbed. 819759
ISNAD yücel, kamile - EREN, Fettah. "İskemik İnme Hastalarında Kan Lipid Parametreleri ve İntraserebral Hemoraji Gelişimi Arasındaki İlişki". Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 8/2 (2021), 297-304. https://doi.org/10.34087/cbusbed. 819759