Objective: Metastatic tumors of the bone are more frequent than primary malignant bone tumors. In the present study, we aimed to investigate the frequency of metastatic bone tumors and its relation with patient age, sex, tumor location and symptoms. Material and Methods: One hundred and twenty nine patients included the study biopsied or operated at Selcuk University Faculty of Medicine Orthopedics and Traumatology Department and diagnosed at Pathology Department between January 2009 and December 2017. Results and Conclusions:In the present study, the mean age of the patients is 64.8. Of the patients, one hundred and twelve (87%) are older than 50 years old. 42% of patients under 50 years old are diagnosed as metastatic breast cancer. In women, most frequent metastatic bone tumors are breast (43%), tumors with unknown primary origin (16%), lung (14%) and kidney (9%), while in men they were as; lung (35%), prostate (15%), kidney (11%) and tumors with unknown primary origin (9%). The most frequent metastatic sites in bone are; femur (33%), vertebrae (25%) and humerus (18%), respectively. Pain is the most frequent presentation symptom with 84% frequency. Bone fracture in long bones as femur, humerus and tibia accompanies to pain. The presentation sypmtom was fracture in 37% of the cases. Of those, the fracture was due to lung cancer in 11 (30%), breast cancer in 9 (24%), renal cell carcinoma in 4 (%10) and prostate cancer in 2 (5%) of the cases. In our study, the rate of the tumors with unknown primary origin is higher than the literature.