Two decades of research on autoimmune liver disease in Turkey

EKIN, NAZIM; Demir, Nurhan; efe, cumali; TORGUTALP, MURAT; Wahlin, Staffan

doi:10.5152/tjg.2020.19866

Two decades of research on autoimmune liver disease in Turkey

Nurhan DEMİR, (Diyarbakır Sağlık Bilimleri Üniversitesi, Eğitim ve Araştırma Hastanesi, Gastroenteroloji Anabilim Dalı, Diyarbakır, Türkiye)

Nazim EKIN, (Diyarbakır Sağlık Bilimleri Üniversitesi, Eğitim ve Araştırma Hastanesi, Gastroenteroloji Anabilim Dalı, Diyarbakır, Türkiye)

Murat TORGUTALP, (Ankara Üniversitesi, İbni-Sina Hastanesi, Romatoloji Anabilim Dalı, Ankara, Türkiye)

Staffan WAHLIN, (Karolinska Institutet and Karolinska University Hospital, Centre for Digestive Diseases, Division of Hepatology, Sweden)

Cumali EFE (Harran Üniversitesi, Tıp Fakültesi, Gastroenteroloji Anabilim Dalı, Şanlıurfa, Türkiye)

Turkish Journal of Gastroenterology

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Yıl: 2020 Cilt: 31 Sayı: 12 Sayfa Aralığı: 877 - 882 Metin Dili: İngilizce DOI: 10.5152/tjg.2020.19866 İndeks Tarihi: 19-10-2021

Two decades of research on autoimmune liver disease in Turkey

Öz:

Background/Aims: Autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC) are the 3 mainautoimmune liver diseases (AILDs). The epidemiology of AILD in Turkey is not known. To determine the scientific status, we performed a scientometric analysis of AILD-related original articles that originated from Turkey.Materials and Methods: We searched the Web of Science database, the Science Citation Index Expanded (SCI-E), and the Social Sciences Citation Index (SSCI) by using the keywords “autoimmune hepatitis,” “primary biliary cholangitis/primary biliary cirrhosis,” and “primary sclerosingcholangitis” in conjunction with “Turkey.” A scientometric analysis was done on the search results.Results: We identified 117 AILD-related papers that were published in Turkey from 1997 to 2019. Among these, 70 case reports, letters, andreviews and 2 original articles that were not cited in SCI-E/SSCI were excluded. The remaining 45 original articles were further analyzed. Thesestudies were related to AIH (n=22), PBC (n=7), PSC (n=9), PBC-AIH overlap (n=5), and others (n=2). Four of the publications originated in pediatric settings; 9 of 45 papers were published from 1997 to 2008 and 36 papers were published from 2009 to 2019. Most papers (75%) werereported from 5 centers; 9 papers (20%) were published in journals with an impact factor of 3 or higher.Conclusion: The overall number and quality of AILD-related papers in Turkey are unexpectedly low, although a number of papers have receivedconsiderable international recognition. More epidemiologic, prospective, and multicenter research projects are warranted to advance AILDknowledge and to produce high-quality research from Turkey

