Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?

TOLUNAY, HARUN EGEMEN; sarsmaz, kemal; şahin, Dilek; Yucel, Aykan; Orgul, Gokcen; Eroglu, Hasan

doi:10.21613/GORM.2020.1064

Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?

Hasan EROĞLU, (Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Türkiye)

Harun Egemen TOLUNAY, (Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Türkiye)

Kemal SARSMAZ, (Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Türkiye)

Gökçen ÖRGÜL, (Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Türkiye)

Dilek ŞAHIN, (Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Türkiye)

Aykan YÜCEL (Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Türkiye)

GORM:Gynecology Obstetrics & Reproductive Medicine

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Yıl: 2021 Cilt: 27 Sayı: 2 Sayfa Aralığı: 105 - 108 Metin Dili: İngilizce DOI: 10.21613/GORM.2020.1064 İndeks Tarihi: 04-02-2022

Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?

Öz:

OBJECTIVES: We aimed to determine whether mean platelet volume value and/or neutrophil/lymphocyte ratio values are useful as a predictive marker for gestational cholestasis. STUDY DESIGN: Retrospective analysis of the data of patients diagnosed with pregnancy cholestasis between 2018-2019 in a perinatology clinic. 352 pregnant women were enrolled in the study (122 pregnant women with Intrahepatic cholestasis as study group and 230 pregnant women with no morbidity as the control group) RESULTS: Mean platelet volume was significantly higher in pregnant women with intrahepatic cholestasis compared to the healthy controls, 9.30 (7-18) and 8.6 (6.7-11.5), respectively. The neutrophil/lymphocyte ratio was significantly higher in pregnant women with intrahepatic cholestasis compared to the healthy controls, 3.93 (0.46-13.75) and 4.25 (0.87-17.1), respectively. There was a statistically significant difference between the two groups for mean platelet volume (p <0.001). In the roc analysis, 8.85 fL for mean platelet volume had a sensitivity of 65% and a specificity of 59%. CONCLUSION: When compared with healthy pregnancies, mean platelet volume value in gestational cholestasis increases significantly. However, the predictive strength of mean platelet volume for cholestasis is not strong enough to recommend its usage as a single parameter in clinical practice.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Eroglu H, TOLUNAY H, sarsmaz k, Orgul G, şahin D, Yucel A (2021). Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?. , 105 - 108. 10.21613/GORM.2020.1064
Chicago	Eroglu Hasan,TOLUNAY HARUN EGEMEN,sarsmaz kemal,Orgul Gokcen,şahin Dilek,Yucel Aykan Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?. (2021): 105 - 108. 10.21613/GORM.2020.1064
MLA	Eroglu Hasan,TOLUNAY HARUN EGEMEN,sarsmaz kemal,Orgul Gokcen,şahin Dilek,Yucel Aykan Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?. , 2021, ss.105 - 108. 10.21613/GORM.2020.1064
AMA	Eroglu H,TOLUNAY H,sarsmaz k,Orgul G,şahin D,Yucel A Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?. . 2021; 105 - 108. 10.21613/GORM.2020.1064
Vancouver	Eroglu H,TOLUNAY H,sarsmaz k,Orgul G,şahin D,Yucel A Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?. . 2021; 105 - 108. 10.21613/GORM.2020.1064
IEEE	Eroglu H,TOLUNAY H,sarsmaz k,Orgul G,şahin D,Yucel A "Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?." , ss.105 - 108, 2021. 10.21613/GORM.2020.1064
ISNAD	Eroglu, Hasan vd. "Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?". (2021), 105-108. https://doi.org/10.21613/GORM.2020.1064

APA	Eroglu H, TOLUNAY H, sarsmaz k, Orgul G, şahin D, Yucel A (2021). Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?. GORM:Gynecology Obstetrics & Reproductive Medicine, 27(2), 105 - 108. 10.21613/GORM.2020.1064
Chicago	Eroglu Hasan,TOLUNAY HARUN EGEMEN,sarsmaz kemal,Orgul Gokcen,şahin Dilek,Yucel Aykan Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?. GORM:Gynecology Obstetrics & Reproductive Medicine 27, no.2 (2021): 105 - 108. 10.21613/GORM.2020.1064
MLA	Eroglu Hasan,TOLUNAY HARUN EGEMEN,sarsmaz kemal,Orgul Gokcen,şahin Dilek,Yucel Aykan Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?. GORM:Gynecology Obstetrics & Reproductive Medicine, vol.27, no.2, 2021, ss.105 - 108. 10.21613/GORM.2020.1064
AMA	Eroglu H,TOLUNAY H,sarsmaz k,Orgul G,şahin D,Yucel A Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?. GORM:Gynecology Obstetrics & Reproductive Medicine. 2021; 27(2): 105 - 108. 10.21613/GORM.2020.1064
Vancouver	Eroglu H,TOLUNAY H,sarsmaz k,Orgul G,şahin D,Yucel A Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?. GORM:Gynecology Obstetrics & Reproductive Medicine. 2021; 27(2): 105 - 108. 10.21613/GORM.2020.1064
IEEE	Eroglu H,TOLUNAY H,sarsmaz k,Orgul G,şahin D,Yucel A "Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?." GORM:Gynecology Obstetrics & Reproductive Medicine, 27, ss.105 - 108, 2021. 10.21613/GORM.2020.1064
ISNAD	Eroglu, Hasan vd. "Are the Mean Platelet Volume and Neutrophil/Lymphocyte Ratio Predictive for Gestational Cholestasis?". GORM:Gynecology Obstetrics & Reproductive Medicine 27/2 (2021), 105-108. https://doi.org/10.21613/GORM.2020.1064