Nahide GÜNAY
(Kayseri Şehir Eğitim ve Araştırma Hastanesi, Sağlık Bilimleri Üniversitesi, Klinik Biyokimya Anabilim Dalı, Kayseri, Türkiye)
Nurullah GÜNAY
(Erciyes Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Kayseri, Türkiye)
Yıl: 2020Cilt: 45Sayı: 1ISSN: 1303-829X / 1303-829XSayfa Aralığı: 65 - 75İngilizce

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The distribution indices of erythrocytes: which one for acute ischemic stroke?
Background: The erythrocytes distribution indices are reported from same histogram but they have different ref- erence intervals and calculated by distinct measurements. Objectives: To explore whether the RDW-CV and RDW-SD values may predictive and prognostic significance in ischemic stroke patients and to clarify the relation each of these indices with stroke severity and 3-months survival. Materials and methods: Cumulative survival rates were calculated with the Kaplan-Meier method, and life curves were compared to RDW-CV, RDW-SD quartiles. The risk factors were described with a multivariable cox propor- tional hazard model. Results: In acute ischemic stroke, RDW-CV was more spe- cific and RDW-SD was more sensitive (92% vs. 80%) (52% vs. 48%). RDW-CV values higher than 14.7% are associ- ated with 11-fold increase in the risk of stroke; and the level of RDW-CV does show a linear relationship with the severity of stroke. However, when we evaluated RDW-SD, higher 43.55 fL RDW-SD values was have 16-fold increase in severity of stroke and have a relatively high linear rela- tionship with stroke severity scores to RDW-CV. Conclusions: RDW-CV and RDW-SD levels have different prognostic poor outcomes for interpreting in ischemic stroke events approach and these should be used alone and com- paratively with the AIS predictive and prognostic approach.
DergiAraştırma MakalesiErişime Açık
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