Yıl: 2021 Cilt: 4 Sayı: 3 Sayfa Aralığı: 175 - 180 Metin Dili: İngilizce DOI: 10.30714/j-ebr.2021370071 İndeks Tarihi: 08-10-2021

The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses

Öz:
Aim:To evaluate the possible effects of SARS-CoV-2 infection on retinal nerve fiber layer (RNFL) and ganglion cell complex layer (GC-IPL) thicknesses. Method: Patients who had been infected by SARS-CoV-2 and hospitalized because of severe pneumonia were found out from the database of COVID-19 pandemic hospital and formed the patient group. The control group was composed of non-COVID-19 age-matched subjects. The mean and fragmented RNFL and GC-IPL thicknesses were measured by optical coherence tomography (OCT), and compared between two groups, statistically. Results: Patient group 34 eyes of 34 subjects (18 male, 16 female) and 31 eyes of 31 subjects (14 male, 17 female) in the control group were enrolled. The mean age and gender were not statistically different between groups (p:0.56, 0,57, respectively).A statistically significant difference was not found between groups in terms of mean, superior, inferior, temporal, nasal RNFL thicknesses and mean superior, inferior, temporal, and nasal GC-IPL thicknesses. Conclusion: The mean and fragmented RNFL and GC-IPL thicknesses measured by OCT were not statistically different in patients who had moderate disease course and recovered from COVID-19 infection.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • [1]Talevi D, Socci V, Carai M, et al. Mental health outcomes of the CoViD-19 pandemic. Riv Psichiatr. 2020;55(3):137-144.
  • [2]Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun. 2020;109:102433.
  • [3]Wang W, Tang J, Wei F. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China. J Med Virol. 2020;92(4):441–47.
  • [4]Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506.
  • [5]Dockery DM, Rowe SG, Murphy MA, et al. The Ocular Manifestations and Transmission of COVID-19: Recommendations for Prevention. J Emerg Med. 2020;59(1):137-140.
  • [6]Wu P, Duan F, Luo C, et al. Characteristics of Ocular Findings of Patients With Coronavirus Disease 2019 (COVID-19) in Hubei Province, China. JAMA Ophthalmol. 2020;138(5):575-78.
  • [7]Öncül H, Öncül FY, Alakus MF, et al. Ocular findings in patients with coronavirus disease 2019 (COVID-19) in an outbreak hospital. J Med Virol. 2021;93(2):1126-32.
  • [8]Savastano A, Crincoli E, Savastano MC, et al. Against Covid-Post-Acute Care Study Group. Peripapillary Retinal Vascular Involvement in Early Post-COVID-19 Patients. J Clin Med. 2020;9(9):2895.
  • [9]Benito-Pascual B, Gegúndez JA, Díaz-Valle D, et al. Panuveitis and Optic Neuritis as a Possible Initial Presentation of the Novel Coronavirus Disease 2019 (COVID-19). Ocul Immunol Inflamm. 2020;28(6):922-25.
  • [10]Cozzupoli GM, Savastano MC, Falsini B, et al. Possible Retinal Impairment Secondary to Ritonavir Use in SARS-CoV-2 Patients: A Narrative Systematic Review. J Ophthalmol. 2020;2020:5350494.
  • [11]Jia Y, Simonett JM, Wang J, et al. WideField OCT Angiography Investigation of the Relationship Between Radial Peripapillary Capillary Plexus Density and Nerve Fiber Layer Thickness. Invest Ophthalmol Vis Sci. 2017;58(12):5188-94.
  • [12]Mansoori T, Sivaswamy J, Gamalapati JS, et al. Radial Peripapillary Capillary Density Measurement Using Optical Coherence Tomography Angiography in Early Glaucoma. J Glaucoma. 2017;26(5):438-43.
  • [13]Marinho PM, Marcos AAA, Romano AC, et al. Retinal findings in patients with COVID19. Lancet. 2020;395(10237):1610.
