Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women
Yıl: 2020 Cilt: 10 Sayı: 4 Sayfa Aralığı: 642 - 649 Metin Dili: İngilizce DOI: 10.31832/smj.791258 İndeks Tarihi: 06-10-2021
Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women
Öz: Objective There is a role of inflammatory processes on the pathophysiology of rheumatic heart valve disease (RHVD). The neutrophil-lymphocyte ratio (NLR) as an inflammatorymarker is associated with some clinical situations in pregnancy. In this study, we aimed to investigate the predictive role of NLR in pregnant women with NLR.Materials and MethodsFirst-trimester pregnant women, who were referred to cardiology outpatient clinic and diagnosed with RHVD (n=24) were enrolled in this study and age-matched healthypregnant women (n=24) were taken as control groups. The two groups were compared in terms of clinical characteristics, echocardiographic findings, and NLR. The roleof NLO in predicting RKKH has been examined.Results Groups were similar in terms of demographic features. NLR was higher in pregnant women with RHVD than the control group (3.68 ±1.74 vs. 2.68±1.14, p=0.00239). NLR(OR: 0,597, p= 0,037, 95% CI: 0,343-0,921) and neutrophil count (OR: 0,609, p= 0.013, 95% CI: 0,390-0,863) were possible independent predictors of RHVD.Conclusion NLR was significantly higher among pregnant women with RHVD. As it is not possible to provide routine cardiac check-up to all pregnant women; markers for specificrisk groups need to be defined to reduce the risks associated with heart diseases during pregnancy. According to these findings, pregnant women with high NLR may needextra attention in terms of CVD like RHVD. Further studies with large patient groups are needed to define the predictive value of NLR.
Anahtar Kelime: Nötrofil-Lenfosit Oranının Hamile Kadınlarda Romatizmal Kalp Kapağı Hastalığını Öngörme Yeteneği
Öz: Amaç Enflamatuar süreçlerin, romatizmal kalp kapağı hastalığı (RKKH) patofizyolojisi üzerinde bir rolü vardır. Enflamatuar bir belirteç olarak nötrofil-lenfosit oranı (NLO), gebelikte bazı klinik durumlarla ilişkilidir. Bu çalışmada, RKKH’li gebelerde NLO’nun prediktif rolünü araştırmayı amaçladık. Gereç ve Yöntemler Çalışmaya kardiyoloji polikliniğine sevk edilen ve RKKH tanısı alan (n = 24) birinci trimester gebeler alındı ve kontrol grubu olarak yaşları eşleşen sağlıklı gebeler (n = 24) alındı. İki grup klinik özellikler, ekokardiyografik bulgular ve NLO açısından karşılaştırıldı. NLO’nun RKKH’nı ön görmedeki rolü incelendi. Bulgular Gruplar demografik özellikler açısından benzerdi. NLO RKKH’lı kadınlarda kontrol grubuna göre daha yüksekti (3.68 ± 1.74 ve 2.68 ± 1.14, p = 0.00239). NLO (OR: 0,597, p= 0,037, 95% CI: 0,343-0,921) ve nötrofil sayısı (OR: 0,609, p= 0.013, 95% CI: 0,390-0,863) RKKH’nın olası bağımsız prediktörleriydi. Sonuç NLO RKKH olan gebe kadınlarda anlamlı olarak daha yüksekti. Tüm hamile kadınlara rutin kardiyak muayene sağlamak mümkün olmadığından; hamilelik sırasında kalp hastalıkları ile ilişkili riskleri azaltmak için spesifik risk grupları için belirteçlerin tanımlanması gerekir. Bu bulgulara göre, yüksek NLO’lı gebe kadınların RKKH gibi KVH açısından daha fazla dikkat göstermeleri gerekebilir. NLO’nın prediktif değerini tanımlamak için geniş hasta gruplarıyla daha ileri çalışmalara ihtiyaç vardır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | BOZKAYA V, Oskovi Kaplan Z, Engin-Ustun Y (2020). Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women. , 642 - 649. 10.31832/smj.791258 |
| Chicago | BOZKAYA VECİHA ÖZLEM,Oskovi Kaplan Zeynep Aslı,Engin-Ustun Yaprak Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women. (2020): 642 - 649. 10.31832/smj.791258 |
| MLA | BOZKAYA VECİHA ÖZLEM,Oskovi Kaplan Zeynep Aslı,Engin-Ustun Yaprak Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women. , 2020, ss.642 - 649. 10.31832/smj.791258 |
| AMA | BOZKAYA V,Oskovi Kaplan Z,Engin-Ustun Y Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women. . 2020; 642 - 649. 10.31832/smj.791258 |
| Vancouver | BOZKAYA V,Oskovi Kaplan Z,Engin-Ustun Y Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women. . 2020; 642 - 649. 10.31832/smj.791258 |
| IEEE | BOZKAYA V,Oskovi Kaplan Z,Engin-Ustun Y "Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women." , ss.642 - 649, 2020. 10.31832/smj.791258 |
| ISNAD | BOZKAYA, VECİHA ÖZLEM vd. "Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women". (2020), 642-649. https://doi.org/10.31832/smj.791258 |
| APA | BOZKAYA V, Oskovi Kaplan Z, Engin-Ustun Y (2020). Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women. Sakarya Tıp Dergisi, 10(4), 642 - 649. 10.31832/smj.791258 |
| Chicago | BOZKAYA VECİHA ÖZLEM,Oskovi Kaplan Zeynep Aslı,Engin-Ustun Yaprak Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women. Sakarya Tıp Dergisi 10, no.4 (2020): 642 - 649. 10.31832/smj.791258 |
| MLA | BOZKAYA VECİHA ÖZLEM,Oskovi Kaplan Zeynep Aslı,Engin-Ustun Yaprak Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women. Sakarya Tıp Dergisi, vol.10, no.4, 2020, ss.642 - 649. 10.31832/smj.791258 |
| AMA | BOZKAYA V,Oskovi Kaplan Z,Engin-Ustun Y Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women. Sakarya Tıp Dergisi. 2020; 10(4): 642 - 649. 10.31832/smj.791258 |
| Vancouver | BOZKAYA V,Oskovi Kaplan Z,Engin-Ustun Y Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women. Sakarya Tıp Dergisi. 2020; 10(4): 642 - 649. 10.31832/smj.791258 |
| IEEE | BOZKAYA V,Oskovi Kaplan Z,Engin-Ustun Y "Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women." Sakarya Tıp Dergisi, 10, ss.642 - 649, 2020. 10.31832/smj.791258 |
| ISNAD | BOZKAYA, VECİHA ÖZLEM vd. "Capibility of Neuthrophil-lymphocyte Ratio to Predict Rheumatic Heart Valve Disease In Pregnant Women". Sakarya Tıp Dergisi 10/4 (2020), 642-649. https://doi.org/10.31832/smj.791258 |
