Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol

HOSSEİNİ, Seyed Ali; ARJMAND, Ayat; ABEDİ, Bahram

Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol

Ayat Arjmand, (Beden Eğitimi Bölümü ve Spor Bilimleri, Mahallat Şubesi, İslami Azad Üniversite, Mahallat, İran)

Bahram Abedi, (Beden Eğitimi Bölümü ve Spor Bilimleri, Mahallat Şubesi, İslami Azad Üniversite, Mahallat, İran)

Seyed Ali Hosseini (Spor Fizyolojisi Anabilim Dalı, Marvdaşt Şube, İslami Azad Üniversitesi, Marvdaşt, İran)

Eurasian Journal of Medicine

5 0

Yıl: 2021 Cilt: 53 Sayı: 2 Sayfa Aralığı: 79 - 84 Metin Dili: İngilizce İndeks Tarihi: 09-10-2021

Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol

Öz:

Objective: Nowadays, the use of energetic substances has become a complex problem in sports, such thatthe role of anabolic-androgenic steroids is undeniable. This study aimed to investigate the antiapoptotic effectof resistance training and Tribulus terrestris in the heart tissue of rats exposed to stanozolol.Materials and Methods: 35 rats divided into 7 groups including (1) sham , (2) stanozolol-treated, (3)stanozolol+50 mg/kg Tribulus terrestris-treated, (4) stanozolol+100 mg/kg Tribulus terrestris-treated, (5)stanozolol+resistance training-treated, (6) stanozolol+resistance training+50 mg/kg Tribulus terrestris-treated, and (7) stanozolol+resistance training+100 mg/kg Tribulus terrestris-treated. During 8 weeks, groups 2-7received 5 mg/kg stanozolol per day peritoneally; groups 5-7 performed resistance training for 3 sessions perweek; and groups 3, 4, 6 and 7 received daily doses of Tribulus terrestris peritoneally.Results: Stanozolol administration significantly increased the BAX, BCL-2, P53, and caspase 3 and BAX/BCL2 ratio (P < .001). Resistance training, 100 mg/kg Tribulus terrestris administration, 50 mg/kg Tribulus terrestrisadministration, resistance training+100 mg/kg Tribulus terrestris administration, and resistance training+50mg/kg Tribulus terrestris administration significantly decreased BAX, BCL-2, P53, and caspase 3 levels andBAX/BCL-2 ratio (P < .001); however, stanozolol+resistance training+100 mg/kg Tribulus terrestris administration caused more decrease than stanozolol+resistance training+50 mg/kg Tribulus terrestris administrationin BAX (P < .001).Conclusion: Resistance training and Tribulus terrestris administration alone appear to have antiapoptotic effects; however, resistance training combined with Tribulus terrestris administration, especially at higher doses,have more desirable effects than resistance training or Tribulus terrestris administration alone on the apoptosismarkers.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ARJMAND A, ABEDİ B, HOSSEİNİ S (2021). Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol. , 79 - 84.
Chicago	ARJMAND Ayat,ABEDİ Bahram,HOSSEİNİ Seyed Ali Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol. (2021): 79 - 84.
MLA	ARJMAND Ayat,ABEDİ Bahram,HOSSEİNİ Seyed Ali Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol. , 2021, ss.79 - 84.
AMA	ARJMAND A,ABEDİ B,HOSSEİNİ S Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol. . 2021; 79 - 84.
Vancouver	ARJMAND A,ABEDİ B,HOSSEİNİ S Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol. . 2021; 79 - 84.
IEEE	ARJMAND A,ABEDİ B,HOSSEİNİ S "Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol." , ss.79 - 84, 2021.
ISNAD	ARJMAND, Ayat vd. "Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol". (2021), 79-84.

APA	ARJMAND A, ABEDİ B, HOSSEİNİ S (2021). Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol. Eurasian Journal of Medicine, 53(2), 79 - 84.
Chicago	ARJMAND Ayat,ABEDİ Bahram,HOSSEİNİ Seyed Ali Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol. Eurasian Journal of Medicine 53, no.2 (2021): 79 - 84.
MLA	ARJMAND Ayat,ABEDİ Bahram,HOSSEİNİ Seyed Ali Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol. Eurasian Journal of Medicine, vol.53, no.2, 2021, ss.79 - 84.
AMA	ARJMAND A,ABEDİ B,HOSSEİNİ S Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol. Eurasian Journal of Medicine. 2021; 53(2): 79 - 84.
Vancouver	ARJMAND A,ABEDİ B,HOSSEİNİ S Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol. Eurasian Journal of Medicine. 2021; 53(2): 79 - 84.
IEEE	ARJMAND A,ABEDİ B,HOSSEİNİ S "Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol." Eurasian Journal of Medicine, 53, ss.79 - 84, 2021.
ISNAD	ARJMAND, Ayat vd. "Anti-Apoptotic Effects of Resistance Training and Tribulus Terrestris Consumption in the Heart Tissue of Rats Exposed to Stanozolol". Eurasian Journal of Medicine 53/2 (2021), 79-84.