Yıl: 2021 Cilt: 45 Sayı: 1 Sayfa Aralığı: 21 - 27 Metin Dili: İngilizce İndeks Tarihi: 15-11-2021

Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever

Öz:
Objective: Health-related quality of life (HRQOL) is a concept that assesses the effects of physical symptoms, functional status, andcurrent illness on psychological and social functioning. In this study, we aimed to examine the quality of life in children and adolescentswith familial Mediterranean fever (FMF) according to personal and disease-related factors.Methods: A total of 257 children and adolescents with FMF aged 8–18 years were included in the study. The Juvenile Auto-inflammatory Disease Multidimensional Assessment Report was used for assessment of functional ability (self-report scale), pain (visual analog scale - VAS), therapeutic compliance, and HRQOL (physical, social, school, and emotional status). An increase in all subscale scores indicated a worsening.Results: The mean age of the patients was 12.4±2.63 years, and 132 (51.4%) of them were women. In adolescents, HRQOL-general,-social, -school, and -emotional scores were higher than children (p<0.001 for all). Also, all HRQOL subscale scores of females weresignificantly higher than males (p<0.05 for all). Patients who had an attack in the last month had higher functional ability, pain, and allHRQOL subscale scores. However, patients with and without exertional leg pain had similar results in terms of all HRQOL subscales. TheVAS pain score was positively correlated with HRQOL-general, -physical, -school, and -emotional scores. The therapeutic compliancescores were positively weakly correlated with all HRQOL subscales other than HRQOL-physical.Conclusion: This study showed that the quality of life was worse in the adolescent age group, female gender, and the presence of attacks
Anahtar Kelime:

Ailesel Akdeniz Ateşi Olan Çocuk ve Ergenlerde Sağlıkla İlişkili Yaşam Kalitesinin Değerlendirilmesi

