Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?

YORMAZ, BURCU; Tulek, Baykal; Cizmecioglu, Ahmet; ahmadlı, nijat; Göktepe, Mevlüt Hakan; Ergün, Dilek; Akay Çizmecioğlu, Hilal; KANAT, FIKRET

Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?

AHMET ÇİZMECİOĞLU, (1Selcuk University, Faculty of Medicine, Department of Internal Medicine, Konya)

Burcu Yormaz, (2Selcuk University, Faculty of Medicine, Department of Chest Diseases, Konya)

Hilal Akay Cizmecioglu, (3Necmettin Erbakan University, Meram Faculty of Medicine, Department of Internal Medicine, Konya, Turkey)

Mevlüt Hakan GÖKTEPE, (3Necmettin Erbakan University, Meram Faculty of Medicine, Department of Internal Medicine, Konya)

Nijat Ahmadli, (Selcuk University, Faculty of Medicine, Department of Internal Medicine, Konya)

Dilek ERGÜN, (2Selcuk University, Faculty of Medicine, Department of Chest Diseases, Konya)

Baykal TÜLEK, (2Selcuk University, Faculty of Medicine, Department of Chest Diseases, Konya,)

Fikret Kanat (Selcuk University, Faculty of Medicine, Department of Chest Diseases, Konya)

Selçuk Tıp Dergisi

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Yıl: 2021 Cilt: 37 Sayı: 3 Sayfa Aralığı: 224 - 230 Metin Dili: İngilizce İndeks Tarihi: 07-02-2022

Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?

Öz:

Aim: Hypoxemia is a vital criterion used to determine prognosis in coronavirus disease (COVID-19) cases. This study thus examined the effectiveness of capillary refill time (CRT) in defining hypoxiadependent disease severity in COVID-19 patients. Patients and Methods: This prospective study was conducted with COVID-19 patients and an agematched healthy group. The optimum test ambiance was provided, and a stable smartphone platform was used to record the measurements (in ms) to standardize our method. The captured videos were then evaluated using a video processing program. Results: In total, 39 patients with COVID-19 and 40 control groups participated in this study. The patients were further divided into the moderate (n = 25) or severe group (n = 14) according to disease severity. The mean oxygen saturation of both moderate/severe groups was above 94%. Per disease severity, the CRT measurements were higher in the severe group than in the moderate group (p = 0.009). In patients without lymphopenia (n = 18), CRT values were found to be increased in the severe group (p = 0.008). The use of CRT in patients with Covid-19 was practicable (AUC: 0.91; 95% CI 0.848-0.978; P = 0.001). Conclusions: Our results show that CRT prolongation can occur in patients with COVID-19. In patients without lymphopenia and with normal O2 levels, detecting CRT prolongation may be a criterion for early admission to ICU.

Anahtar Kelime:

Kapiller Dolum Süresi, COVID-19 Hastalarında Erken Prognostik Faktör mü?

Öz:

Amaç: Hipoksemi, koronavirüs hastalığında (COVID-19) prognozu belirlemek için kullanılan hayati bir kriterdir. Bu çalışmada, COVID-19 hastalarında hipoksiye bağlı hastalık şiddetini tanımlamada kapiller dolum zamanının (KDZ) etkinliği değerlendirilmiştir . Hastalar ve Yöntem: Bu prospektif çalışma, COVID-19 hastaları ve yaşça eşleştirilmiş bir sağlıklı grubu ile gerçekleştirilmiştir. Ölçüm için optimum test ortamı sağlandı ve yöntemimizi standartlaştırmak ve ölçümleri (milisaniye cinsinden) kaydetmek için sabit bir akıllı telefon platformu kullanıldı. Kaydedilen videolar daha sonra bir video işleme programı kullanılarak değe rlendirildi. Bulgular: Çalışmaya toplamda 39 COVID-19 hastası ve 40 kontrol grubu katıldı. Hastalar hastalık şiddetlerine göre orta (n= 25) veya ağır (n= 14) gruplara ayrıldı. Her iki orta / şiddetli grubun ortalama oksijen satürasyonu %94'ün üzerindeydi. Hastalık şiddetine göre KDZ ölçümleri şiddetli grupta orta gruba göre daha yüksekti (p= 0.009). Lenfopeni olmayan hastalarda (n= 18), KDZ değerlerinin şiddetli grupta arttığı saptandı (p= 0.008). Covid-19’lu hastaların takibinde KDZ kullanımı uygulanabilirdi (AUC: 0.91; %95 SH 0.848-0.978; P= 0.001) Sonuç: Sonuçlarımız, COVID-19’lu hastalarda KDZ süresinin uzayabileceğini göstermektedir. Lenfopenisi olmayan ve O2 seviyesi normal olan hastalarda, KDZ uzamasının saptanması yoğun bakıma erken kabul için bir kriter olabilir .

