Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study

ZEYBEK, Dilara; ALTUN, Huseyin; USTUN, Onur; GURPİNAR, Berk; HANCİ, Deniz

Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study

Deniz Hanci, (ürkiye Sağlık Bilimleri Üniversitesi, Prof. Dr. Cemil Taşçıoğlu Şehir Hastanesi, Kulak Burun Boğaz Kliniği, İstanbul, Türkiye)

Huseyin Altun, (Yunus Emre Hastanesi, Kulak Burun Boğaz Kliniği, İstanbul, Türkiye)

Onur Ustun, (Türkiye Sağlık Bilimleri Üniversitesi, Haseki Eğitim ve Araştırma Hastanesi, Kulak Burun Boğaz Kliniği İstanbul, Türkiye)

Dilara Zeybek, (Hacettepe Üniversitesi Tıp Fakültesi Histoloji ve Embriyoloji Anabilim Dalı, Ankara, Türkiye)

Berk Gurpinar (Türkiye Sağlık Bilimleri Üniversitesi, Prof. Dr. Cemil Taşçıoğlu Şehir Hastanesi, Kulak Burun Boğaz Kliniği, İstanbul, Türkiye)

Haseki Tıp Bülteni

5 0

Yıl: 2021 Cilt: 59 Sayı: 4 Sayfa Aralığı: 268 - 272 Metin Dili: İngilizce İndeks Tarihi: 04-11-2021

Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study

Öz:

Aim: Following septoplasty surgery, nasal packing is performed to stabilize the healing of septum and prevent septal hematoma. Thepurpose of this study was to investigate the efficacy of fibrin glue, 2-octyl cyanoacrylate, and n-butyl cyanoacrylate on the healing ofthe septum cartilage following septoplasty.Methods: Since rabbit ear cartilages resemble septal cartilage, 10 New Zealand rabbits were used in our study which was performedbetween March and May 2016. A total of 20 ears of 10 rabbits were used, with 4 separate incisions in each ear. Perichondrial flapswere raised and the following chemical adhesives were applied separately on the cartilage: Fibrin glue, 2-octyl cyanoacrylate, n-butylcyanoacrylate. As the control group, no material was applied to the remaining incision. The right ears were examined at 15 days and theleft ears at 30 days; samples were removed with solid tissue around the edges, treated with formol and histopathologically examined.Results: Epithelial integrity and re-epithelialization were adequate in all groups. As the epithelium and perichondrium thicknesses werecompared in the 15-day samples, epithelium and perichondrium were thicker in the n-butyl cyanoacrylate and 2-octyl cyanoacrylategroups than the other groups.Conclusion: N-butyl cyanoacrylate, fibrin glue and 2-octyl cyanoacrylate are potential alternatives for cartilage and mucosal support.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	HANCİ D, ALTUN H, USTUN O, ZEYBEK D, GURPİNAR B (2021). Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study. , 268 - 272.
Chicago	HANCİ Deniz,ALTUN Huseyin,USTUN Onur,ZEYBEK Dilara,GURPİNAR Berk Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study. (2021): 268 - 272.
MLA	HANCİ Deniz,ALTUN Huseyin,USTUN Onur,ZEYBEK Dilara,GURPİNAR Berk Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study. , 2021, ss.268 - 272.
AMA	HANCİ D,ALTUN H,USTUN O,ZEYBEK D,GURPİNAR B Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study. . 2021; 268 - 272.
Vancouver	HANCİ D,ALTUN H,USTUN O,ZEYBEK D,GURPİNAR B Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study. . 2021; 268 - 272.
IEEE	HANCİ D,ALTUN H,USTUN O,ZEYBEK D,GURPİNAR B "Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study." , ss.268 - 272, 2021.
ISNAD	HANCİ, Deniz vd. "Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study". (2021), 268-272.

APA	HANCİ D, ALTUN H, USTUN O, ZEYBEK D, GURPİNAR B (2021). Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study. Haseki Tıp Bülteni, 59(4), 268 - 272.
Chicago	HANCİ Deniz,ALTUN Huseyin,USTUN Onur,ZEYBEK Dilara,GURPİNAR Berk Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study. Haseki Tıp Bülteni 59, no.4 (2021): 268 - 272.
MLA	HANCİ Deniz,ALTUN Huseyin,USTUN Onur,ZEYBEK Dilara,GURPİNAR Berk Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study. Haseki Tıp Bülteni, vol.59, no.4, 2021, ss.268 - 272.
AMA	HANCİ D,ALTUN H,USTUN O,ZEYBEK D,GURPİNAR B Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study. Haseki Tıp Bülteni. 2021; 59(4): 268 - 272.
Vancouver	HANCİ D,ALTUN H,USTUN O,ZEYBEK D,GURPİNAR B Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study. Haseki Tıp Bülteni. 2021; 59(4): 268 - 272.
IEEE	HANCİ D,ALTUN H,USTUN O,ZEYBEK D,GURPİNAR B "Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study." Haseki Tıp Bülteni, 59, ss.268 - 272, 2021.
ISNAD	HANCİ, Deniz vd. "Effects of Fibrin Glue, 2-Octyl Cyanoacrylate, and N-Butyl Cyanoacrylate on Cartilage Healing: An Experimental Animal Study". Haseki Tıp Bülteni 59/4 (2021), 268-272.