Lettuce (Lactuca sativa L.) is a low-calorie, appetizing plant with low protein and fat content. Lettuce is grown both in Turkey and in the world under the open cover. Commercial lettuce production in the Aegean, Marmara and Mediterranean regions can be made in all seasons of the year except June, July and August. Zinc (Zn) is an important micro element for plants and zinc deficiency is the most common micro element insufficiency in the world. Zinc insufficiency is also important for the sustainability of food production since it affects the yield and quality of the plant. In order to prevent the insufficiency of this micro element, zinc application from both soil and foliar applications are used. In this study, it was aimed to determine the effect of zinc applications on some leaf nutrient element contents in lettuce plant at different doses from soil ($Zn_{T0}$=0; $Zn_{T1}$=10 ppm; $Zn_{T2}$=20 ppm; $Zn_{T3}$=30 ppm) and leaf ($Zn_{Y0}$=0; $Zn_{Y1}$= 0.10 %; $Zn_{Y2}$=0.20 %; $Zn_{Y3}$= 0.30 % as three times )in the form of $ZnSO_47H_2O$.As a result; the effects of the increasing doses of both soil and foliar applications on Mg, Zn, Mn and Cu contents of lettuce plant were determined to be statistically significant differences (P<0.05). In terms of both soil and foliar Zn applications $Zn_{T2}$=20 ppm and $Zn_{Y2}$= 0.20 % can be recommended for Zn contents of lettuce plant.