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Vierling JM. Autoimmune Hepatitis and Overlap Syndromes: Diagnosis and Management. Clin Gastroenterol Hepatol 2015; 13: 2088- 108.
2. Younossi ZM, Bernstein D, Shiffman ML, et al. Diagnosis and Management of Primary Biliary Cholangitis. Am J Gastroenterol 2019; 114: 48-63.
3. Lindor KD, Kowdley KV, Harrison ME. ACG Clinical Guideline: Primary Sclerosing Cholangitis. Am J Gastroenterol 2015; 110: 646-59.
4. Manns MP, Czaja AJ, Gorham JD, et al. Diagnosis and management of autoimmune hepatitis. Hepatology 2010; 51: 2193-213.
5. Boonstra K, Beuers U, Ponsioen CY. Epidemiology of primary sclerosing cholangitis and primary biliary cirrhosis: a systematic review. J Hepatol 2012; 56: 1181-8.
6. Jepsen P, Grønbæk L, Vilstrup H. Worldwide Incidence of Autoimmune Liver Disease. Dig Dis 2015; 33: 2-12.
7. Adam R, Karam V, Delvart V, et al. Evolution of indications and results of liver transplantation in Europe. A report from the European Liver Transplant Registry (ELTR). J Hepatol 2012; 57: 675-88.
8. Tabak F, Yurdaydın C, Kaymakoğlu S, et al. Diagnosis, management and treatment of hepatitis B virus infection: Turkey 2017 Clinical Practice Guidelines. Turk J Gastroenterol 2017; 28: 73-83.
9. Kaymakoğlu S, Köksal İ, Tabak F, et al. Recommendation for treatment of hepatitis C virus infection. Turk J Gastroenterol 2017; 28: 94-100.
10. Rezaee Zavareh MS, Alavian SM. Ten-year analysis of hepatitis-related papers in the Middle East: a web of science-based scientometric study. Turk J Gastroenterol 2017; 28: 20-5.
11. Kaya E, Yılmaz Y. Non-alcoholic fatty liver disease: A growing public health problem in Turkey. Turk J Gastroenterol 2019; 30: 865- 71.
12. Kaymakoglu S, Cakaloglu Y, Demir K, et al. Is severe cryptogenic chronic hepatitis similar to autoimmune hepatitis? J Hepatol 1998; 28: 78-83.
13. Efe C, Ozaslan E, Wahlin S, et al. Antibodies to soluble liver antigen in patients with various liver diseases: a multicentre study. Liver Int 2013; 33: 190-6.
14. Purnak T, Efe C, Kav T, Wahlin S, Ozaslan E. Treatment Response and Outcome with Two Different Prednisolone Regimens in Autoimmune Hepatitis. Dig Dis Sci 2017; 62: 2900-2907.
15. Efe C, Hagström H, Ytting H, et al. Efficacy and Safety of My cophenolate Mofetil and Tacrolimus as Second-line Therapy for Pa tients with Autoimmune Hepatitis. Clin Gastroenterol Hepatol. Clin Gastroenterol Hepatol 2017; 15: 1950-6.
16. Kuzu UB, Öztaş E, Turhan N, et al. Clinical and histological fea tures of idiosyncratic liver injury: Dilemma in diagnosis of autoim mune hepatitis. Hepatol Res 2016; 46: 277-91.
17. Ersöz G, Vardar R, Akarca US, et al. Ornidazole-induced autoim mune hepatitis. Turk J Gastroenterol 2011; 22: 494-9.
18. Efe C, Tascilar K, Henriksson I, et al. Validation of Risk Scoring Systems in Ursodeoxycholic Acid-Treated Patients with Primary Bil iary Cholangitis. Am J Gastroenterol 2019; 114: 1101-8.
19. Günsar F, Akarca US, Ersöz G, Karasu Z, Yüce G, Batur Y. Clinical and biochemical features and therapy responses in primary biliary cirrhosis and primary biliary cirrhosis-autoimmune hepatitis overlap syndrome. Hepatogastroenterology 2002; 49: 1195-200.
20. Efe C, Ozaslan E, Heurgué-Berlot A, et al. Sequential presen tation of primary biliary cirrhosis and autoimmune hepatitis. Eur J Gastroenterol Hepatol 2014; 26: 532-7.
21. Ozaslan E, Efe C, Akbulut S, et al. Therapy response and outcome of overlap syndromes: autoimmune hepatitis and primary biliary cir rhosis compared to autoimmune hepatitis and autoimmune cholan gitis. Hepatogastroenterology 2010; 57: 441-6.
22. Ozaslan E, Efe C, Heurgué-Berlot A, et al. Factors associated with response to therapy and outcome of patients with primary biliary cirrhosis with features of autoimmune hepatitis. Clin Gastroenterol Hepatol 2014; 12: 863-9.
23. Parlak E, Kosar Y, Ulker A, Dagli U, Alkim C, Sahin B. Primary scle rosing cholangitis in patients with inflammatory bowel disease in Turkey. J Clin Gastroenterol 2001; 33: 299-301.
24. Parlak E, Ciçek B, Dişibeyaz S, Köksal AS, Sahin B. An endoscopic finding in patients with primary sclerosing cholangitis: retraction of the main duodenal papilla into the duodenum wall. Gastrointest En dosc 2007; 65: 532-6.
25. Öztaş E, Özer Etik D, Metin RO, et al. Comparative assessment of prognostic value for revised-Mayo risk model and Child-Pugh score in patients with primary sclerosing cholangitis. Turk J Gastroenterol 2015; 26: 31-5.
26. Astarcioglu I, Egeli T, Unek T, et al. Liver Transplant in Patients with Primary Sclerosing Cholangitis: Long-Term Experience of a Sin gle Center. Exp Clin Transplant 2018; 16: 434-8.
27. Emek E, Serin A, Sahin T, et al. Experience in Liver Transplanta tion Due to Primary Sclerosing Cholangitis: A Single Center Experi ence. Transplant Proc 2019; 51: 2439-41.
28. Geylanı Güleç S, Urganci N, Polat TB, Demırel E, Yilmaz E. Rela tions between human leukocyte antigens and autoimmune hepati tis in Turkish children. Turk J Gastroenterol 2011; 22: 42-6.
29. Karakoyun M, Ecevit CO, Kilicoglu E, Aydogdu S, Yagci RV, Oz genc F. Autoimmune hepatitis and long-term disease course in chil dren in Turkey, a single-center experience. Eur J Gastroenterol Hepa tol 2016; 28: 927-30.
30. Aydemir Y, Akcoren Z, Demir H, Saltik Temizel IN, Ozen H, Yuce A. Clinical and histopathological features of immunoglobulin G4-as sociated autoimmune hepatitis in children. J Gastroenterol Hepatol 2019; 34: 742-6.
31. Efe C, Taii HA, Ytting H, et al. Tacrolimus and Mycophenolate Mofetil as Second-Line Therapies for Pediatric Patients with Auto immune Hepatitis. Dig Dis Sci 2018; 63: 1348-54.

