The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients
Yıl: 2021 Cilt: 51 Sayı: 4 Sayfa Aralığı: 1647 - 1652 Metin Dili: İngilizce DOI: 10.3906/sag-2103-72 İndeks Tarihi: 11-01-2022
The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients
Öz: Background/aim: The disease caused by SARS-CoV-2 was named as COVID-19. There is as yet insufficient information about the effects of HSCT on the clinical course of COVID-19. In the present study, we aimed to investigate the clinical course of COVID-19 in patients who had undergone HSCT. Materials and methods: We analyzed baseline characteristics, clinical course and findings of COVID-19, hospitalization and death rates, overall survival, and case fatality rates of HSCT recipients diagnosed with COVID-19 retrospectively. Results: 57.6% of the patients underwent AHSCT, and 42.4% underwent allo-HSCT. 60.6%, 27.3%, and 12.1% of the patients had mild, moderate, and severe COVID-19 or critical illness, respectively. Overall, 45.5% were hospitalized, 12.1% required intensive care, and 9.1% necessitated invasive mechanical ventilation. The total CFR was 9.1% in HSCT recipients, 22.2% in patients with active hematologic malignancy, and 4.2% in patients without active hematologic malignancy. Conclusion: It can be concluded that mortality of HSCT recipients is lower in patients whose primary disease is in remission compared to ones that are not in remission. Further studies with larger group patients are needed in order to delineate the effects of COVID-19 on HSCT patients.Key words: Hematopoietic stem cell transplantation, bone marrow transplant, COVID-19
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA | Karatas A, Malkan U, Velet M, Demiroglu H, Büyükaşık Y, Telli Dizman G, Inkaya A, erdoğdu b, Çınar O, Aladag E, AKSU S, Haznedaroglu I, Özcebe O, Sayinalp N, Göker H (2021). The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients. , 1647 - 1652. 10.3906/sag-2103-72 |
Chicago | Karatas Ayse,Malkan Umit Yavuz,Velet Mustafa,Demiroglu Haluk,Büyükaşık Yahya,Telli Dizman Gulcin,Inkaya Ahmet Cagkan,erdoğdu batuhan,Çınar Olgu Erkin,Aladag Elifcan,AKSU SALIH,Haznedaroglu Ibrahim C.,Özcebe Osman,Sayinalp Nilgun,Göker Hakan The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients. (2021): 1647 - 1652. 10.3906/sag-2103-72 |
MLA | Karatas Ayse,Malkan Umit Yavuz,Velet Mustafa,Demiroglu Haluk,Büyükaşık Yahya,Telli Dizman Gulcin,Inkaya Ahmet Cagkan,erdoğdu batuhan,Çınar Olgu Erkin,Aladag Elifcan,AKSU SALIH,Haznedaroglu Ibrahim C.,Özcebe Osman,Sayinalp Nilgun,Göker Hakan The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients. , 2021, ss.1647 - 1652. 10.3906/sag-2103-72 |
AMA | Karatas A,Malkan U,Velet M,Demiroglu H,Büyükaşık Y,Telli Dizman G,Inkaya A,erdoğdu b,Çınar O,Aladag E,AKSU S,Haznedaroglu I,Özcebe O,Sayinalp N,Göker H The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients. . 2021; 1647 - 1652. 10.3906/sag-2103-72 |
Vancouver | Karatas A,Malkan U,Velet M,Demiroglu H,Büyükaşık Y,Telli Dizman G,Inkaya A,erdoğdu b,Çınar O,Aladag E,AKSU S,Haznedaroglu I,Özcebe O,Sayinalp N,Göker H The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients. . 2021; 1647 - 1652. 10.3906/sag-2103-72 |
IEEE | Karatas A,Malkan U,Velet M,Demiroglu H,Büyükaşık Y,Telli Dizman G,Inkaya A,erdoğdu b,Çınar O,Aladag E,AKSU S,Haznedaroglu I,Özcebe O,Sayinalp N,Göker H "The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients." , ss.1647 - 1652, 2021. 10.3906/sag-2103-72 |
ISNAD | Karatas, Ayse vd. "The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients". (2021), 1647-1652. https://doi.org/10.3906/sag-2103-72 |
APA | Karatas A, Malkan U, Velet M, Demiroglu H, Büyükaşık Y, Telli Dizman G, Inkaya A, erdoğdu b, Çınar O, Aladag E, AKSU S, Haznedaroglu I, Özcebe O, Sayinalp N, Göker H (2021). The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients. Turkish Journal of Medical Sciences, 51(4), 1647 - 1652. 10.3906/sag-2103-72 |
Chicago | Karatas Ayse,Malkan Umit Yavuz,Velet Mustafa,Demiroglu Haluk,Büyükaşık Yahya,Telli Dizman Gulcin,Inkaya Ahmet Cagkan,erdoğdu batuhan,Çınar Olgu Erkin,Aladag Elifcan,AKSU SALIH,Haznedaroglu Ibrahim C.,Özcebe Osman,Sayinalp Nilgun,Göker Hakan The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients. Turkish Journal of Medical Sciences 51, no.4 (2021): 1647 - 1652. 10.3906/sag-2103-72 |
MLA | Karatas Ayse,Malkan Umit Yavuz,Velet Mustafa,Demiroglu Haluk,Büyükaşık Yahya,Telli Dizman Gulcin,Inkaya Ahmet Cagkan,erdoğdu batuhan,Çınar Olgu Erkin,Aladag Elifcan,AKSU SALIH,Haznedaroglu Ibrahim C.,Özcebe Osman,Sayinalp Nilgun,Göker Hakan The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients. Turkish Journal of Medical Sciences, vol.51, no.4, 2021, ss.1647 - 1652. 10.3906/sag-2103-72 |
AMA | Karatas A,Malkan U,Velet M,Demiroglu H,Büyükaşık Y,Telli Dizman G,Inkaya A,erdoğdu b,Çınar O,Aladag E,AKSU S,Haznedaroglu I,Özcebe O,Sayinalp N,Göker H The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients. Turkish Journal of Medical Sciences. 2021; 51(4): 1647 - 1652. 10.3906/sag-2103-72 |
Vancouver | Karatas A,Malkan U,Velet M,Demiroglu H,Büyükaşık Y,Telli Dizman G,Inkaya A,erdoğdu b,Çınar O,Aladag E,AKSU S,Haznedaroglu I,Özcebe O,Sayinalp N,Göker H The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients. Turkish Journal of Medical Sciences. 2021; 51(4): 1647 - 1652. 10.3906/sag-2103-72 |
IEEE | Karatas A,Malkan U,Velet M,Demiroglu H,Büyükaşık Y,Telli Dizman G,Inkaya A,erdoğdu b,Çınar O,Aladag E,AKSU S,Haznedaroglu I,Özcebe O,Sayinalp N,Göker H "The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients." Turkish Journal of Medical Sciences, 51, ss.1647 - 1652, 2021. 10.3906/sag-2103-72 |
ISNAD | Karatas, Ayse vd. "The clinical course of COVID-19 in hematopoietic stem cell transplantation (HSCT) recipients". Turkish Journal of Medical Sciences 51/4 (2021), 1647-1652. https://doi.org/10.3906/sag-2103-72 |