Öz:
-
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Adrovic A, Sahin S, Barut K, Kasapcopur O. Familial Mediterranean fever and periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome: shared features and main differences. Rheumatol Int 2019; 39: 29-36. [Crossref]
  • 2. Barut K, Pamuk G, Adrovic A, Sahin S, Kaplan A, Guler M, et al. Comparison of Familial Mediterranean Fever and juvenile idiopathic arthritis patients according to family origin. Turk Arch Pediatr 2018; 53: 31-6. [Crossref]
  • 3. Ozen S, Bilginer Y. A clinical guide to autoinflammatory diseases: familial Mediterranean fever and next-of-kin. Nat Rev Rheumatol 2014; 10: 135-47. [Crossref]
  • 4. Yıldız M, Haşlak F, Adrovic A, Barut K, Kasapçopur Ö. Autoinflammatory Diseases in Childhood. Balkan Med J 2020; 37: 236-46. [Crossref]
  • 5. Samuels J, Ozen S. Familial Mediterranean fever and the other autoinflammatory syndromes: evaluation of the patient with recurrent fever. Curr Opin Rheumatol 2006; 18: 108-17. [Crossref]
  • 6. La Regina M, Ben-Chetrit E, Gasparyan AY, Livneh A, Ozdogan H, Manna R. Current trends in colchicine treatment in familial Mediterranean fever. Clin Exp Rheumatol 2013; 31(3 Suppl 77): 41-6.
  • 7. Çakın Memik N, Ağaoğlu B, Coşkun A, Üneri ÖŞ, Karakaya I. The Validity and Reliability of the Turkish Pediatric Quality of Life Inventory for Children 13-18 Years Old. Türk Psikiyatri Dergisi 2007; 18: 353-63.
  • 8. Eiser C, Morse R. Quality-of-life measures in chronic diseases of childhood. Health Technol Assess 2001; 5: 1-157. [Crossref]
  • 9. Tucker LB. Whose life is it anyway? Understanding quality of life in children with rheumatic diseases. J Rheumatol 2000; 27: 8-11.
  • 10. Haverman L, Grootenhuis MA, van den Berg JM, van Veenendaal M, Dolman KM, Swart JF, et al. Predictors of health-related quality of life in children and adolescents with juvenile idiopathic arthritis: Results from a web-based survey. Arthritis Care Res 2012; 64: 694-703. [Crossref]
  • 11. Petersson C, Simeonsson RJ, Enskar K, Huus K. Comparing children’s self-report instruments for health-related quality of life using the International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY). Health Qual Life Outcomes 2013; 11: 75. [Crossref]
  • 12. McDougall J, Wright V, Schmidt J, Miller L, Lowry K. Applying the ICF framework to study changes in quality-of-life for youth with chronic conditions. Dev Neurorehabil 2011; 14: 41-53. [Crossref]
  • 13. Makay B, Unsal E, Arslan N, Varni JW. Health-related quality of life of school-age children with familial Mediterranean fever. Clin Exp Rheumatol 2009; 27(2 Suppl 53): S96-101.
  • 14. Deger SM, Ozturk MA, Demirag MD, Aslan S, Goker B, Haznedaroglu S, et al. Health-related quality of life and its associations with mood condition in familial Mediterranean fever patients. Rheumatol Int 2011; 31: 623-8. [Crossref]
  • 15. Giese A, Kurucay M, Kilic L, Örnek A, Şendur SN, Lainka E, et al. Quality of life in adult patients with Familial Mediterranean fever living in Germany or Turkey compared to healthy subjects: a study evaluating the effect of disease severity and country of residence. Rheumatol Int 2013; 33: 1713-9. [Crossref]
  • 16. Yalçınkaya F, Özen S, Özçakar ZB, Aktay N, Çakar N, Düzova A, et al. A new set of criteria for the diagnosis of familial Mediterranean fever in childhood. Rheumatology 2009; 48: 395-8. [Crossref]
  • 17. Konukbay D, Gattorno M, Yildiz D, Frenkel J, Acikel C, Sozeri B, et al. A novel assessment tool for clinical care of patients with autoinflammatory disease: juvenile autoinflammatory disease multidimensional assessment report. Clin Exp Rheumatol 2016; 34(6 Suppl 102): 129- 35.
  • 18. Tunca M, Ozdogan H, Kasapcopur O, Yalcinkaya F, Ozen S, Topaloglu R, et al. Familial Mediterranean Fever (FMF) in Turkey. Medicine 2005; 84: 1-11.
  • 19. Ece A, Çakmak E, Uluca Ü, Kelekçi S, Yolbaş İ, Güneş A, et al. The MEFV mutations and their clinical correlations in children with familial Mediterranean fever in southeast Turkey. Rheumatol Int 2014; 34: 207-12. [Crossref]
  • 20. Barut K, Sahin S, Adrovic A, Sinoplu AB, Yucel G, Pamuk G, et al. Familial Mediterranean fever in childhood: a single-center experience. Rheumatol Int 2018; 38: 67- 74. [Crossref]
  • 21. Eiser C. A review of measures of quality of life for children with chronic illness. Arch Dis Child 2001; 84: 205- 11. [Crossref]
  • 22. Matza LS, Swensen AR, Flood EM, Secnik K, Leidy NK. Assessment of Health-Related Quality of Life in Children: A Review of Conceptual, Methodological, and Regulatory Issues. Value Heal 2004; 7: 79-92. [Crossref]
  • 23. Huurre TM, Aro HM. Long-term psychosocial effects of persistent chronic illness. Eur Child Adolesc Psychiatr 2002; 11: 85-91. [Crossref]
  • 24. Costedoat-Chalumeau N, Pouchot J, Guettrot-Imbert G, Le Guern V, Leroux G, Marra D, et al. Adherence to treatment in systemic lupus erythematosus patients. Best Pract Res Clin Rheumatol 2013; 27: 329-40. [Crossref]
APA DURCAN G, BARUT K, HASLAK F, yıldız m, KADAK M, ADROVİC A, ŞAHİN S, Dogangun B, Kasapcopur O (2021). Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever. , 21 - 27.
Chicago DURCAN Gizem,BARUT Kenan,HASLAK Fatih,yıldız mehmet,KADAK M. Tayyib,ADROVİC Amra,ŞAHİN Sezgin,Dogangun Burak,Kasapcopur Ozgur Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever. (2021): 21 - 27.
MLA DURCAN Gizem,BARUT Kenan,HASLAK Fatih,yıldız mehmet,KADAK M. Tayyib,ADROVİC Amra,ŞAHİN Sezgin,Dogangun Burak,Kasapcopur Ozgur Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever. , 2021, ss.21 - 27.
AMA DURCAN G,BARUT K,HASLAK F,yıldız m,KADAK M,ADROVİC A,ŞAHİN S,Dogangun B,Kasapcopur O Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever. . 2021; 21 - 27.
Vancouver DURCAN G,BARUT K,HASLAK F,yıldız m,KADAK M,ADROVİC A,ŞAHİN S,Dogangun B,Kasapcopur O Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever. . 2021; 21 - 27.
IEEE DURCAN G,BARUT K,HASLAK F,yıldız m,KADAK M,ADROVİC A,ŞAHİN S,Dogangun B,Kasapcopur O "Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever." , ss.21 - 27, 2021.
ISNAD DURCAN, Gizem vd. "Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever". (2021), 21-27.
APA DURCAN G, BARUT K, HASLAK F, yıldız m, KADAK M, ADROVİC A, ŞAHİN S, Dogangun B, Kasapcopur O (2021). Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever. Cerrahpaşa Medical Journal, 45(1), 21 - 27.
Chicago DURCAN Gizem,BARUT Kenan,HASLAK Fatih,yıldız mehmet,KADAK M. Tayyib,ADROVİC Amra,ŞAHİN Sezgin,Dogangun Burak,Kasapcopur Ozgur Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever. Cerrahpaşa Medical Journal 45, no.1 (2021): 21 - 27.
MLA DURCAN Gizem,BARUT Kenan,HASLAK Fatih,yıldız mehmet,KADAK M. Tayyib,ADROVİC Amra,ŞAHİN Sezgin,Dogangun Burak,Kasapcopur Ozgur Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever. Cerrahpaşa Medical Journal, vol.45, no.1, 2021, ss.21 - 27.
AMA DURCAN G,BARUT K,HASLAK F,yıldız m,KADAK M,ADROVİC A,ŞAHİN S,Dogangun B,Kasapcopur O Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever. Cerrahpaşa Medical Journal. 2021; 45(1): 21 - 27.
Vancouver DURCAN G,BARUT K,HASLAK F,yıldız m,KADAK M,ADROVİC A,ŞAHİN S,Dogangun B,Kasapcopur O Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever. Cerrahpaşa Medical Journal. 2021; 45(1): 21 - 27.
IEEE DURCAN G,BARUT K,HASLAK F,yıldız m,KADAK M,ADROVİC A,ŞAHİN S,Dogangun B,Kasapcopur O "Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever." Cerrahpaşa Medical Journal, 45, ss.21 - 27, 2021.
ISNAD DURCAN, Gizem vd. "Evaluation of Health-Related Quality of Life in Children and Adolescents with Familial Mediterranean Fever". Cerrahpaşa Medical Journal 45/1 (2021), 21-27.