On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds

Akkurt, Barbaros

doi:10.18596/jotcsa.1000771

On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds

Barbaros AKKURT (İstanbul Teknik Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümü, İstanbul, Türkiye)

Journal of the Turkish Chemical Society, Section A: Chemistry

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Yıl: 2021 Cilt: 8 Sayı: 4 Sayfa Aralığı: 1217 - 1250 Metin Dili: İngilizce DOI: 10.18596/jotcsa.1000771 İndeks Tarihi: 29-07-2022

On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds

Öz:

While studying several pyridazine compounds, the author discovered imidazo[1,2-b]pyridazine(IMP), which is a very versatile compound class. It has been an inhibitor for many enzymes and also it isused as a brominating reagent in organic syntheses. Owing to its high biological activity, researchers havealways considered including this molecule in their final structures. This humble attempt just aims tointroduce this very powerful molecule to the readers, primarily of chemical origin, and should not beconsidered as a full treatise of, especially, the medicinal chemistry of the molecule. This work discusses theinhibitory effects, organic chemistry, applications in material chemistry, and theoretical studies of IMP andrelated molecules. The readers are hereby encouraged to work with medicinal chemists with the newlyprepared molecules including this and similar molecules, in the struggle with many diseases like cancer,Alzheimer’s, and others.

Anahtar Kelime: inhibitors synthesis applications reactions Imidazo[1,2-b]pyridazine, synthesis, inhibitors, applications, reactions

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	Akkurt B (2021). On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds. , 1217 - 1250. 10.18596/jotcsa.1000771
Chicago	Akkurt Barbaros On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds. (2021): 1217 - 1250. 10.18596/jotcsa.1000771
MLA	Akkurt Barbaros On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds. , 2021, ss.1217 - 1250. 10.18596/jotcsa.1000771
AMA	Akkurt B On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds. . 2021; 1217 - 1250. 10.18596/jotcsa.1000771
Vancouver	Akkurt B On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds. . 2021; 1217 - 1250. 10.18596/jotcsa.1000771
IEEE	Akkurt B "On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds." , ss.1217 - 1250, 2021. 10.18596/jotcsa.1000771
ISNAD	Akkurt, Barbaros. "On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds". (2021), 1217-1250. https://doi.org/10.18596/jotcsa.1000771

APA	Akkurt B (2021). On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds. Journal of the Turkish Chemical Society, Section A: Chemistry, 8(4), 1217 - 1250. 10.18596/jotcsa.1000771
Chicago	Akkurt Barbaros On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds. Journal of the Turkish Chemical Society, Section A: Chemistry 8, no.4 (2021): 1217 - 1250. 10.18596/jotcsa.1000771
MLA	Akkurt Barbaros On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds. Journal of the Turkish Chemical Society, Section A: Chemistry, vol.8, no.4, 2021, ss.1217 - 1250. 10.18596/jotcsa.1000771
AMA	Akkurt B On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds. Journal of the Turkish Chemical Society, Section A: Chemistry. 2021; 8(4): 1217 - 1250. 10.18596/jotcsa.1000771
Vancouver	Akkurt B On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds. Journal of the Turkish Chemical Society, Section A: Chemistry. 2021; 8(4): 1217 - 1250. 10.18596/jotcsa.1000771
IEEE	Akkurt B "On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds." Journal of the Turkish Chemical Society, Section A: Chemistry, 8, ss.1217 - 1250, 2021. 10.18596/jotcsa.1000771
ISNAD	Akkurt, Barbaros. "On the Biological Importance, Preparation, and Uses of Imidazo[1,2- b]pyridazine-Based Compounds". Journal of the Turkish Chemical Society, Section A: Chemistry 8/4 (2021), 1217-1250. https://doi.org/10.18596/jotcsa.1000771