Yıl: 2021 Cilt: 11 Sayı: 2 Sayfa Aralığı: 174 - 178 Metin Dili: İngilizce DOI: 10.4274/jarem.galenos.2021.69885 İndeks Tarihi: 22-11-2021

Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques

Öz:
Objective: To investigate reproductive outcomes of patients with infertility due to severe vaginismus undergoing in vitro fertilisation and embryo transfer (IVF-ET). Methods: Twenty-nine patients were selected among patients who presented with complaints of vaginismus-related infertility. The diagnosis and severity of vaginismus were assessed according to the Lamont-Pacik system. Five women with milder forms of vaginismus were treated with other options. Of the remaining 24 patients with severe vaginismus, 20 had Lamont grade 3 and four with Lamont grade 4. Likewise, 24 patients who were diagnosed with unexplained infertility were selected as the control group. Results: Of the 24 patients, 15 had first attempt, 8 had second and 1 had fourth attempt. Folliculometry was performed with abdominal ultrasonography in 21 women with normal body mass index. Folliculometry and endometrial evaluation were performed in three overweight cases with transvaginal ultrasonography under sedation. Single ET was performed in 27 cycles, and two ETs were performed in the others. Beta human chorionic gonadotropin positivity was detected in 20 of the 39 cycles. Similarly, in 20 patients, while clinical pregnancy was detected (20 of 39 cycles, 51.2%), the number of cycles with term and live births were 16 (16 of 39 cycles, 41.0%). While clinical pregnancy was detected in 25 of 35 cycles in the control group (71.4%), live birth was achieved in 22 cycles (62.8%). Compared with the vaginismus group, clinical pregnancy rate (20 vs 25, p<0.09) and live birth rate (LBR) (16 vs 22, p<0.06) were comparable. Conclusion: Both clinical pregnancy and LBRs of women with infertility due to severe vaginismus undergoing IVF-ET are similar to women with unexplained infertility.
Anahtar Kelime:

Vajinismuslu İnfertil Kadınların Yardımcı Üreme Teknikleriyle Yönetimi

Öz:
Amaç: Şiddetli vajinismus tanısı almış infertil olguların in vitro fertilizasyon ve embriyo transferi (IVF-ET) sonuçlarını sağlıklı infertil kontrollerle karşılaştırmaktır. Yöntemler: Vajinismusa bağlı kısırlık şikayeti ile başvuran hastalar arasından 29 hasta seçildi. Vajinismus tanısı ve şiddeti Lamont-Pacik sistemine göre konuldu. Hafif vajinismus formlarına sahip 5 kadın başka yöntemlerle tedavi edildi. Çalışmaya dahil edilen ve şiddetli vajinismus tanısı alan toplam 24 olgunun 20 tanesi Lamont grade 3 ve geriye kalan 4 olgu ise Lamont grade 4 idi. Açıklanamayan infertilite tanısı alan 24 hasta kontrol grubu olarak seçildi. Bulgular: Yirmi dört hastanın 15’i ilk IVF-ET denemesinde, 8 hasta ikinci ve bir hasta da 4. denemesinde idi. Vücut kitle indeksi (VKİ) normal olan 21 vajinismuslu kadına abdominal ultrasonografi ile folikülometri yapıldı. VKİ yüksek olan 3 olguda ise sedasyon altında transvajinal ultrasonografi ile hem folikülometri hem de endometriyal değerlendirme yapıldı. Yirmi yedi siklusta tek ET, 8 siklusta ise iki ET gerçekleştirildi. Otuz dokuz siklusun 20’sinde beta human karyonik gonodotropin pozitifliği tespit edildi. Benzer şekilde 20 olguda klinik gebelik tespit edilirken (%51,2) term ve canlı doğum ile sonuçlanan siklus sayısı 16 idi (%41). Kontrol grubundaki olgularda 35 siklusun 25’inde klinik gebelik oranı (CPR) saptanırken (%71,4) 22 siklusta canlı doğum oranı (CDO) sağlandı (%62,8). Vajinismus grubu ile karşılaştırıldığı zaman CPR (20 vs 25, p<0,09) ve LBR oranları benzer olarak bulundu (16 vs 22, p<0,06). Sonuç: IVF-ET uygulanan şiddetli vajinismuslu infertil kadınların hem klinik gebelik hem de CDO’ları, açıklanamayan infertiliteye sahip kadınlarla benzerdir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA yurci a, Karayağız S (2021). Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques. , 174 - 178. 10.4274/jarem.galenos.2021.69885
Chicago yurci arzu,Karayağız Saban Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques. (2021): 174 - 178. 10.4274/jarem.galenos.2021.69885
MLA yurci arzu,Karayağız Saban Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques. , 2021, ss.174 - 178. 10.4274/jarem.galenos.2021.69885
AMA yurci a,Karayağız S Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques. . 2021; 174 - 178. 10.4274/jarem.galenos.2021.69885
Vancouver yurci a,Karayağız S Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques. . 2021; 174 - 178. 10.4274/jarem.galenos.2021.69885
IEEE yurci a,Karayağız S "Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques." , ss.174 - 178, 2021. 10.4274/jarem.galenos.2021.69885
ISNAD yurci, arzu - Karayağız, Saban. "Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques". (2021), 174-178. https://doi.org/10.4274/jarem.galenos.2021.69885
APA yurci a, Karayağız S (2021). Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques. JAREM, 11(2), 174 - 178. 10.4274/jarem.galenos.2021.69885
Chicago yurci arzu,Karayağız Saban Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques. JAREM 11, no.2 (2021): 174 - 178. 10.4274/jarem.galenos.2021.69885
MLA yurci arzu,Karayağız Saban Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques. JAREM, vol.11, no.2, 2021, ss.174 - 178. 10.4274/jarem.galenos.2021.69885
AMA yurci a,Karayağız S Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques. JAREM. 2021; 11(2): 174 - 178. 10.4274/jarem.galenos.2021.69885
Vancouver yurci a,Karayağız S Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques. JAREM. 2021; 11(2): 174 - 178. 10.4274/jarem.galenos.2021.69885
IEEE yurci a,Karayağız S "Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques." JAREM, 11, ss.174 - 178, 2021. 10.4274/jarem.galenos.2021.69885
ISNAD yurci, arzu - Karayağız, Saban. "Management of Women with Vaginismus-related Infertility Through Assisted Reproductive Techniques". JAREM 11/2 (2021), 174-178. https://doi.org/10.4274/jarem.galenos.2021.69885