Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski
Yıl: 2020 Cilt: 31 Sayı: 4 Sayfa Aralığı: 225 - 231 Metin Dili: Türkçe DOI: 10.5080/u25270 İndeks Tarihi: 24-09-2021
Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski
Öz: Amaç: Bipolar bozuklukta (BB) kardiyovasküler hastalıklara (KVH)bağlı ölüm oranı genel popülasyona göre iki kat yüksek olduğu hâlde,hastaların KVH için tedavi başvuruları düşüktür. Bu çalışmada bipolarbozukluk tip-I tanılı hastaların klinik değişkenleri ve egzersiz özellikleriyle10 yıllık KVH riski ilişkisini değerlendirmek amaçlanmıştır.Yöntem: Araştırma Bakırköy Ruh ve Sinir Hastalıkları Hastanesi veSelçuk Üniversitesi Tıp Fakültesi Duygudurum Merkezlerinden takipedilen 106 ötimik bipolar bozukluk tip-I hastası ile yürütülmüştür.Hastaların fiziksel etkinlikleri Godin Boş Zaman Egzersiz Anketi ile 10yıllık KVH riskleri ise QRISK®2-2017 algoritması ile değerlendirilmiştir.Bulgular: Yaş ortalaması 39,5±8,6 yıl olan hastaların QRISK2 puanortalaması %3,64±0,46 olarak bulundu. Cinsiyete göre hastalarınQRISK2 puan ortalaması arasında fark saptanmadı. Hastaların sağlıklıkalp yaşı (QAGE) ortalaması şu anki yaşlarının ortalamasından8,49±6,46 yıl daha ileride bulundu. Godin egzersiz anketi toplampuanı ile QRISK2 puanları arasında düşük ve negatif yönde bir ilişkivardı (r=-0,168) fakat istatistiksel olarak anlamlı bulunmadı. Hastalıkbaşlangıç yaşı (RR:1,18; %95GA:1,09-1,28), tedavi süresi (RR:1,16;%95GA:1,05-1,29) ve tedavide atipik antipsikotik olması (RR:5,99;%95GA:1,12-31,90) ile kategorik QRISK2 puan derecelendirilmesiarasında pozitif yönde ve anlamlı düzeyde ilişki bulunmuştur.Sonuç: Bu çalışmada BB tanılı hastaların tedavisinde atipik antipsikotikolması ile QRISK2 arasında kuvvetli bir ilişki bulunmuştur. KVHgelişme riski yüksek olan BB tanılı hastaların belirlenmesi; bu hastalarıntedavilerinin gözden geçirilmesi ve koruyucu yaklaşımlar için teşvikedilmesi KVH’ya bağlı mortaliteyi azaltmak için önemlidir.
Anahtar Kelime: Ten-Year Risk of Cardiovascular Disease in Patients with Bipolar Disorder
Öz: Objective: Patients with bipolar disorder (BPD) are less likely to seek treatment for cardiovascular diseases (CVD) despite the two fold increased CVD-related death rate in BPD. The aim of this study was to evaluate the relationship between clinical variables, exercise characteristics and 10-year risk of CVD in patients with bipolar I disorder (BPD-I). Method: The study was carried out with 106 euthymic BPD-I patients who were followed up at the Mood Disorders Centers of Bakırköy Hospital for Mental and Neurological Diseases and Selcuk University Faculty of Medicine. The physical activity status of the patients were evaluated with the Godin Leisure-Time Exercise Questionnaire (GLTEQ) and the prospective 10-year risk of CVD was assessed by the QRISK®2-2017 - CVD risk algorithm. Results: Mean age of the patients were 39.5±8.6 years. The mean QRISK2 score of the patients was 3.64±0.46 %, which did not differ with respect to the gender. Patients’ mean healthy heart age (QAGE) was 8.49±6.46 years ahead of their current age. There was a weak negative correlation between GLTEQ total score and QRISK2 score (r= 0.168), but this was not statistically significant. However, statistically significant positive correlations were determined between the categorical QRISK2 score and the disease age of onset (RR:1.18; 95%CI:1.09-1.28), treatment duration (RR:1.16; 95%CI:1.05-1.29) and the inclusion of atypical antipsychotic agents in the treatment received (RR:5.99; 95%CI:1.12-31.90). Conclusion: A strong positive correlation was determined in this study between the QRISK2 score and the use of atypical antipsychotic drugs in the treatment of the BPD-I patients. It is important to identify patients diagnosed with bipolar disorder with a high risk of developing CVD to review the psychiatric treatment and to encourage the patients for preventive approaches.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | ince b, Altinbas K (2020). Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski. , 225 - 231. 10.5080/u25270 |
| Chicago | ince bahri,Altinbas Kursat Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski. (2020): 225 - 231. 10.5080/u25270 |
| MLA | ince bahri,Altinbas Kursat Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski. , 2020, ss.225 - 231. 10.5080/u25270 |
| AMA | ince b,Altinbas K Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski. . 2020; 225 - 231. 10.5080/u25270 |
| Vancouver | ince b,Altinbas K Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski. . 2020; 225 - 231. 10.5080/u25270 |
| IEEE | ince b,Altinbas K "Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski." , ss.225 - 231, 2020. 10.5080/u25270 |
| ISNAD | ince, bahri - Altinbas, Kursat. "Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski". (2020), 225-231. https://doi.org/10.5080/u25270 |
| APA | ince b, Altinbas K (2020). Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski. Türk Psikiyatri Dergisi, 31(4), 225 - 231. 10.5080/u25270 |
| Chicago | ince bahri,Altinbas Kursat Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski. Türk Psikiyatri Dergisi 31, no.4 (2020): 225 - 231. 10.5080/u25270 |
| MLA | ince bahri,Altinbas Kursat Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski. Türk Psikiyatri Dergisi, vol.31, no.4, 2020, ss.225 - 231. 10.5080/u25270 |
| AMA | ince b,Altinbas K Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski. Türk Psikiyatri Dergisi. 2020; 31(4): 225 - 231. 10.5080/u25270 |
| Vancouver | ince b,Altinbas K Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski. Türk Psikiyatri Dergisi. 2020; 31(4): 225 - 231. 10.5080/u25270 |
| IEEE | ince b,Altinbas K "Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski." Türk Psikiyatri Dergisi, 31, ss.225 - 231, 2020. 10.5080/u25270 |
| ISNAD | ince, bahri - Altinbas, Kursat. "Bipolar Bozukluk Tanılı Hastalarda 10 Yıllık Kardiyovasküler Hastalık Riski". Türk Psikiyatri Dergisi 31/4 (2020), 225-231. https://doi.org/10.5080/u25270 |
