Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results

sahin, mustafa; Önal, Binnur; Ucan, Bekir; Sencar, Muhammed Erkam; özbek, mustafa; cakal, erman; Kizilgul, Muhammed; Düğer, Hakan

doi:10.3906/sag-2101-246

Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results

Bekir UÇAN, (Sağlık Bilimleri Üniversitesi, Ankara Dışkapı Eğitim ve Araştırma Hastanesi, Endokrinoloji ve Metabolizma Bilim Dalı, Ankara Türkiye)

Mustafa ŞAHİN, (Ankara Üniversitesi, Tıp Fakültesi, Endokrinoloji ve Metabolizma Anabilim Dalı, Ankara, Türkiye)

Binnur ÖNAL, (Sağlık Bilimleri Üniversitesi, Ankara Dışkapı Eğitim ve Araştırma Hastanesi, Endokrinoloji ve Metabolizma Bilim Dalı, Ankara Türkiye)

Muhammed KIZILGÜL, (Sağlık Bilimleri Üniversitesi, Ankara Dışkapı Eğitim ve Araştırma Hastanesi, Endokrinoloji ve Metabolizma Bilim Dalı, Ankara Türkiye)

Hakan DÜĞER, (Sağlık Bilimleri Üniversitesi, Ankara Dışkapı Eğitim ve Araştırma Hastanesi, Endokrinoloji ve Metabolizma Bilim Dalı, Ankara Türkiye)

Muhammed Erkam SENCAR, (Sağlık Bilimleri Üniversitesi, Ankara Dışkapı Eğitim ve Araştırma Hastanesi, Endokrinoloji ve Metabolizma Bilim Dalı, Ankara, Türkiye)

Erman ÇAKAL, (Sağlık Bilimleri Üniversitesi, Ankara Dışkapı Eğitim ve Araştırma Hastanesi, Endokrinoloji ve Metabolizma Bilim Dalı, Ankara, Türkiye)

Mustafa ÖZBEK (Sağlık Bilimleri Üniversitesi, Ankara Dışkapı Eğitim ve Araştırma Hastanesi, Endokrinoloji ve Metabolizma Bilim Dalı, Ankara, Türkiye)

Turkish Journal of Medical Sciences

1 0

Yıl: 2021 Cilt: 51 Sayı: 6 Sayfa Aralığı: 2924 - 2930 Metin Dili: İngilizce DOI: 10.3906/sag-2101-246 İndeks Tarihi: 05-01-2022

Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results

Öz:

Background/aim: The management of nodules with indeterminate cytology [atypia of undetermined significance (AUS), follicular lesion of undetermined significance (FLUS), follicular neoplasm (FN), suspicious for a follicular neoplasm (SFN), and suspicious for malignancy (SM)] results is controversial. To assess the role of the elastography technique in the diagnosis of malignancy in the subtypes of indeterminate thyroid nodules. Materials and methods: We included 132 patients with indeterminate cytology who underwent thyroid surgery. Sensitivity, specificity, area under the curve, and optimal cut-off points were calculated with receiver operating characteristic (ROC) analysis for elastography score (ES) and strain index (SI). Results: Malignancy was observed in 27/95 (28.4%) of the AUS-FLUS cytology and 12/24 (50%) of FN, SFN cytology. All of the 13 patients (100 %) with SM are found to be malignant on histology. In the FLUS group, nodules with ES greater or equal to 3, the presence of malignancy was higher 17/41 (41.5%) when compared with nodules with ES smaller than 39/46 (19.6 %) (p = 0.023). In the SFN group, 2 of 2 nodules with an ES score of 4 and 1 of 1 nodule with an ES score of 5 were malignant. In the FLUS group, 4 of 10 nodules with an ES score of 4 and 2 of 2 nodules with an ES score of 5 were malignant. Conclusion: Thyroid elastography may reduce unnecessary surgery for both patients with AUS/FLUS and selected SFN cytology. Elastography appears to be helpful in follicular variants and other types of papillary thyroid cancer, however, not in follicular thyroid cancer.Key words: Elastography, indeterminate cytology, malignancy, thyroid

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Ucan B, sahin m, Önal B, Kizilgul M, Düğer H, Sencar M, cakal e, özbek m (2021). Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results. , 2924 - 2930. 10.3906/sag-2101-246
Chicago	Ucan Bekir,sahin mustafa,Önal Binnur,Kizilgul Muhammed,Düğer Hakan,Sencar Muhammed Erkam,cakal erman,özbek mustafa Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results. (2021): 2924 - 2930. 10.3906/sag-2101-246
MLA	Ucan Bekir,sahin mustafa,Önal Binnur,Kizilgul Muhammed,Düğer Hakan,Sencar Muhammed Erkam,cakal erman,özbek mustafa Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results. , 2021, ss.2924 - 2930. 10.3906/sag-2101-246
AMA	Ucan B,sahin m,Önal B,Kizilgul M,Düğer H,Sencar M,cakal e,özbek m Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results. . 2021; 2924 - 2930. 10.3906/sag-2101-246
Vancouver	Ucan B,sahin m,Önal B,Kizilgul M,Düğer H,Sencar M,cakal e,özbek m Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results. . 2021; 2924 - 2930. 10.3906/sag-2101-246
IEEE	Ucan B,sahin m,Önal B,Kizilgul M,Düğer H,Sencar M,cakal e,özbek m "Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results." , ss.2924 - 2930, 2021. 10.3906/sag-2101-246
ISNAD	Ucan, Bekir vd. "Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results". (2021), 2924-2930. https://doi.org/10.3906/sag-2101-246

APA	Ucan B, sahin m, Önal B, Kizilgul M, Düğer H, Sencar M, cakal e, özbek m (2021). Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results. Turkish Journal of Medical Sciences, 51(6), 2924 - 2930. 10.3906/sag-2101-246
Chicago	Ucan Bekir,sahin mustafa,Önal Binnur,Kizilgul Muhammed,Düğer Hakan,Sencar Muhammed Erkam,cakal erman,özbek mustafa Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results. Turkish Journal of Medical Sciences 51, no.6 (2021): 2924 - 2930. 10.3906/sag-2101-246
MLA	Ucan Bekir,sahin mustafa,Önal Binnur,Kizilgul Muhammed,Düğer Hakan,Sencar Muhammed Erkam,cakal erman,özbek mustafa Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results. Turkish Journal of Medical Sciences, vol.51, no.6, 2021, ss.2924 - 2930. 10.3906/sag-2101-246
AMA	Ucan B,sahin m,Önal B,Kizilgul M,Düğer H,Sencar M,cakal e,özbek m Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results. Turkish Journal of Medical Sciences. 2021; 51(6): 2924 - 2930. 10.3906/sag-2101-246
Vancouver	Ucan B,sahin m,Önal B,Kizilgul M,Düğer H,Sencar M,cakal e,özbek m Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results. Turkish Journal of Medical Sciences. 2021; 51(6): 2924 - 2930. 10.3906/sag-2101-246
IEEE	Ucan B,sahin m,Önal B,Kizilgul M,Düğer H,Sencar M,cakal e,özbek m "Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results." Turkish Journal of Medical Sciences, 51, ss.2924 - 2930, 2021. 10.3906/sag-2101-246
ISNAD	Ucan, Bekir vd. "Assessment of diagnostic value of preoperative elastography in thyroid nodules having indeterminate cytology results". Turkish Journal of Medical Sciences 51/6 (2021), 2924-2930. https://doi.org/10.3906/sag-2101-246