The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis

Bilen, Handan; Elmas, Ömer Faruk; Metin, Mahmut Sami; Akdeniz, Necmettin

doi:10.3906/sag-2106-81

The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis

Mahmut Sami METİN, (Kırşehir Ahi Evran Üniversitesi, Tıp Fakültesi, Dermatoloji Anabilim Dalı, Kırşehir, Türkiye)

Handan BİLEN, (Atatürk Üniversitesi, Tıp Fakültesi, Dermatoloji Anabilim Dalı, Erzurum, Türkiye)

Ömer Faruk ELMAS, (Kırıkkale Üniversitesi, Tıp Fakültesi, Dermatoloji Anabilim Dalı, Kırıkkale, Türkiye)

Necmettin AKDENİZ (Memorial Ataşehir Hastanesi, Dermatoloji Bölümü, İstanbul, Türkiye)

Turkish Journal of Medical Sciences

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Yıl: 2021 Cilt: 51 Sayı: 6 Sayfa Aralığı: 3017 - 3021 Metin Dili: İngilizce DOI: 10.3906/sag-2106-81 İndeks Tarihi: 05-01-2022

The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis

Öz:

Background/aim: Human HIV-1 TAT interactive protein 2 (HTATIP2/TIP30) is a gene that is extensively expressed in human tissues as well as in tumor tissues. This study aimed to explore the potential role of HTATIP2/TIP30 in contact dermatitis (CD), which is one of the most common inflammatory cutaneous conditions. Materials and methods: This cross-sectional study involved adult patients with acute contact dermatitis who were admitted to the outpatient dermatology clinic of a tertiary hospital and healthy adult volunteers without any cutaneous or systemic diseases. The blood concentration of HTATIP2/TIP30 was measured using ELISA kits. Results: The research sample consisted of 31 patients with CD (18 males, 13 females) and 20 healthy control subjects (14 males, 6 females). The mean ages of the patients with CD and healthy volunteers were 37 and 30 years, respectively (p > 0.05). The mean value of serum HTATIP2/TIP30 levels in patients with CD was 1.65 ng ml–1, which is 0.60 ng ml–1 in the control group (p = 0.02) Conclusion: In this study, serum levels of HTATIP2/TIP30 were statistically significantly higher in patients with CD when compared to healthy controls. This outcome may indicate possible role of HTATIP2/TIP30 in the pathogenesis of CD.Key words: Contact dermatitis, CC3/TIP30, HTATIP2/TIP30

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Metin M, Bilen H, Elmas Ö, Akdeniz N (2021). The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis. , 3017 - 3021. 10.3906/sag-2106-81
Chicago	Metin Mahmut Sami,Bilen Handan,Elmas Ömer Faruk,Akdeniz Necmettin The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis. (2021): 3017 - 3021. 10.3906/sag-2106-81
MLA	Metin Mahmut Sami,Bilen Handan,Elmas Ömer Faruk,Akdeniz Necmettin The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis. , 2021, ss.3017 - 3021. 10.3906/sag-2106-81
AMA	Metin M,Bilen H,Elmas Ö,Akdeniz N The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis. . 2021; 3017 - 3021. 10.3906/sag-2106-81
Vancouver	Metin M,Bilen H,Elmas Ö,Akdeniz N The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis. . 2021; 3017 - 3021. 10.3906/sag-2106-81
IEEE	Metin M,Bilen H,Elmas Ö,Akdeniz N "The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis." , ss.3017 - 3021, 2021. 10.3906/sag-2106-81
ISNAD	Metin, Mahmut Sami vd. "The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis". (2021), 3017-3021. https://doi.org/10.3906/sag-2106-81

APA	Metin M, Bilen H, Elmas Ö, Akdeniz N (2021). The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis. Turkish Journal of Medical Sciences, 51(6), 3017 - 3021. 10.3906/sag-2106-81
Chicago	Metin Mahmut Sami,Bilen Handan,Elmas Ömer Faruk,Akdeniz Necmettin The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis. Turkish Journal of Medical Sciences 51, no.6 (2021): 3017 - 3021. 10.3906/sag-2106-81
MLA	Metin Mahmut Sami,Bilen Handan,Elmas Ömer Faruk,Akdeniz Necmettin The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis. Turkish Journal of Medical Sciences, vol.51, no.6, 2021, ss.3017 - 3021. 10.3906/sag-2106-81
AMA	Metin M,Bilen H,Elmas Ö,Akdeniz N The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis. Turkish Journal of Medical Sciences. 2021; 51(6): 3017 - 3021. 10.3906/sag-2106-81
Vancouver	Metin M,Bilen H,Elmas Ö,Akdeniz N The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis. Turkish Journal of Medical Sciences. 2021; 51(6): 3017 - 3021. 10.3906/sag-2106-81
IEEE	Metin M,Bilen H,Elmas Ö,Akdeniz N "The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis." Turkish Journal of Medical Sciences, 51, ss.3017 - 3021, 2021. 10.3906/sag-2106-81
ISNAD	Metin, Mahmut Sami vd. "The potential role of human HIV-1 TAT-Interactive Protein 2 levels in the pathogenesis of contact dermatitis". Turkish Journal of Medical Sciences 51/6 (2021), 3017-3021. https://doi.org/10.3906/sag-2106-81