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Cizmecioglu A, YORMAZ B, Akay Çizmecioğlu H, Göktepe M, ahmadlı n, Ergün D, Tulek B, KANAT F (2021). Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?. , 224 - 230.
Chicago	Cizmecioglu Ahmet,YORMAZ BURCU,Akay Çizmecioğlu Hilal,Göktepe Mevlüt Hakan,ahmadlı nijat,Ergün Dilek,Tulek Baykal,KANAT FIKRET Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?. (2021): 224 - 230.
MLA	Cizmecioglu Ahmet,YORMAZ BURCU,Akay Çizmecioğlu Hilal,Göktepe Mevlüt Hakan,ahmadlı nijat,Ergün Dilek,Tulek Baykal,KANAT FIKRET Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?. , 2021, ss.224 - 230.
AMA	Cizmecioglu A,YORMAZ B,Akay Çizmecioğlu H,Göktepe M,ahmadlı n,Ergün D,Tulek B,KANAT F Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?. . 2021; 224 - 230.
Vancouver	Cizmecioglu A,YORMAZ B,Akay Çizmecioğlu H,Göktepe M,ahmadlı n,Ergün D,Tulek B,KANAT F Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?. . 2021; 224 - 230.
IEEE	Cizmecioglu A,YORMAZ B,Akay Çizmecioğlu H,Göktepe M,ahmadlı n,Ergün D,Tulek B,KANAT F "Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?." , ss.224 - 230, 2021.
ISNAD	Cizmecioglu, Ahmet vd. "Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?". (2021), 224-230.

APA	Cizmecioglu A, YORMAZ B, Akay Çizmecioğlu H, Göktepe M, ahmadlı n, Ergün D, Tulek B, KANAT F (2021). Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?. Selçuk Tıp Dergisi, 37(3), 224 - 230.
Chicago	Cizmecioglu Ahmet,YORMAZ BURCU,Akay Çizmecioğlu Hilal,Göktepe Mevlüt Hakan,ahmadlı nijat,Ergün Dilek,Tulek Baykal,KANAT FIKRET Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?. Selçuk Tıp Dergisi 37, no.3 (2021): 224 - 230.
MLA	Cizmecioglu Ahmet,YORMAZ BURCU,Akay Çizmecioğlu Hilal,Göktepe Mevlüt Hakan,ahmadlı nijat,Ergün Dilek,Tulek Baykal,KANAT FIKRET Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?. Selçuk Tıp Dergisi, vol.37, no.3, 2021, ss.224 - 230.
AMA	Cizmecioglu A,YORMAZ B,Akay Çizmecioğlu H,Göktepe M,ahmadlı n,Ergün D,Tulek B,KANAT F Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?. Selçuk Tıp Dergisi. 2021; 37(3): 224 - 230.
Vancouver	Cizmecioglu A,YORMAZ B,Akay Çizmecioğlu H,Göktepe M,ahmadlı n,Ergün D,Tulek B,KANAT F Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?. Selçuk Tıp Dergisi. 2021; 37(3): 224 - 230.
IEEE	Cizmecioglu A,YORMAZ B,Akay Çizmecioğlu H,Göktepe M,ahmadlı n,Ergün D,Tulek B,KANAT F "Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?." Selçuk Tıp Dergisi, 37, ss.224 - 230, 2021.
ISNAD	Cizmecioglu, Ahmet vd. "Is Capillary Refill Time an Early Prognostic Factor in COVID-19 Patients?". Selçuk Tıp Dergisi 37/3 (2021), 224-230.