  • [14]Burgos-Blasco B, Güemes-Villahoz N, Vidal-Villegas B, et al. Optic nerve and macular optical coherence tomography in recovered COVID-19 patients. Eur J Ophthalmol. 2021:11206721211001019.
  • [15]Krawitz BD, Sirinek P, Doobin D, et al. The Challenge of Managing Bilateral Acute Angle-closure Glaucoma in the Presence of Active SARS-CoV-2 Infection. J Glaucoma. 2021;30(3):e50-e53.
  • [16]Nerlikar RR, Palsule AC, Vadke S. Bilateral Acute Angle Closure Glaucoma after Prone Position Ventilation for COVID 19 Pneumonia. J Glaucoma. 2021. doi: 10.1097/IJG.0000000000001864
APA Özmen S, Çakır B, OKAN H, OZKAN AKSOY N, Guclu E (2021). The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses. , 175 - 180. 10.30714/j-ebr.2021370071
Chicago Özmen Sedat,Çakır Burçin,OKAN Hüseyin Doğuş,OZKAN AKSOY NILGÜN,Guclu Ertugrul The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses. (2021): 175 - 180. 10.30714/j-ebr.2021370071
MLA Özmen Sedat,Çakır Burçin,OKAN Hüseyin Doğuş,OZKAN AKSOY NILGÜN,Guclu Ertugrul The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses. , 2021, ss.175 - 180. 10.30714/j-ebr.2021370071
AMA Özmen S,Çakır B,OKAN H,OZKAN AKSOY N,Guclu E The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses. . 2021; 175 - 180. 10.30714/j-ebr.2021370071
Vancouver Özmen S,Çakır B,OKAN H,OZKAN AKSOY N,Guclu E The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses. . 2021; 175 - 180. 10.30714/j-ebr.2021370071
IEEE Özmen S,Çakır B,OKAN H,OZKAN AKSOY N,Guclu E "The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses." , ss.175 - 180, 2021. 10.30714/j-ebr.2021370071
ISNAD Özmen, Sedat vd. "The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses". (2021), 175-180. https://doi.org/10.30714/j-ebr.2021370071
APA Özmen S, Çakır B, OKAN H, OZKAN AKSOY N, Guclu E (2021). The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses. Experimental Biomedical Research, 4(3), 175 - 180. 10.30714/j-ebr.2021370071
Chicago Özmen Sedat,Çakır Burçin,OKAN Hüseyin Doğuş,OZKAN AKSOY NILGÜN,Guclu Ertugrul The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses. Experimental Biomedical Research 4, no.3 (2021): 175 - 180. 10.30714/j-ebr.2021370071
MLA Özmen Sedat,Çakır Burçin,OKAN Hüseyin Doğuş,OZKAN AKSOY NILGÜN,Guclu Ertugrul The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses. Experimental Biomedical Research, vol.4, no.3, 2021, ss.175 - 180. 10.30714/j-ebr.2021370071
AMA Özmen S,Çakır B,OKAN H,OZKAN AKSOY N,Guclu E The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses. Experimental Biomedical Research. 2021; 4(3): 175 - 180. 10.30714/j-ebr.2021370071
Vancouver Özmen S,Çakır B,OKAN H,OZKAN AKSOY N,Guclu E The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses. Experimental Biomedical Research. 2021; 4(3): 175 - 180. 10.30714/j-ebr.2021370071
IEEE Özmen S,Çakır B,OKAN H,OZKAN AKSOY N,Guclu E "The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses." Experimental Biomedical Research, 4, ss.175 - 180, 2021. 10.30714/j-ebr.2021370071
ISNAD Özmen, Sedat vd. "The effect of COVID-19 infection on retinal nerve fiber layer and ganglion cell complexlayer thicknesses". Experimental Biomedical Research 4/3 (2021), 175-180. https://doi.org/10.30714/j-ebr.2021370071