APA	Demir N, EKIN N, TORGUTALP M, Wahlin S, efe c (2020). Two decades of research on autoimmune liver disease in Turkey. , 877 - 882. 10.5152/tjg.2020.19866
Chicago	Demir Nurhan,EKIN NAZIM,TORGUTALP MURAT,Wahlin Staffan,efe cumali Two decades of research on autoimmune liver disease in Turkey. (2020): 877 - 882. 10.5152/tjg.2020.19866
MLA	Demir Nurhan,EKIN NAZIM,TORGUTALP MURAT,Wahlin Staffan,efe cumali Two decades of research on autoimmune liver disease in Turkey. , 2020, ss.877 - 882. 10.5152/tjg.2020.19866
AMA	Demir N,EKIN N,TORGUTALP M,Wahlin S,efe c Two decades of research on autoimmune liver disease in Turkey. . 2020; 877 - 882. 10.5152/tjg.2020.19866
Vancouver	Demir N,EKIN N,TORGUTALP M,Wahlin S,efe c Two decades of research on autoimmune liver disease in Turkey. . 2020; 877 - 882. 10.5152/tjg.2020.19866
IEEE	Demir N,EKIN N,TORGUTALP M,Wahlin S,efe c "Two decades of research on autoimmune liver disease in Turkey." , ss.877 - 882, 2020. 10.5152/tjg.2020.19866
ISNAD	Demir, Nurhan vd. "Two decades of research on autoimmune liver disease in Turkey". (2020), 877-882. https://doi.org/10.5152/tjg.2020.19866

APA	Demir N, EKIN N, TORGUTALP M, Wahlin S, efe c (2020). Two decades of research on autoimmune liver disease in Turkey. Turkish Journal of Gastroenterology, 31(12), 877 - 882. 10.5152/tjg.2020.19866
Chicago	Demir Nurhan,EKIN NAZIM,TORGUTALP MURAT,Wahlin Staffan,efe cumali Two decades of research on autoimmune liver disease in Turkey. Turkish Journal of Gastroenterology 31, no.12 (2020): 877 - 882. 10.5152/tjg.2020.19866
MLA	Demir Nurhan,EKIN NAZIM,TORGUTALP MURAT,Wahlin Staffan,efe cumali Two decades of research on autoimmune liver disease in Turkey. Turkish Journal of Gastroenterology, vol.31, no.12, 2020, ss.877 - 882. 10.5152/tjg.2020.19866
AMA	Demir N,EKIN N,TORGUTALP M,Wahlin S,efe c Two decades of research on autoimmune liver disease in Turkey. Turkish Journal of Gastroenterology. 2020; 31(12): 877 - 882. 10.5152/tjg.2020.19866
Vancouver	Demir N,EKIN N,TORGUTALP M,Wahlin S,efe c Two decades of research on autoimmune liver disease in Turkey. Turkish Journal of Gastroenterology. 2020; 31(12): 877 - 882. 10.5152/tjg.2020.19866
IEEE	Demir N,EKIN N,TORGUTALP M,Wahlin S,efe c "Two decades of research on autoimmune liver disease in Turkey." Turkish Journal of Gastroenterology, 31, ss.877 - 882, 2020. 10.5152/tjg.2020.19866
ISNAD	Demir, Nurhan vd. "Two decades of research on autoimmune liver disease in Turkey". Turkish Journal of Gastroenterology 31/12 (2020), 877-882. https://doi.org/10.5152/tjg.2020.19866