Background and Aims: In this study, we investigated the usefulness ofthe ascites sodium level for prognostic purposes and its association with2-year mortality, spontaneous bacterial peritonitis, hepatic encephalopathy, and hepatorenal syndrome. Material and Methods: This study wasperformed between July and October 2018 in patients with liver cirrhosis in whom the ascites sodium level was studied. Patients with severeheart failure, nephrotic syndrome, or electrolyte disturbance; patientswho had spontaneous bacterial peritonitis, hepatic encephalopathy orhepatorenal syndrome at admission; and patients who used diureticsfor another reason were excluded from the study. Results: The studypopulation consisted of 72 cirrhotic patients [32 females (44.4%) and 40males (55.6%)]. The patients were followed up for 2 years, and mortalitydeveloped in 33 patients (45.8%). During follow-up, hepatic encephalopathy developed in 13 patients (18.1%), hepatorenal syndrome in 13patients (18.1%), and spontaneous bacterial peritonitis in 32 patients(44.4%). Hepatic encephalopathy, hepatorenal syndrome, and the spontaneous bacterial peritonitis ratio were higher in the deep hyponatremiagroup compared with other hyponatremia groups (p < 0.05). The meanChild-Pugh and Model for End-Stage Liver Disease-Na scores were similarin the moderate and deep hyponatremia groups, and they were higherthan in the other groups (p < 0.05). The mortality rate was found to behigher in the deep hyponatremia group than in the other hyponatremiagroups (p < 0.05). Hyponatremia in ascites was found to be an independent predictor of mortality, and patients in the deep hyponatremiagroup had a 29.55-fold increased risk of mortality compared with thosepatients without hyponatremia. Conclusion: In this study, it was shownthat deep hyponatremia less than 125 mEq/L in ascites was associatedwith increased cirrhotic complications and mortality